Olvan Trio 40 Mg Tablet (10 Tab)

OLVAN TRIO 40 MG TABLET

Name

• Brand Name: Olvan Trio 40 Tablet
• Manufacturer: Sun Pharmaceutical Industries Ltd.

Composition Olvan Trio 40 Tablet is a combination medication containing three active ingredients:

• Olmesartan Medoxomil (40 mg)
• Cilnidipine (10 mg)
• Chlorthalidone (12.5 mg)

Uses This medication is primarily used to treat hypertension (high blood pressure). It is often prescribed when a single medication is not effective in controlling blood pressure. By lowering high blood pressure, it helps reduce the risk of future heart attacks, strokes, and kidney problems.

Dosage and Administration

• Olvan Trio 40 Tablet should be taken orally with food.
• The tablet should be swallowed whole; do not chew, crush, or break it.
• It is recommended to take the medicine at the same time each day for optimal results.
• The dosage and duration of treatment are determined by a doctor based on the patient's medical condition.
• As it contains a diuretic, it's advisable to avoid taking it within four hours of bedtime to prevent increased urination.
• Do not stop taking the medicine abruptly, as this may increase the risk of heart attack or stroke.

Side Effects Common side effects may include:

• Ankle swelling
• Headache
• Dizziness
• Tiredness/Fatigue
• Nausea
• Upset stomach/Abdominal pain
• Taste changes
• Increased urination frequency
• Palpitations
• Sleepiness

Serious side effects can include severe dizziness or fainting, muscle cramps or irregular heartbeat (due to low potassium), yellowing of eyes or skin (liver issues), sudden weight gain or swelling (kidney issues), or allergic reactions like skin rash or trouble breathing.

Precautions

• Pregnancy and Breastfeeding: Olvan Trio 40 Tablet is unsafe during pregnancy, especially in the second and third trimesters, and should be avoided. It is also probably unsafe to use during breastfeeding.
• Allergies: Do not take if allergic to any ingredients in Olvan Trio Tablet.
• Pre-existing Conditions: Caution is advised in patients with severe kidney disease, liver disease, low blood pressure, or heart conditions like cardiogenic shock or aortic stenosis. Regular monitoring of kidney function, electrolyte levels, and blood sugar is essential.
• Alcohol: Avoid alcohol consumption as it can enhance the blood pressure-lowering effect and increase the risk of dizziness and fainting.
• Drug Interactions: Inform your doctor about all other medications, especially other antihypertensives, NSAIDs (e.g., ibuprofen), and heart medications like digoxin. Avoid grapefruit juice and St. John's wort.
• Diet: Limit sodium chloride intake and avoid salt substitutes high in potassium.

Storage Store in a cool and dry place away from direct sunlight, heat, and moisture. Keep out of sight and reach of children. Ideally, store below 30°C or between 10ºC to 25ºC.

Here are some frequently asked questions about OLVAN TRIO 40 MG TABLET:

What is OLVAN TRIO 40 MG TABLET used for?

OLVAN TRIO 40 MG TABLET is primarily used to treat hypertension, commonly known as high blood pressure, especially when a single medication is not sufficient to control it. By effectively lowering high blood pressure, it helps to reduce the risk of future heart attacks, strokes, and kidney problems.

How does OLVAN TRIO 40 MG TABLET work?

OLVAN TRIO 40 MG TABLET is a combination medication containing three active ingredients: Olmesartan medoxomil, Cilnidipine, and Chlorthalidone.

• Olmesartan medoxomil is an angiotensin receptor blocker (ARB) that works by blocking the hormone angiotensin, which helps relax and widen blood vessels.
• Cilnidipine is a calcium channel blocker (CCB) that blocks calcium channels in blood vessels, further relaxing them and reducing the heart's workload.
• Chlorthalidone is a diuretic (water pill) that removes excess water and certain electrolytes from the body through urine, contributing to lower blood pressure and improving blood flow. Together, these components work to widen and relax blood vessels, reduce fluid retention, and decrease the heart's workload, thereby effectively lowering blood pressure.

What is the usual dosage for OLVAN TRIO 40 MG TABLET?

The dosage and duration of treatment for OLVAN TRIO 40 MG TABLET should be determined by your doctor based on your specific medical condition. It is generally recommended to take this medicine with food and at the same time each day for optimal results. Due to its diuretic component, it's often advised to avoid taking it within four hours of going to bed to prevent frequent urination during the night. Do not exceed the prescribed dose.

What are the possible side effects of OLVAN TRIO 40 MG TABLET?

Common side effects can include headache, dizziness, fatigue, ankle swelling (peripheral edema), nausea, stomach pain, muscle cramps, palpitations, sleepiness, taste changes, and increased urination frequency. More serious side effects, though less common, can include severe dizziness or fainting, irregular heartbeat (due to low potassium), yellowing of the eyes or skin (signs of liver problems), sudden weight gain or swelling (signs of kidney issues), skin rash, itching, or trouble breathing (possible allergic reaction). If any side effects persist, worsen, or are severe, you should consult your doctor.

Is OLVAN TRIO 40 MG TABLET safe during pregnancy or breastfeeding?

OLVAN TRIO 40 MG TABLET is generally considered unsafe and is not recommended during pregnancy, especially during the second and third trimesters, as it may cause harm to the unborn baby. If you become pregnant while taking this medicine, you should discontinue it and immediately consult your doctor. Similarly, it is not recommended for use during breastfeeding, as components of the medicine can pass into breast milk, and its effect on infants is not well known. Your doctor can advise on safer alternative treatments.

Can OLVAN TRIO 40 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all other medications, herbal preparations, and supplements you are currently taking or plan to take.

• Other Antihypertensives: OLVAN TRIO 40 MG TABLET may enhance the blood pressure-lowering effects of other antihypertensive medicines like amlodipine and lisinopril, potentially leading to lower-than-expected blood pressure.
• NSAIDs: Medicines such as ibuprofen and naproxen can decrease the blood pressure-lowering effect of OLVAN TRIO 40 MG TABLET.
• Aliskiren: Co-administration with aliskiren is not recommended, particularly in patients with diabetes or kidney disease, due to an increased risk of serious adverse effects.
• Lithium: Concomitant use with lithium is not recommended.
• Potassium Supplements/Potassium-sparing Diuretics: Use with caution, as it may increase potassium levels.
• Alcohol: Avoid consuming alcohol as it can enhance the blood pressure-lowering effect and increase the risk of dizziness and fainting.
• Grapefruit juice and St. John's wort should not be consumed with this medication.

What precautions should be taken while taking OLVAN TRIO 40 MG TABLET?

Inform your doctor if you have any pre-existing medical conditions, especially liver or kidney problems, heart failure, very low blood pressure, diabetes, gout, or electrolyte imbalances. Regular monitoring of your blood pressure, kidney function, electrolyte levels (potassium, sodium, magnesium), and blood sugar is essential to ensure the medication is working effectively and to detect any potential issues. This medicine may cause dizziness or tiredness, so be cautious when driving or operating machinery. Staying adequately hydrated by drinking plenty of fluids can help alleviate certain side effects like muscle weakness, dry mouth, and extreme thirst, but follow your doctor's guidance on fluid intake.

What happens if a dose of OLVAN TRIO 40 MG TABLET is missed?

If you miss a dose of OLVAN TRIO 40 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should OLVAN TRIO 40 MG TABLET be stored?

Store OLVAN TRIO 40 MG TABLET in a cool and dry place, away from direct sunlight, heat, and moisture. Keep it out of the sight and reach of children and pets. The recommended storage temperature is typically between 10ºC to 30ºC.