Oxra S 10/100 Mg Tablet (15 Tab)

OXRA S 10/100 MG Tablet

OXRA S 10/100 MG Tablet is a combination medication used in the management of type 2 diabetes mellitus. It is manufactured by SUN PHARMA LABORATORIES LTD..

• Composition: Each tablet contains Dapagliflozin 10 mg and Sitagliptin 100 mg.

  • Dapagliflozin is a sodium-glucose cotransporter-2 (SGLT2) inhibitor that works by increasing the excretion of glucose in the urine, thereby lowering blood glucose levels.
  • Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that increases insulin levels and decreases glucagon levels, which helps to reduce glucose production by the liver and control blood sugar.

• Uses: OXRA S 10/100 MG Tablet is primarily prescribed for:

  • The management of type 2 diabetes mellitus in adults whose blood sugar levels are not adequately controlled by metformin alone, or in conjunction with diet and exercise.
  • Reducing the risk of cardiovascular death, hospitalization for heart failure, and the risk of worsening kidney disease in adults with type 2 diabetes and established cardiovascular disease or multiple cardiovascular risk factors.

• Dosage and Administration: This medicine should be taken orally, with or without food, usually once daily in the morning. It is recommended to take it at the same time each day for consistent results. The dosage is determined by a healthcare professional based on the patient's medical condition and response to treatment. Do not stop taking the medication without consulting a doctor.

• Side Effects: Common side effects may include:

  • Urinary tract infections (UTIs)
  • Nasal congestion, sore throat, or upper respiratory tract infections (nasopharyngitis)
  • Headache
  • Genital fungal infections
  • Frequent urination (polyuria)
  • Dizziness
  • Gastrointestinal issues like flatulence, constipation, stomach pain, or diarrhea

  Serious side effects can include:

  • Pancreatitis (severe and persistent stomach pain)
  • Severe allergic reactions (rash, swelling of face/lips/tongue, difficulty breathing)
  • Dehydration, especially if accompanied by nausea, vomiting, or restricted food intake
  • Hypoglycemia (low blood sugar) when used with insulin or sulfonylureas.

• Precautions:

  • Inform your doctor if you have kidney or liver problems, heart failure, or a history of urinary tract infections.
  • Not recommended for patients with type 1 diabetes or diabetic ketoacidosis.
  • Caution is advised if you are taking other anti-diabetic medications, diuretics, or medicines for fungal or bacterial infections.
  • Avoid excessive alcohol intake as it may increase the risk of side effects.
  • Pregnant or breastfeeding women should consult their doctor before taking this medicine.
  • Regular monitoring of blood sugar levels is essential during treatment.

• Storage: Store OXRA S 10/100 MG Tablet in a cool and dry place, typically below 30°C or at room temperature, away from direct sunlight and moisture. Keep it out of the sight and reach of children and pets.

What is OXRA S 10/100 MG Tablet used for?

OXRA S 10/100 MG Tablet is primarily used to treat type 2 diabetes mellitus in adults, especially when blood sugar levels are not adequately controlled by other medications like metformin alone. This medicine also helps reduce the risk of serious diabetes-related complications such as kidney damage, nerve problems, eye damage, cardiovascular events, and hospitalization for heart failure.

How does OXRA S 10/100 MG Tablet work?

OXRA S 10/100 MG Tablet contains two active ingredients: Dapagliflozin (10 mg) and Sitagliptin (100 mg). Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, works by increasing the amount of glucose excreted from the body through urine, thereby lowering blood glucose levels. Sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, increases the levels of natural substances called incretins. Incretins help regulate blood sugar by stimulating insulin release, particularly after meals, and by decreasing the amount of sugar the liver produces.

What is the usual dosage for OXRA S 10/100 MG Tablet?

The usual dosage involves taking one tablet orally once daily, with or without food, preferably at the same time each day. Your doctor will determine the appropriate dose and duration of treatment based on your medical condition and response. It's important not to stop taking the medication without consulting your doctor.

What are the possible side effects of OXRA S 10/100 MG Tablet?

Common side effects may include genital yeast infections, urinary tract infections, increased urination, dehydration, low blood pressure, headache, nasopharyngitis (cold-like symptoms such as runny nose and sore throat), stomach upset, joint pain, nausea, vomiting, diarrhea, flatulence, and constipation. Serious but rare side effects can include pancreatitis or severe allergic reactions. Drink plenty of fluids to help prevent dehydration.

Is OXRA S 10/100 MG Tablet safe during pregnancy or breastfeeding?

Caution is advised when taking OXRA S 10/100 MG Tablet during pregnancy or breastfeeding. It should only be used in pregnant women if clearly necessary, and with caution in breastfeeding women due to limited available data. Always consult your doctor for advice if you are pregnant, planning a pregnancy, or breastfeeding.

Can OXRA S 10/100 MG Tablet be taken with other medications?

Yes, OXRA S 10/100 MG Tablet can be combined with other antidiabetic medications, including insulin, to achieve better blood glucose control. However, dosage adjustments or close monitoring may be necessary to minimize the risk of hypoglycemia (low blood sugar). It is crucial to inform your healthcare provider about all other medications, herbal products, or supplements you are currently taking or plan to take, as certain drugs like diuretics, antifungals (e.g., ketoconazole), antivirals (e.g., ritonavir), antibiotics (e.g., clarithromycin), immunosuppressants (e.g., ciclosporin), and cardiac glycosides (e.g., digoxin) may interact with it.

What precautions should be taken while using OXRA S 10/100 MG Tablet?

Before taking OXRA S 10/100 MG Tablet, inform your doctor if you have any pre-existing medical conditions such as kidney or liver problems, heart disease, urinary tract infections, inflammation of the pancreas (pancreatitis), gallstones, alcohol dependence, or very high levels of triglycerides. Stay well-hydrated by drinking plenty of fluids, and avoid excessive alcohol consumption. Regular monitoring of blood sugar levels is essential. Do not stop taking the medicine abruptly, as this can increase blood sugar levels and the risk of complications. If you experience dizziness or light-headedness, avoid driving or operating machinery.

What happens if a dose of OXRA S 10/100 MG Tablet is missed?

If you miss a dose of OXRA S 10/100 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should OXRA S 10/100 MG Tablet be stored?

OXRA S 10/100 MG Tablet should be stored in a cool and dry place, away from direct sunlight and moisture, at a temperature not exceeding 30°C. Keep it out of the sight and reach of children.