Acenac Mr 8 Tablet

ACENAC MR 8 TABLET by MEDLEY PHARMACEUTICALS LTD.

Name

• Brand Name: ACENAC MR 8 TABLET
• Manufacturer: Medley Pharmaceuticals Ltd.

Composition

ACENAC MR 8 TABLET is a combination medicine containing three active ingredients:

• Aceclofenac (100 mg): A non-steroidal anti-inflammatory drug (NSAID) that inhibits prostaglandins causing pain and inflammation.
• Paracetamol/Acetaminophen (325 mg): An analgesic and antipyretic.
• Thiocolchicoside (8 mg): A muscle relaxant that works on the central nervous system to relieve muscle stiffness and improve movement.

Uses

ACENAC MR 8 TABLET is primarily used to relieve pain and inflammation associated with musculoskeletal and joint disorders. It is prescribed for:

• Lower back pain
• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing spondylitis
• Acute musculoskeletal disorders, including muscle spasms due to injury
• Post-operative pain
• Neck and shoulder pain
• Sciatica
• Degenerative vertebral disorders

Dosage and Administration

The dosage should be as advised by a doctor and may vary based on the patient's condition. It is recommended to take ACENAC MR 8 TABLET with food to prevent stomach upset. It should be swallowed whole and not chewed or crushed. The usual adult dose mentioned in some sources is one tablet, possibly up to 3 times daily, or 8 mg to 16 mg per day, with treatment duration sometimes being around 7 days, but this is always subject to medical advice.

Side Effects

Common side effects include:

• Dyspepsia (indigestion)
• Diarrhoea
• Abdominal pain / Stomach pain
• Nausea and Vomiting
• Dizziness and Sleepiness/Drowsiness
• Rash and Pruritus (itching)
• Oedema (swelling)
• Heartburn
• Loss of appetite
• Dry mouth More serious side effects can include increased liver enzymes and gastrointestinal bleeding. If side effects persist or worsen, medical consultation is advised.

Precautions

• Pregnancy and Breastfeeding: Not recommended during pregnancy, and potentially unsafe during breastfeeding; consult a doctor.
• Alcohol: Avoid alcohol consumption as it may increase drowsiness, dizziness, and the risk of stomach bleeding or liver damage.
• Underlying Conditions: Use with caution in patients with kidney disease, liver disease, asthma, heart issues, high blood pressure, bleeding disorders, or chronic malnutrition.
• Interactions: Inform your doctor about all existing medications as it can interact with anticoagulants (e.g., warfarin), other NSAIDs, corticosteroids, and certain medicines for nausea, hypertension, depression, gout, heart conditions, and HIV.
• Driving/Operating Machinery: May cause drowsiness and dizziness; avoid such activities if affected.
• Children: Not recommended for use in children as safety and efficacy are not established.

Storage

Store in a cool and dry place, away from sunlight, typically between 10ºC to 25ºC or below 30ºC. Keep out of reach and sight of children.

ACENAC MR 8 TABLET by MEDLEY PHARMACEUTICALS LTD. is a combination medicine containing Aceclofenac (100mg), Paracetamol (Acetaminophen) (325mg), and Thiocolchicoside (8mg). It is primarily used to relieve pain, inflammation, and muscle spasms associated with various musculoskeletal conditions.

Here are some frequently asked questions about ACENAC MR 8 TABLET:

What is ACENAC MR 8 TABLET used for?

ACENAC MR 8 TABLET is used to treat mild to moderate pain, inflammation, and muscle spasms. This includes conditions such as lower back pain, neck pain, sprains, strains, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and post-operative pain.

How does ACENAC MR 8 TABLET work?

This medicine combines three active ingredients:

• Aceclofenac: A non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation by blocking the production of chemical messengers called prostaglandins.
• Paracetamol (Acetaminophen): An analgesic (pain reliever) and antipyretic (fever reducer) that acts through central and peripheral mechanisms to alleviate pain and control fever.
• Thiocolchicoside: A muscle relaxant that acts on the centers of the spinal cord and brain, and on GABA receptors, to relieve muscle stiffness and spasms and improve muscle movement. Together, these ingredients provide comprehensive relief from pain, inflammation, and muscle stiffness.

What is the usual dosage for ACENAC MR 8 TABLET?

The usual dosage is one tablet, taken once or twice daily, or as prescribed by your doctor. It should be taken with food to minimize the risk of stomach upset. Always follow your doctor's instructions regarding the dose and duration of treatment, as this can vary based on your condition and response to the medication.

What are the possible side effects of ACENAC MR 8 TABLET?

Common side effects include nausea, vomiting, stomach pain, diarrhea, dizziness, drowsiness, heartburn, and loss of appetite. Less common side effects can include itching, skin rash, and increased liver enzymes. Serious but rare side effects may involve gastrointestinal bleeding or ulcers, severe allergic reactions, liver or kidney problems, difficulty breathing, or chest pain. If any side effects persist or worsen, consult your doctor.

Is ACENAC MR 8 TABLET safe during pregnancy or breastfeeding?

ACENAC MR 8 TABLET is generally not recommended during pregnancy due to potential risks and harm to the fetus. It is also contraindicated in breastfeeding women as its components can pass into breast milk and may cause adverse effects in the infant. It is crucial to consult your doctor before using this medicine if you are pregnant, planning a pregnancy, or breastfeeding.

Can ACENAC MR 8 TABLET be taken with other medications?

ACENAC MR 8 TABLET can interact with several other medications. These include other NSAIDs (like ibuprofen or aspirin), blood thinners (anticoagulants such as warfarin), corticosteroids, methotrexate, lithium, diuretics, antihypertensive medications (for high blood pressure), certain antibiotics (e.g., ciprofloxacin, moxifloxacin), and antidepressants. Always inform your doctor about all medicines, supplements, and herbal products you are currently taking to avoid potential drug interactions.

What precautions should be taken while using ACENAC MR 8 TABLET?

Avoid taking this medicine if you have known allergies to its ingredients, a history of peptic ulcers, gastrointestinal bleeding, or severe liver/kidney disease. Use with caution if you have heart problems, high blood pressure, asthma, or epilepsy/seizure disorders. Alcohol consumption should be avoided as it can increase the risk of stomach problems and liver damage. This medicine may cause drowsiness or dizziness, so avoid driving or operating heavy machinery until you know how it affects you. It is not recommended for children under 16 years of age and should be used with caution in elderly patients.

What happens if a dose of ACENAC MR 8 TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should ACENAC MR 8 TABLET be stored?

Store ACENAC MR 8 TABLET in a cool, dry place, typically below 30°C, away from direct sunlight, heat, and moisture. Keep the medicine out of reach of children. Always check the expiry date and use the medicine before it expires.