New Folinal Plus Tablet

NEW FOLINAL PLUS TABLET by ALEMBIC PHARMACEUTICALS LTD

Name:

• Brand Name: NEW FOLINAL PLUS TABLET

Composition: NEW FOLINAL PLUS TABLET is a combination of L-Methylfolate, Methylcobalamin, and Pyridoxal Phosphate (which is the active form of Vitamin B6). Specifically, it contains L-Methylfolate Calcium USP (equivalent to L-Methylfolate), Mecobalamin JP, and Pyridoxal 5 Phosphate.

Uses: This vitamin supplement is used to treat nutritional deficiencies. It helps manage endothelial dysfunction or hyperhomocysteinemia, particularly in patients with lower extremity ulceration. It also promotes optimum health and protects nerve cells in diabetic peripheral neuropathy (nerve damage due to high blood sugar levels). Furthermore, it is beneficial for megaloblastic or folate-deficiency anemia, supports healthy red blood cell production, and nerve health. It may also be used during pregnancy and lactation to prevent neurological disorders and reduce the risk of preterm birth.

Dosage and Administration: Take NEW FOLINAL PLUS TABLET as advised by your physician. Swallow the tablet whole with a glass of water; do not crush or chew it. It can be taken with or without food, but it is best to take it at a fixed time each day for consistent levels in the body. Your doctor will determine the correct dose and duration based on age, body weight, and disease condition. Do not exceed the recommended dosage.

Side Effects: Common side effects include allergic reactions, acne, skin reactions, light sensitivity, nausea, vomiting, abdominal pain, loss of appetite, mild diarrhea, tingling or pricking sensation, sleepiness, and headaches. Rarely, more serious side effects like polycythemia vera (a type of blood cancer) have been noted. Consult your doctor if any side effects worsen or persist.

Precautions:

• Pregnancy and Breastfeeding: Use with caution and only if prescribed by a doctor.
• Allergy: Avoid if allergic to any components of the tablet.
• Medical Conditions: Inform your doctor if you have existing conditions such as diabetes, hypertension, kidney, or liver problems. It is not recommended for use if you have Leber's Disease, as it may worsen the condition.
• Drug Interactions: Inform your doctor about all other medicines, supplements, or herbal products you are taking to avoid undesired effects.
• Alcohol: Avoid consuming alcohol during treatment, as it may reduce the effectiveness of the medicine.
• Children: Not proven safe or effective in children; consult a doctor before use.
• Driving: Exercise caution if you experience disturbed mental alertness or motor coordination.

Storage: Keep NEW FOLINAL PLUS TABLET out of reach of children. Store in a cool and dry place, protected from light and moisture, at a temperature not exceeding 25°C or below 30°C.

What is NEW FOLINAL PLUS TABLET used for?

NEW FOLINAL PLUS TABLET is primarily used to manage endothelial dysfunction (where blood vessels don't widen properly) or hyperhomocysteinemia (high levels of an amino acid called homocysteine), especially in patients with lower extremity ulceration. It also helps promote overall health and protects nerve cells in diabetic peripheral neuropathy, a condition involving nerve damage due to diabetes. Additionally, it is used to treat nutritional deficiencies, including certain types of anemia (low red blood cell count), and is beneficial during pregnancy and lactation to prevent neurological disorders and reduce the risk of preterm birth.

How does NEW FOLINAL PLUS TABLET work?

NEW FOLINAL PLUS TABLET is a vitamin supplement containing a combination of L-Methylfolate (Vitamin B9), Methylcobalamin (Vitamin B12), and Pyridoxal Phosphate (Vitamin B6).

• L-Methylfolate is an active form of folate essential for DNA synthesis, cell division, and the formation of red blood cells. It helps increase blood flow to peripheral nerves and supports hemoglobin formation, which carries oxygen throughout the body.
• Methylcobalamin plays a crucial role in nerve function, red blood cell production, and DNA synthesis. It helps maintain nerve cells and their protective sheaths and supports brain health.
• Pyridoxal Phosphate is the active form of Vitamin B6, involved in protein, fat, and carbohydrate metabolism, as well as the creation of red blood cells and neurotransmitters. It can also help reduce feelings of nausea.

What is the usual dosage for NEW FOLINAL PLUS TABLET?

NEW FOLINAL PLUS TABLET should be taken as advised by your physician. Swallow the tablet whole with a glass of water; do not crush or chew it. Your doctor will determine the correct dose and duration based on your age, body weight, disease condition, and the severity of your deficiency. For optimal effectiveness, it is often recommended to take the tablet at the same time each day to maintain consistent levels of the vitamins in your body. Do not exceed the prescribed dosage.

What are the possible side effects of NEW FOLINAL PLUS TABLET?

Common side effects may include allergic reactions, acne, skin reactions, sensitivity to light, nausea, vomiting, abdominal pain, loss of appetite, mild diarrhea, a tingling or pricking sensation, sleepiness, headaches, itching, temporary skin rash, and swelling of the entire body. These side effects usually do not require medical attention and tend to resolve over time. However, if any symptoms persist or worsen, you should consult your doctor. Rarely, severe allergic reactions may occur. High doses of folic acid, an ingredient in the tablet, might also mask a Vitamin B12 deficiency.

Is NEW FOLINAL PLUS TABLET safe during pregnancy or breastfeeding?

During pregnancy, NEW FOLINAL PLUS TABLET should be used with caution and only if advised by your doctor, as it is considered essential for the overall development of the fetus and the well-being of the pregnant woman. If you are pregnant, think you may be pregnant, or are planning to get pregnant, consult your doctor before taking this medicine. For breastfeeding women, it should also be used with caution and after consulting a doctor. While some sources indicate it does not pass into breast milk in a significant amount and is not harmful to the baby, it's best to seek medical advice.

Can NEW FOLINAL PLUS TABLET be taken with other medications?

Before taking NEW FOLINAL PLUS TABLET, inform your doctor about all other prescription, non-prescription, or herbal medicines and supplements you are currently taking, as they might interact and cause serious side effects. Specific medications known to interact include pyrimethamine, pentamidine (used for parasitic infections), certain medicines for fits (e.g., carbamazepine, phenytoin, valproic acid), levodopa (for Parkinson's disease), some antibiotics (e.g., erythromycin, cefixime), and medicines used to control blood cholesterol levels (e.g., cholestyramine, colestipol).

What precautions should be taken while using NEW FOLINAL PLUS TABLET?

It is important to inform your doctor if you have any existing medical conditions, such as diabetes, hypertension, kidney or liver problems, or malabsorption syndrome (difficulty absorbing nutrients from food). Avoid taking this medicine if you are allergic to any of its components. It is also advisable to avoid or reduce alcohol intake during treatment, as it may decrease the effectiveness of the medicine. If you experience disturbed mental alertness or motor coordination, avoid driving or operating machinery. NEW FOLINAL PLUS TABLET is not recommended for use if you have Leber's Disease, as it may worsen your condition. Consult your doctor before giving this medicine to children.

What happens if a dose of NEW FOLINAL PLUS TABLET is missed?

If you forget to take a dose of NEW FOLINAL PLUS TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten one.

How should NEW FOLINAL PLUS TABLET be stored?

NEW FOLINAL PLUS TABLET should be stored in a cool and dry place, away from direct sunlight and moisture. Keep it out of the reach and sight of children to prevent accidental ingestion. It is typically recommended to store it at a temperature not exceeding 25°C or below 30°C.