Pregeb M Od 150 Mg Tablet (10 Tab)

PREGEB M OD 150 MG TABLET

PREGEB M OD 150 MG TABLET is a prescription medicine manufactured by Torrent Pharmaceuticals Ltd., primarily used for the management of neuropathic pain. The "OD" in its name signifies a once-daily, sustained-release formulation.

• Name:
  • Brand Name: PREGEB M OD 150 MG TABLET, Pregeb M OD 150 Tablet
• Composition:
  • Active Ingredients: Each tablet contains Pregabalin (150 mg) and Methylcobalamin (1500 mcg).
• Uses:
  • It is primarily prescribed for the treatment of neuropathic pain, which is pain caused by nerve damage due to various conditions such as diabetes, shingles, postherpetic neuralgia, fibromyalgia, and spinal cord injury.
  • Pregabalin, an anticonvulsant, works by modulating calcium channel activity in nerve cells, thereby reducing pain signals.
  • Methylcobalamin, a form of Vitamin B12, supports nerve health by aiding in the production of myelin, a protective sheath around nerve fibers, and helps regenerate damaged nerve cells.
• Dosage and Administration:
  • PREGEB M OD 150 MG TABLET is typically taken orally, with or without food, preferably at bedtime, as directed by a healthcare provider.
  • It is important to take the medicine at the same time each day to maintain consistent levels in the body.
  • The dosage and duration depend on the individual's condition and response to treatment.
  • Do not stop taking this medication suddenly without consulting a doctor, as it can lead to withdrawal symptoms.
• Side Effects:
  • Common Side Effects: Dizziness, sleepiness, headache, dry mouth, blurred vision, weight gain, difficulty concentrating, peripheral edema (swelling in extremities), increased appetite, tremor, nausea, constipation, and fatigue.
  • Serious Side Effects: Mood changes (e.g., depression, anxiety, irritability), memory problems, speech difficulties, coordination problems, muscle twitching or cramps, sexual dysfunction, vision changes (e.g., double vision), allergic reactions (swelling of face, lips, tongue, or throat; difficulty breathing), and suicidal thoughts.
• Precautions:
  • Avoid alcohol consumption during treatment, as it can increase drowsiness and other side effects.
  • This medicine may cause dizziness or sleepiness; therefore, avoid driving or operating heavy machinery until you know how it affects you.
  • Use with caution in pregnant or breastfeeding women; consult a doctor.
  • Patients with kidney disease, heart problems, or a history of substance abuse should use this medication with caution and under medical supervision.
  • Inform your doctor about all other medications, supplements, and herbal remedies you are taking to avoid potential drug interactions.
  • Report any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts to your doctor immediately.
• Storage:
  • Store in a cool and dry place, away from direct sunlight.
  • Keep out of sight and reach of children.
  • Store below 25°C or below 30°C.

What is PREGEB M OD 150 MG TABLET used for?

PREGEB M OD 150 MG TABLET is a combination medicine primarily used to manage neuropathic pain and fibromyalgia. Neuropathic pain is a chronic condition resulting from nerve damage or disease, often associated with diabetes, shingles, or spinal cord injury. It helps alleviate burning, shooting, aching sensations, tingling, and numbness associated with nerve pain. It may also be used in the treatment of partial seizures.

How does PREGEB M OD 150 MG TABLET work?

PREGEB M OD 150 MG TABLET contains two active ingredients: Pregabalin and Methylcobalamin. Pregabalin, an anticonvulsant, works by binding to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system, which reduces the release of neurotransmitters that transmit pain signals, thereby alleviating neuropathic pain. Methylcobalamin, a form of vitamin B12, is crucial for nerve health and regeneration. It aids in the formation of myelin, a protective sheath around nerve fibers, improving nerve conduction and helping to heal damaged nerve cells.

What is the usual dosage for PREGEB M OD 150 MG TABLET?

The recommended dosage of PREGEB M OD 150 MG TABLET varies based on the individual's condition and response to treatment. For neuropathic pain, the usual starting dose of pregabalin might be 75 mg per day, which can be adjusted up to a maximum of 600 mg per day, divided into two or three doses. For fibromyalgia, the recommended dose ranges from 300 to 450 mg per day. The "OD" in the name signifies "Once Daily", indicating a sustained-release formulation designed for convenient, once-a-day administration, often taken orally with or without food, preferably at bedtime. It is important to take it at the same time each day to maintain consistent medicine levels. Your doctor will determine the correct dose and duration of treatment.

What are the possible side effects of PREGEB M OD 150 MG TABLET?

Common side effects of PREGEB M OD 150 MG TABLET include dizziness, sleepiness/drowsiness, headache, dry mouth, blurred vision, weight gain, increased appetite, and peripheral edema (swelling in the extremities). Other possible side effects include nausea, vomiting, constipation, diarrhea, fatigue, and difficulty concentrating. If side effects persist or worsen, it is important to consult your doctor.

Is PREGEB M OD 150 MG TABLET safe during pregnancy or breastfeeding?

PREGEB M OD 150 MG TABLET is generally not recommended for use during pregnancy or breastfeeding, as safety and efficacy have not been fully evaluated. It is considered a category C medicine for pregnancy. If you are pregnant, planning a pregnancy, or breastfeeding, you should consult your doctor to assess the potential benefits versus risks. If you are a woman of childbearing age, effective contraception methods are advised during treatment.

Can PREGEB M OD 150 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all other medications, supplements, and herbal remedies you are currently taking before starting PREGEB M OD 150 MG TABLET to avoid potential drug interactions. Pregabalin may potentiate the effects of ethanol (alcohol) and certain central nervous system depressants like lorazepam, opioids, and benzodiazepines, potentially increasing the risk of drowsiness and other side effects. Methylcobalamin may interact with certain antibiotics like chloramphenicol and some medications for stomach acid reduction.

What precautions should be taken while taking PREGEB M OD 150 MG TABLET?

Avoid activities requiring alertness, such as driving or operating machinery, until you know how this medication affects you, as it can cause dizziness and drowsiness. Alcohol consumption should be avoided as it can increase drowsiness and other side effects. Inform your doctor if you have kidney problems, liver issues, heart conditions, or a history of substance abuse. Do not stop taking the medication abruptly without consulting your doctor, as it can lead to withdrawal symptoms or a worsening of your condition. PREGEB M OD 150 MG TABLET is not recommended for individuals below 18 years of age.

What happens if a dose is missed?

If you miss a dose of PREGEB M OD 150 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one, as this may increase the risk of unwanted side effects.

How should PREGEB M OD 150 MG TABLET be stored?

PREGEB M OD 150 MG TABLET should be stored in a cool, dry place away from direct sunlight and moisture, at room temperature (below 25°C or 30°C). Keep it out of reach of children and pets.