Amifru Plus Tablet (10 Tab)

AMIFRU PLUS TABLET

AMIFRU PLUS TABLET is a combination medicine manufactured by Torrent Pharmaceuticals Ltd.. It is primarily used to manage fluid retention (edema) and high blood pressure (hypertension).

• Composition: Each tablet contains Torasemide (10 mg) and Amiloride (5 mg). Torasemide is a loop diuretic, and Amiloride is a potassium-sparing diuretic. This combination helps remove excess fluid from the body while minimizing the loss of potassium.

• Uses: AMIFRU PLUS TABLET is prescribed for:

  • High blood pressure (hypertension).
  • Fluid retention (edema) associated with congestive heart failure.
  • Fluid accumulation linked with liver cirrhosis.
  • Edema resulting from chronic kidney disease.
  • Resistant edema caused by pulmonary hypertension.

• Dosage and Administration:

  • The medicine should be taken orally, swallowed whole with a glass of water, and not crushed or chewed.
  • It can be taken with or without food.
  • It is generally advised to take it preferably during the day, ideally in the morning, to avoid frequent nighttime urination. If taken twice a day, the second dose should be taken no later than early afternoon.
  • The dosage and duration will be determined by a healthcare professional based on the patient's condition and response. Do not exceed the prescribed dosage or stop the medication without consulting a doctor.

• Side Effects: Common side effects may include:

  • Dizziness, fatigue, and headache.
  • Nausea, vomiting, abdominal pain, diarrhea, or constipation.
  • Dry mouth.
  • Muscle cramps.
  • Electrolyte imbalances (e.g., hyponatremia, hypokalemia, or other low levels of sodium, potassium, magnesium, or calcium), and dehydration.
  • Less common but serious side effects can include severe allergic reactions, liver or kidney problems, muscle weakness, numbness/tingling, and easy bruising/bleeding.

• Precautions:

  • Inform your doctor about any pre-existing medical conditions, especially kidney disease, liver disease, heart problems, diabetes, gout, or electrolyte imbalances.
  • Caution is advised for pregnant and breastfeeding women; use only if potential benefits outweigh risks.
  • Avoid taking additional potassium supplements or potassium-rich foods (e.g., bananas, broccoli) as it may lead to hyperkalemia (excessive potassium in the blood).
  • Amifru Plus Tablet may cause drowsiness or dizziness; therefore, caution is advised when driving or operating machinery.
  • Limit alcohol intake as it may increase drowsiness.
  • Not recommended for children below 12 years of age.
  • Regular monitoring of electrolyte levels and kidney function is recommended during treatment.

• Storage: Keep AMIFRU PLUS TABLET out of the sight and reach of children.

What is Amifru Plus Tablet used for?

Amifru Plus Tablet is a combination medication primarily used to manage edema (fluid retention) and hypertension (high blood pressure). It helps to remove excess fluid from the body associated with conditions such as heart failure, liver cirrhosis, and kidney disease.

How does Amifru Plus Tablet work?

Amifru Plus Tablet contains two diuretic medicines: Torasemide (also referred to as Furosemide in some contexts) and Amiloride. Torasemide is a loop diuretic that works by inhibiting the reabsorption of sodium and chloride in the kidneys, leading to increased urine production and removal of excess water and electrolytes. Amiloride is a potassium-sparing diuretic that helps to prevent the excessive loss of potassium, which can occur with other diuretics, while still promoting the excretion of salt and water.

What is the usual dosage for Amifru Plus Tablet?

The dosage of Amifru Plus Tablet is determined by your doctor based on your specific medical condition and response to treatment. It is typically taken orally, usually once or twice a day. It is often recommended to take it in the morning to avoid frequent urination at night. You should take the tablet whole with water and avoid crushing or chewing it.

What are the possible side effects of Amifru Plus Tablet?

Common side effects can include dehydration, electrolyte imbalances (such as low sodium, potassium, magnesium, or calcium levels), headache, dizziness, nausea, vomiting, diarrhea or constipation, fatigue, and muscle cramps. More serious but less common side effects can include severe allergic reactions, liver or kidney problems, and muscle weakness. If you experience persistent or severe side effects, contact your doctor.

Is Amifru Plus Tablet safe during pregnancy or breastfeeding?

Caution is advised while taking Amifru Plus Tablet during pregnancy, and it should only be used if the potential benefits outweigh the risks. Some sources suggest it is generally considered safe if prescribed by a doctor during pregnancy and breastfeeding, with limited human data indicating no significant risk to the baby. However, other sources state it is contraindicated during pregnancy due to potential harm to the fetus and should be used with caution during breastfeeding. Always consult your doctor for personalized advice.

Can Amifru Plus Tablet be taken with other medications?

Amifru Plus Tablet can interact with various medications. It may interact with other diuretics, ACE inhibitors, angiotensin receptor blockers (which can increase the risk of high potassium levels), NSAIDs (which may reduce its effectiveness), cardiac glycosides, lithium, and certain antibiotics. It is crucial to inform your doctor about all other medications, supplements, and herbal products you are taking to avoid potential interactions.

What precautions should be taken while taking Amifru Plus Tablet?

Precautions include monitoring electrolyte levels and kidney function regularly, especially during long-term treatment. Patients with kidney disease, liver disease, diabetes, or gout should use this medicine with caution. Alcohol consumption should be limited or avoided as it can increase the risk of dizziness or drowsiness. Avoid potassium-rich foods or potassium supplements unless advised by your doctor, as Amiloride helps retain potassium. This medicine may cause dizziness or drowsiness, so exercise caution when driving or operating machinery.

What happens if a dose of Amifru Plus Tablet is missed?

If you miss a dose of Amifru Plus Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How should Amifru Plus Tablet be stored?

Amifru Plus Tablet should be stored below 30°C and protected from moisture and light.