Forglyn Inhaler

FORGLYN INHALER by ZYDUS HEALTHCARE LIMITED

Name

Brand Name: FORGLYN INHALER, FORGLYN CFC Free Inhaler Manufacturer: Zydus Healthcare Limited

Composition

FORGLYN INHALER typically contains a combination of two active ingredients:

• Formoterol Fumarate (4.8 mcg): A long-acting beta2-adrenergic agonist (LABA) that relaxes and widens the muscles around the airways, making breathing easier.
• Glycopyrrolate / Glycopyrronium (9 mcg): A long-acting anticholinergic (LAMA) that reduces airway constriction and decreases secretions in the airways.

Note: There is also a variant, FORGLYN PLUS INHALER, which includes an additional ingredient:

• Budesonide (160 mcg): An inhaled corticosteroid that reduces inflammation in the airways.

Uses

FORGLYN INHALER is primarily used for the long-term maintenance treatment of Chronic Obstructive Pulmonary Disease (COPD) in adults. This includes conditions such as chronic bronchitis and emphysema, by helping to improve airflow, reduce breathlessness, and control symptoms like wheezing and chest tightness. It is not intended for the relief of sudden breathing problems or acute asthma attacks.

Dosage and Administration

FORGLYN INHALER is administered via oral inhalation. The typical recommended dosage for FORGLYN INHALER 120 mdi is two inhalations twice daily, at the same time each day, or as directed by a healthcare professional.

Administration Guidelines:

• Prime the inhaler before first use or if it has not been used for more than a week.
• Shake the inhaler well before each use.
• Inhale deeply and slowly through the mouthpiece while pressing down on the inhaler to release the medicine.
• Hold your breath for a few seconds (around 2-3 seconds or up to 10 seconds), then exhale slowly.
• After use, rinse your mouth thoroughly with water and spit it out to reduce the risk of oral fungal infections like candidiasis.
• Do not use for sudden breathing problems; a short-acting bronchodilator should be available for such instances.

Side Effects

Common side effects may include:

• Nasopharyngitis (common cold symptoms)
• Oral candidiasis (yeast infection in the mouth)
• Upper respiratory tract infection
• Headache
• Back pain
• Cough
• Dry mouth
• Nausea
• Dizziness

Serious side effects, though less common, can include:

• Pneumonia
• Cardiovascular effects (e.g., high blood pressure, irregular heartbeat)
• Paradoxical bronchospasm (sudden worsening of breathing immediately after use)
• Narrow-angle glaucoma (with Forglyn Plus Inhaler)
• Allergic reactions

Precautions

• Allergy: Do not use if allergic to Formoterol, Glycopyrrolate, Budesonide (if using Forglyn Plus), or any other components of the medicine.
• Acute Symptoms: Not for acute bronchospasm or sudden breathing problems.
• Pre-existing Conditions: Caution is advised for patients with cardiovascular disorders (coronary insufficiency, cardiac arrhythmias, hypertension), convulsive disorders, thyrotoxicosis, narrow-angle glaucoma, urinary retention, prostatic hyperplasia, liver or kidney problems, or diabetes.
• Pregnancy and Breastfeeding: Consult a doctor. Caution is advised, and the benefits should outweigh the risks.
• Alcohol: Interaction with alcohol is unknown or generally advised against, as it may increase dizziness.
• Children: Not recommended for children below 18 years, as safety and effectiveness have not been established.

Storage

Store FORGLYN INHALER at room temperature, not exceeding 30°C. Protect it from direct sunlight and moisture. Keep it out of reach and sight of children.

What is Forglyn Inhaler used for?

Forglyn Inhaler is primarily used for the long-term maintenance treatment of Chronic Obstructive Pulmonary Disease (COPD) in adults. COPD is a group of lung diseases that includes chronic bronchitis and emphysema, causing symptoms like wheezing, shortness of breath, and chest tightness. It helps manage these symptoms and improve airflow. This inhaler is not intended for the relief of sudden breathing problems or acute COPD attacks; a short-acting rescue inhaler should be used for such situations.

How does Forglyn Inhaler work?

Forglyn Inhaler is a combination medication containing two active ingredients: Formoterol Fumarate and Glycopyrrolate. Formoterol Fumarate is a long-acting beta2-adrenergic agonist (LABA) that works by relaxing and widening the muscles around the airways in your lungs, making it easier to breathe. Glycopyrrolate is a long-acting anticholinergic (LAMA) that blocks certain receptors in your lungs, preventing airway constriction and reducing excess mucus production or secretions. Together, these two components work to provide comprehensive bronchodilation and improve lung function.

What is the usual dosage for Forglyn Inhaler?

The typical recommended dosage for Forglyn Inhaler is two inhalations twice daily, ideally at the same time each day. Your doctor will determine the precise dose and duration of treatment based on your specific medical condition and how you respond to the medication. It is crucial to follow your prescribed dosage and not exceed it without consulting your doctor.

What are the possible side effects of Forglyn Inhaler?

Common side effects may include nasopharyngitis (cold-like symptoms), oral candidiasis (a yeast infection in the mouth), upper respiratory tract infection, headache, back pain, and pneumonia. Other possible side effects can include nausea, dry mouth, chest pain, muscle cramps, dizziness, painful or frequent urination, and cough. Rinsing your mouth with water and spitting it out after each use can help reduce the risk of oral candidiasis. If you experience persistent or severe side effects, you should inform your doctor.

Is Forglyn Inhaler safe during pregnancy or breastfeeding?

Pregnancy: It is advisable to be cautious when using Forglyn Inhaler during pregnancy. Limited studies suggest it may be unsafe, with animal studies showing potential harmful effects on a developing baby. Always consult your doctor before starting this medicine if you are pregnant or planning to become pregnant.

Breastfeeding: Caution is advised while breastfeeding. Forglyn Inhaler is likely unsafe to use as human data suggests the drug may pass into breast milk and could potentially harm the baby. Long-term use might also reduce milk production. It is important to discuss this with your doctor to weigh the potential risks and benefits.

Can Forglyn Inhaler be taken with other medications?

Forglyn Inhaler can interact with certain medications. It is important to inform your doctor about all the medicines you are taking, including over-the-counter drugs, herbal products, and other inhalers. Specifically, interactions may occur with sympathomimetic agents (like ephedrine), other adrenergic medications (like salbutamol), and anticholinergic medicines (like atropine), which could intensify side effects or effects of the inhaler. Using other long-acting beta2-adrenergic agonists (LABA) with Forglyn Inhaler should be avoided. There are no known specific food interactions with Forglyn Inhaler.

What precautions should be taken when using Forglyn Inhaler?

• Do not use Forglyn Inhaler for sudden or acute breathing problems; use a fast-acting rescue inhaler for immediate relief.
• Rinse your mouth with water and spit it out after each inhalation to reduce the risk of oral fungal infections (candidiasis).
• Inform your doctor if you have cardiovascular disorders (e.g., heart problems, high blood pressure), convulsive disorders, thyrotoxicosis, narrow-angle glaucoma, urinary retention, or an enlarged prostate (prostatic hyperplasia).
• Exercise caution if you have liver or kidney health issues.
• Forglyn Inhaler may cause dizziness, so drive or operate machinery with caution until you know how it affects you.
• Avoid alcohol consumption as it may increase dizziness.
• The safety and effectiveness of Forglyn Inhaler have not been established in children below 18 years of age.
• Elderly patients may be more sensitive to side effects and require medical supervision.

What happens if a dose of Forglyn Inhaler is missed?

If you miss a dose of Forglyn Inhaler, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should Forglyn Inhaler be stored?

Forglyn Inhaler should be stored at room temperature, not exceeding 30°C. Keep it protected from direct sunlight and moisture. As it is a pressurized canister, it should be kept away from heat and not punctured or burned, even when empty. Always keep the inhaler out of the sight and reach of children.