Dynaduo 25mg Tab

DYNADUO 25MG TAB by MANKIND PHARMA LTD.

Name

• Brand Name: Dynaduo 25 Tablet
• Common Name: Empagliflozin + Linagliptin

Composition

Each tablet contains:

• Empagliflozin: 25 mg
• Linagliptin: 5 mg

Uses

Dynaduo 25 Tablet is primarily used in adults for the management of:

• Type 2 Diabetes Mellitus: To improve blood sugar control, typically when diet and exercise alone are insufficient. It helps regulate blood sugar by increasing glucose excretion through urine and enhancing insulin release.
• Cardiovascular Disease: To reduce the risk of cardiovascular death in adults with type 2 diabetes and established cardiovascular disease.
• Chronic Kidney Disease: To treat chronic kidney disease in adults with reduced kidney function, helping to protect kidneys from losing function.

Dosage and Administration

• Dynaduo 25 Tablet is taken orally, typically once daily.
• It can be taken with or without food, but it is recommended to take it at the same time each day for consistent blood levels.
• Swallow the tablet whole; do not chew, crush, or break it.
• The dosage is determined by a doctor based on the patient's medical condition and response to treatment.
• Do not stop taking the medication abruptly without consulting a doctor, as this can lead to increased blood sugar levels and potential complications.

Side Effects

Common side effects may include:

• Urinary tract infections (UTIs), including bladder pain, bloody or cloudy urine, or changes in vaginal color/amount/odor.
• Nasopharyngitis (inflammation of the throat and nasal passages) and upper respiratory tract infections.
• Frequent urination.
• Dizziness or lightheadedness.
• Cough, rash, itching.
• Low blood sugar (hypoglycemia), especially when used with other diabetes medications like insulin or sulfonylureas.
• Constipation, nausea, vomiting.

Precautions

• Type 1 Diabetes: Not recommended for patients with Type 1 diabetes or diabetic ketoacidosis.
• Kidney/Liver Issues: Use with caution in patients with kidney problems; not recommended in severe kidney disease. Regular monitoring of kidney function is important. Generally safe for liver disease if prescribed.
• Pregnancy & Breastfeeding: Generally not advised during pregnancy (especially second and third trimesters) or while breastfeeding. Consult a doctor if pregnant, planning a pregnancy, or breastfeeding.
• Alcohol: Avoid excessive alcohol consumption as it can affect blood sugar levels and increase the risk of dehydration or hypoglycemia.
• Hydration: Drink plenty of fluids to help prevent dehydration.
• Hygiene: Maintain good genital hygiene to prevent fungal infections.
• Drug Interactions: Inform your doctor about all medications, supplements, or herbal products being taken to avoid potential interactions, particularly with insulin or sulfonylureas, which can increase the risk of hypoglycemia.
• Other Conditions: Inform your doctor if you have a history of pancreatitis, heart disease, or joint pain, as this medication may worsen certain conditions.

Storage

• Store at room temperature (20°C to 25°C or below 30°C).
• Keep away from sunlight and moisture.
• Keep out of the sight and reach of children and pets.

DYNADUO 25MG Tablet, manufactured by Mankind Pharma Ltd., is a combination medication primarily used for the management of Type 2 Diabetes Mellitus. It contains Empagliflozin (25mg) and Linagliptin (5mg) as active ingredients.

Here are some frequently asked questions about DYNADUO 25MG Tablet:

What is DYNADUO 25MG Tablet used for?

DYNADUO 25MG Tablet is used in adults with Type 2 Diabetes Mellitus to help control blood sugar levels, especially when diet and exercise alone are not sufficient. It can also be prescribed to reduce the risk of cardiovascular death in adults with Type 2 Diabetes and established cardiovascular disease, and to treat chronic kidney disease in adults with reduced kidney function.

How does DYNADUO 25MG Tablet work?

DYNADUO 25MG Tablet combines two active ingredients: Empagliflozin and Linagliptin. Empagliflozin works by blocking a protein in the kidneys called sodium-glucose co-transporter 2 (SGLT-2), which leads to increased removal of glucose (sugar) from the body through urine. Linagliptin works by inhibiting an enzyme called dipeptidyl-peptidase 4 (DPP-4). This action increases the levels of natural substances (incretins) that help the pancreas produce more insulin when blood sugar levels are high and reduce the amount of glucose produced by the liver.

What is the usual dosage for DYNADUO 25MG Tablet?

The dosage of DYNADUO 25MG Tablet is determined by your doctor based on your individual condition and response to treatment. It should be taken exactly as prescribed, typically once daily, with or without food, preferably at the same time each day. Do not stop taking it or adjust the dose without consulting your doctor.

What are the possible side effects of DYNADUO 25MG Tablet?

Common side effects can include urinary tract infections (UTIs), nasopharyngitis (common cold-like symptoms), upper respiratory tract infections, frequent urination, genital fungal infections, cough, rash, itching, constipation, nausea, dizziness, and abdominal pain. Low blood sugar (hypoglycemia) is possible, especially if taken with other diabetes medications. Staying hydrated is important to help prevent dehydration.

Is DYNADUO 25MG Tablet safe during pregnancy or breastfeeding?

DYNADUO 25MG Tablet is generally not advised during pregnancy or breastfeeding, as there is limited information on its effects. It is specifically not safe to consume during the second and third trimesters of pregnancy. If you are pregnant, planning a pregnancy, or breastfeeding, you should discuss alternative diabetes treatments with your doctor.

Can DYNADUO 25MG Tablet be taken with other medications?

Yes, DYNADUO 25MG Tablet can be used with other diabetes medications if prescribed by your doctor. However, it is crucial to monitor your blood sugar levels closely, as combining medications can increase the risk of hypoglycemia or other adverse effects. Inform your doctor about all medicines, supplements, or herbal products you are currently taking, as some medications like diuretics or rifampin can interact with DYNADUO 25MG Tablet.

What precautions should be taken while using DYNADUO 25MG Tablet?

DYNADUO 25MG Tablet should not be taken if you have Type 1 diabetes, diabetic ketoacidosis, or severe kidney or liver disease. Use with caution if you have kidney or heart problems, or a history of pancreatitis. It is important to stay well-hydrated, and limit or avoid alcohol consumption, as it can cause fluctuations in blood sugar levels. Inform your doctor if you have any pre-existing medical conditions or are undergoing stress (like fever, infection, or surgery).

What happens if a dose of DYNADUO 25MG Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. Never miss your blood sugar medicines as it may lead to high blood sugar.

How should DYNADUO 25MG Tablet be stored?

Store DYNADUO 25MG Tablet at room temperature, away from moisture, excessive heat, and direct light. Keep it out of reach of children and pets. Do not use the medication past its expiration date.