Amtas M 25 Mg Tablet (15 Tab)

AMTAS M 25 MG TABLET

AMTAS M 25 MG TABLET, manufactured by INTAS PHARMACEUTICALS LTD., is a combination medication used to manage various cardiovascular conditions.

Composition

Each tablet contains two active ingredients:

• Amlodipine (5mg): A calcium channel blocker that relaxes and widens blood vessels, improving blood flow and reducing blood pressure.
• Metoprolol Succinate (25mg): A beta-blocker that slows the heart rate and reduces the force of heart contractions, thereby lowering blood pressure and reducing the heart's workload.

Uses

AMTAS M 25 MG TABLET is prescribed for the management of:

• High blood pressure (hypertension)
• Chest pain due to heart-related issues (angina pectoris)
• Coronary heart disease
• Abnormal heart rhythms
• Chronic heart failure

Dosage and Administration

This medicine should be taken orally as directed by your doctor, typically once daily. It can be consumed with or without food, but it is advisable to take it at the same time each day for consistent effectiveness. Do not alter the prescribed dose or discontinue the medication abruptly without consulting your doctor, as this can lead to serious complications.

Side Effects

Common side effects may include:

• Dizziness, fatigue, sleepiness
• Headache
• Nausea, abdominal pain, constipation
• Ankle swelling, peripheral edema
• Slow heart rate (bradycardia)
• Flushing, palpitations, visual disturbances

Serious side effects can occur if the medicine is stopped suddenly, potentially leading to severe chest pain, abnormal heart rhythms, or a heart attack.

Precautions

• Allergies: Do not take if you are allergic to Amlodipine, Metoprolol, or any other ingredients.
• Medical Conditions: Use with caution in patients with liver or kidney problems, diabetes, peripheral vascular disease, thyrotoxicosis, or bronchospastic diseases like asthma or COPD. It is contraindicated in certain heart conditions such as heart failure, irregular heartbeats, heart blockage, and metabolic acidosis.
• Pregnancy and Breastfeeding: Consult your doctor before using if you are pregnant or breastfeeding.
• Alcohol: Avoid consuming alcohol as it may increase the risk of side effects like low blood pressure and dizziness.
• Driving: This medicine may cause dizziness or fatigue, so avoid driving or operating heavy machinery until you know how it affects you.
• Drug Interactions: Inform your doctor about all current medications, including over-the-counter drugs, herbal supplements, and other blood pressure-lowering medicines, as interactions can occur. Avoid grapefruit, apple, and orange juice for at least 4 hours after taking the tablet. Also, avoid potassium-rich foods or supplements.

Storage

Store the medicine in a cool, dry place, protected from direct sunlight. Keep it in its original packaging and out of the sight and reach of children.

What is AMTAS M 25 MG TABLET used for?

AMTAS M 25 MG TABLET is primarily used to treat high blood pressure, also known as hypertension. It is also prescribed for chest pain related to heart conditions, such as angina pectoris, and in the management of coronary heart disease. This medication helps regulate issues related to your heart and blood vessels.

How does AMTAS M 25 MG TABLET work?

AMTAS M 25 MG TABLET contains two active ingredients: Amlodipine (5mg) and Metoprolol Succinate (25mg). Amlodipine, a calcium channel blocker, works by relaxing and widening your blood vessels, which reduces the resistance to blood flow and lowers blood pressure. Metoprolol Succinate, a beta-blocker, slows down your heart rate and reduces the strain on your heart. The combined action of these two medicines makes the heart more efficient at pumping blood throughout the body, thereby lowering blood pressure and alleviating chest pain.

What is the usual dosage for AMTAS M 25 MG TABLET?

The typical starting dose is usually one tablet (5mg Amlodipine and 25mg Metoprolol) once daily, often taken in the morning, with or without food. It is crucial to follow your doctor's prescribed dosage and timing precisely and not to exceed the recommended dose. Taking the tablet at the same time each day is advisable for consistent absorption and effectiveness.

What are the possible side effects of AMTAS M 25 MG TABLET?

Common side effects may include dizziness, fatigue, headache, nausea, abdominal pain, constipation, and swelling in the ankles and feet (peripheral oedema). Other potential side effects include a slower-than-normal heart rate (bradycardia), sleepiness, flushing, palpitations, breathlessness, muscle cramps, skin rash, and depression. Most side effects are temporary and usually resolve over time. However, if you experience any serious or persistent side effects, you should consult your doctor immediately.

Is AMTAS M 25 MG TABLET safe during pregnancy or breastfeeding?

Pregnancy: Caution is advised when taking AMTAS M 25 MG TABLET during pregnancy, and it is generally considered unsafe as it may have harmful effects on the fetus. It is essential to consult your doctor if you are pregnant or planning to become pregnant.

Breastfeeding: You should consult your doctor before taking this medication if you are breastfeeding. While some limited human data suggest the drug may not pose a significant risk to the baby, caution is generally advised, and it is considered probably unsafe to use during breastfeeding by some sources.

Can AMTAS M 25 MG TABLET be taken with other medications?

AMTAS M 25 MG TABLET can interact with several other medications. For example, medicines such as quinidine, fluoxetine, paroxetine, ketoconazole, itraconazole, and ritonavir can affect how AMTAS M 25 MG TABLET works in your body, potentially increasing its effects. Conversely, drugs like rifampin, phenytoin, and phenobarbital might decrease the concentration of amlodipine. Taking it with other blood pressure-lowering medicines, certain antifungals, antibiotics, or medications for irregular heartbeats may lead to an excessive drop in blood pressure or slow heart rate. You should avoid grapefruit or grapefruit juice as it can increase the concentration of the medicine and worsen side effects. It is crucial to inform your doctor about all the medicines, supplements, or herbal remedies you are currently taking to avoid potential interactions.

What precautions should be taken while taking AMTAS M 25 MG TABLET?

Do not stop taking AMTAS M 25 MG TABLET suddenly without consulting your doctor, as this can worsen your condition, potentially leading to severe chest pain, abnormal heart rhythms, or even a heart attack. If you experience dizziness or fatigue, avoid driving or operating heavy machinery. It is advisable to avoid alcohol consumption, as it can cause low blood pressure when taken with this medicine. Inform your doctor about any pre-existing health conditions such as diabetes, liver or kidney problems, heart conditions like heart failure or heart block, asthma, or other bronchospastic diseases. Regular monitoring of your blood pressure, kidney function, and electrolyte levels may be necessary during treatment. Also, avoid potassium-rich foods or supplements, as this medicine might raise potassium levels in the blood.

What happens if a dose of AMTAS M 25 MG TABLET is missed?

If you forget to take a dose of AMTAS M 25 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should AMTAS M 25 MG TABLET be stored?

AMTAS M 25 MG TABLET should be stored in a cool and dry place, protected from direct sunlight. Keep it in its original packaging, tightly closed, and out of the sight and reach of children and pets.