Clofranil Sr Tab

CLOFRANIL SR TAB by SUN PHARMA

CLOFRANIL SR Tablet is a sustained-release medication manufactured by Sun Pharmaceutical Industries Ltd.

• Name:

  • Brand Name: CLOFRANIL SR TAB
  • Common Name: Clomipramine Sustained Release Tablet

• Composition:

  • The active ingredient is Clomipramine (75 mg in CLOFRANIL SR 75mg Tablet).

• Uses: CLOFRANIL SR Tablet is a tricyclic antidepressant primarily used in adults. It is prescribed for:

  • Obsessive-Compulsive Disorder (OCD)
  • Depression
  • Panic and Anxiety Disorders
  • Phobias
  • Cataplexy associated with narcolepsy (a sleep disorder causing muscle weakness and uncontrollable daytime sleepiness)

• Dosage and Administration: CLOFRANIL SR Tablet should be taken as advised by a physician. It is typically taken orally, with food, and swallowed whole without crushing or chewing. For best results, it's often recommended to take it at the same time every day, and sometimes before bedtime due to potential drowsiness. Do not stop taking it suddenly, as this may lead to withdrawal symptoms.

• Side Effects: Common side effects include headache, dizziness, tiredness, nausea, vomiting, dry mouth, constipation, increased sweating, low sex drive, inability to maintain an erection, muscle twitching, problems in sleeping, and weight gain. Serious side effects can include serotonin syndrome (agitation, hallucinations, fast heartbeat), worsening depression, and suicidal thoughts.

• Precautions: CLOFRANIL SR is not recommended for pregnant or breastfeeding women unless considered necessary by a physician. Alcohol consumption should be avoided as it may increase side effects like drowsiness. Patients with liver, kidney, or heart problems, low blood pressure, glaucoma, or a history of seizures should use it with caution and inform their doctor. It should not be taken with MAOIs (Monoamine Oxidase Inhibitors) due to severe interaction risks. Driving or operating heavy machinery should be avoided if dizziness or drowsiness occurs.

• Storage: Store in a cool and dry place, away from direct sunlight, and out of the sight and reach of children. Typically, it should be stored below 30°C.

CLOFRANIL SR TAB, manufactured by SUN PHARMA VV, contains Clomipramine, a tricyclic antidepressant. It is primarily used to treat Obsessive-Compulsive Disorder (OCD), depression, panic disorder, and anxiety disorder. It can also be used in combination with other medicines to treat cataplexy, a disorder causing muscle weakness sometimes associated with narcolepsy.

Here are some frequently asked questions about CLOFRANIL SR TAB:

What is CLOFRANIL SR TAB used for?

CLOFRANIL SR TAB is primarily used to treat Obsessive-Compulsive Disorder (OCD), which involves persistent unwanted thoughts (obsessions) and repetitive behaviors (compulsions). It is also prescribed for depression, panic disorder, and anxiety disorder. Additionally, it may be used with other medications to manage cataplexy (muscle weakness) related to narcolepsy.

How does CLOFRANIL SR TAB work?

CLOFRANIL SR TAB contains Clomipramine, a tricyclic antidepressant. It works by increasing the activity of chemical messengers in the brain, specifically serotonin and noradrenaline, which play crucial roles in regulating mood, behavior, and emotions. By doing so, it helps relieve depression, lighten mood, and alleviate anxiety symptoms like fear and panic. For OCD, it helps reduce obsessive thoughts and compulsive behaviors by restoring chemical balance in the brain.

What is the usual dosage?

The dosage of CLOFRANIL SR TAB is determined by your doctor based on your age, health, and medical history. For adults with OCD, the typical starting dosage is 25 mg once daily, often at bedtime due to potential drowsiness. The dose may be gradually increased by your doctor over several weeks, up to a maximum of 250 mg daily. It's important to take the medicine at the same time each day for consistent effect.

What are the possible side effects?

Common side effects of CLOFRANIL SR TAB include dry mouth, constipation, nausea, dizziness, drowsiness, blurred vision, increased sweating, fatigue, tremor, indigestion, headache, and changes in appetite or weight (including weight gain). Some individuals may experience a sudden drop in blood pressure upon standing (orthostatic hypotension), an elevated heart rate, or sexual dysfunction. If these side effects persist or worsen, consult your doctor. More serious, but rare, side effects can include suicidal thoughts (especially in young adults), seizures, mania, heart rhythm changes, and serotonin syndrome.

Is it safe during pregnancy or breastfeeding?

CLOFRANIL SR TAB is generally not recommended during pregnancy, as animal studies have shown potential harm to the fetus. If you are pregnant or planning a pregnancy, consult your doctor. It is also generally advised to avoid breastfeeding while taking CLOFRANIL SR TAB, as it may be excreted in human milk and could cause adverse effects in the baby.

Can it be taken with other medications?

Avoid taking CLOFRANIL SR TAB with monoamine oxidase inhibitors (MAOIs) such as moclobemide, tranylcypromine, and phenelzine, as this combination can lead to severe adverse effects. There should be at least a 14-day gap between stopping an MAOI and starting CLOFRANIL SR TAB, and vice versa. It should also be used with caution with other medications that increase serotonin, as this could lead to serotonin syndrome. Always inform your doctor about all other medications you are currently taking.

What precautions should be taken?

Do not stop taking CLOFRANIL SR TAB suddenly, even if you feel better, as it can cause withdrawal symptoms or worsen your condition. Your doctor will guide you on how to gradually reduce the dose. It may cause dizziness and drowsiness, so avoid driving or operating heavy machinery until you know how it affects you. Alcohol consumption is not recommended as it can increase drowsiness and other side effects. Use with caution if you have heart conditions, liver problems, glaucoma, difficulty urinating, a history of seizures, or an overactive thyroid gland. Monitoring for suicidal thoughts, especially in young adults at the start of treatment or with dose changes, is important.

What happens if a dose is missed?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

How should it be stored?

CLOFRANIL SR TAB should be stored in a cool and dry place, away from direct sunlight, and out of the sight and reach of children. The recommended storage temperature is between 10ºC to 25ºC or below 30ºC.