Perinorm Cd Cap

PERINORM CD CAP

PERINORM CD CAP is a medication manufactured by IPCA LABORATORIES LTD, primarily used to manage various gastrointestinal issues.

• Name

  • Brand Name: PERINORM CD CAP
  • Common Name: Metoclopramide

• Composition

  • Each PERINORM CD CAP contains Metoclopramide (15 mg) as its active ingredient.

• Uses PERINORM CD CAP belongs to a class of medicines known as anti-emetics and prokinetic agents. It is prescribed for:

  • Managing nausea and vomiting, including those caused by chemotherapy, radiotherapy, or migraine.
  • Treating symptoms of gastroparesis, particularly diabetic gastroparesis (delayed gastric emptying in adults with diabetes).
  • Alleviating symptoms of Gastroesophageal Reflux Disease (GERD), heartburn, indigestion, and ulcers or sores in the esophagus.
  • Preventing post-operative nausea and vomiting.

• Dosage and Administration

  • PERINORM CD CAP should be taken orally as directed by a healthcare professional.
  • It is generally advised to take the capsule 30 minutes before meals and at bedtime.
  • Swallow the capsule whole with a glass of water; do not crush, chew, or break it to maintain its controlled-release properties.
  • The dosage and duration depend on the patient's condition and response to the medicine.

• Side Effects

  • Common Side Effects: Drowsiness, fatigue, restlessness, weakness, diarrhea, dizziness, stomach pain, altered mood, lack of concentration, and uncontrollable body movements (extrapyramidal symptoms like shaking, tics, muscle stiffness, or rigidity).
  • Serious Side Effects: Rare but potentially serious side effects include tardive dyskinesia (involuntary, repetitive movements with prolonged use), neuroleptic malignant syndrome (high fever, high blood pressure, convulsions), severe allergic reactions (itching, rash, swelling, breathing difficulties), hallucinations, low blood pressure, and slow heartbeats.

• Precautions

  • Do not take PERINORM CD CAP if you are allergic to Metoclopramide or any other ingredients.
  • It is contraindicated in patients with epilepsy, Parkinson's disease, pheochromocytoma (adrenal gland tumor), bleeding, obstruction, or tear in the stomach or gut, or a history of involuntary muscle spasms from previous medication.
  • Use with caution in pregnant women only if clearly advised by a doctor, and it is generally not recommended for breastfeeding women as it may pass into breast milk.
  • Avoid alcohol consumption as it may increase sedative effects.
  • Patients with liver, kidney, or heart diseases, diabetes, depression, or high blood pressure should consult their doctor before use.
  • This medicine may cause drowsiness or dizziness, so caution is advised while driving or operating machinery.
  • Prolonged use (more than 3 months) is not recommended due to the increased risk of tardive dyskinesia.
  • Abrupt discontinuation after prolonged use may lead to withdrawal symptoms.
  • Inform your doctor about all other medications you are taking, including herbal preparations and supplements, to avoid potential interactions, especially with medicines for Parkinson's disease (levodopa), anticholinergics, sedatives, or medications for mental health.
  • Not recommended for children below 1 year of age due to increased risk of uncontrollable movements.

• Storage

  • Store PERINORM CD CAP at room temperature, ideally between 20°C to 25°C or below 30°C.
  • Keep away from moisture, heat, and direct sunlight.
  • Do not freeze the medicine.
  • Keep out of sight and reach of children and pets.

What is Perinorm CD Capsule used for?

Perinorm CD Capsule is primarily used to manage symptoms of gastroparesis in adults, a condition characterized by delayed stomach emptying, which can lead to feelings of fullness, bloating, nausea, and vomiting. It is also used to treat gastroesophageal reflux disease (GERD), heartburn, indigestion, and to prevent nausea and vomiting caused by chemotherapy, radiotherapy, or migraines.

How does Perinorm CD Capsule work?

Perinorm CD Capsule contains metoclopramide (15mg), which works as a prokinetic agent. It primarily acts by blocking dopamine D2 and serotonin 5-HT3 receptors and stimulating serotonin 5-HT4 receptors in the brain and gut. This action increases the motility of the upper gastrointestinal tract, allowing food to move more easily through the stomach, and also helps in preventing nausea and vomiting by affecting the part of the brain that controls these sensations.

What is the usual dosage of Perinorm CD Capsule?

The dosage of Perinorm CD Capsule should be strictly as prescribed by your doctor. It is generally advised to take this medicine on an empty stomach, preferably about 30 minutes before meals and at bedtime. You should swallow the capsule whole with water and not crush, chew, or break it. Do not exceed the prescribed dose or duration of treatment.

What are the possible side effects of Perinorm CD Capsule?

Common side effects can include drowsiness, fatigue, restlessness, irritability, weakness, dizziness, headache, nausea, diarrhea, and abdominal discomfort. More serious, though less common, side effects can include extrapyramidal symptoms (unusual body movements or postures like tremors or slowed movements), galactorrhoea (unusual milk production), and with prolonged use, there is a risk of tardive dyskinesia (a movement disorder). If any side effects persist or worsen, consult your doctor.

Is Perinorm CD Capsule safe during pregnancy or breastfeeding?

During pregnancy, Perinorm CD Capsule should be used with caution and only if clearly advised by your doctor, who will weigh the benefits against the potential risks, especially towards the end of pregnancy. It is generally not recommended during breastfeeding because metoclopramide can pass into breast milk and may harm the breastfed baby. Always consult your doctor before taking this medicine if you are pregnant or breastfeeding.

Can Perinorm CD Capsule be taken with other medications?

Perinorm CD Capsule can interact with several other medications. It should not be used with medicines for Parkinson's disease (like levodopa), anticholinergics (used for stomach cramps), or dopaminergic agonists. Concomitant use with sedatives, hypnotics, or certain antidepressants (like fluoxetine and paroxetine) may increase its effects. Caution is also advised with medicines like digoxin, cyclosporine, and those affecting heart rhythm. Always inform your doctor about all other medications, herbal preparations, and supplements you are taking to avoid potential interactions.

What precautions should be taken while using Perinorm CD Capsule?

Avoid consuming alcohol while taking Perinorm CD Capsule, as it can increase drowsiness. Due to potential dizziness and sleepiness, avoid driving or operating machinery until you know how the medicine affects you. It is contraindicated if you are allergic to metoclopramide, have a history of tardive dyskinesia, gastrointestinal bleeding, obstruction or perforation, pheochromocytoma, epilepsy, or Parkinson's disease. Use with caution in patients with kidney or liver disease, heart conditions, or diabetes. Perinorm CD Capsule is generally not recommended for children under one year of age and prolonged use beyond 3 months should be avoided due to the risk of tardive dyskinesia.

What happens if a dose of Perinorm CD Capsule is missed?

If you miss a dose of Perinorm CD Capsule, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should Perinorm CD Capsule be stored?

Perinorm CD Capsule should be stored at room temperature, ideally between 20°C to 25°C, away from direct sunlight, heat, and moisture. Keep it out of sight and reach of children and pets. Do not use the medicine beyond its expiry date.