Percin 600 Mg (5 Tablet)

PERCIN 600 MG (5 TABLET) by LUPIN LTD

Name

Brand Name: PERCIN 600 MG Common Name: Prulifloxacin Tablet

Composition

PERCIN 600 MG Tablet contains Prulifloxacin 600 mg as its active ingredient. Prulifloxacin is a fluoroquinolone antibiotic.

Uses

PERCIN Tablet is an antibiotic used to manage various bacterial infections in the body. It is prescribed for conditions such as:

• Urinary tract infections (UTIs), including uncomplicated and complicated UTIs.
• Tonsillitis.
• Sinusitis.
• Respiratory tract infections, including acute exacerbation of chronic bronchitis and pneumonia.
• Skin and soft tissue infections.
• Infections of the nose and throat.
• Female genital organ infections.

It works by interfering with the enzyme DNA gyrase in bacteria, which is essential for their DNA synthesis, thus stopping their growth and multiplication.

Dosage and Administration

Percin 600 MG Tablet should be taken in the dose and duration advised by your doctor.

• Swallow the tablet whole with water; do not crush, chew, or break it.
• It is generally recommended to take it on an empty stomach for optimal absorption, ideally one hour before or two hours after a meal.
• To maintain a consistent level of medication, take it at evenly spaced intervals and at the same time each day.
• Complete the full course of treatment as prescribed, even if symptoms improve, to ensure all bacteria are killed and to prevent drug resistance.
• Avoid consuming dairy products (milk, cheese, curd, butter, paneer, ice cream) within 2 hours before or after taking Percin Tablet, as they can reduce its absorption.

Side Effects

Common side effects of Percin Tablet may include:

• Nausea.
• Vomiting.
• Stomach pain/abdominal pain.
• Headache.
• Dizziness.
• Diarrhea.
• Abnormal liver function tests.
• Skin rash.
• Photosensitivity of skin.
• Sleep disturbances.
• Muscle spasm.

Serious side effects, though rare, can include severe allergic reactions (rash, swelling of lips/face/tongue, difficulty breathing), tendinitis and tendon rupture (especially in elderly patients or those on corticosteroids), seizures (in patients with central nervous system disorders), and pseudomembranous colitis. If any persistent or severe side effects occur, seek immediate medical attention.

Precautions

• Pregnancy and Breastfeeding: Consult your doctor before taking Percin Tablet if you are pregnant, planning to become pregnant, or breastfeeding.
• Alcohol: Avoid consuming alcohol while taking this medicine as it may increase the risk of side effects.
• Medical Conditions: Inform your doctor if you have a history of liver problems, kidney issues, tendon disorders, myasthenia gravis, central nervous system disorders, or psychiatric disorders.
• Drug Interactions: Antacids, supplements containing iron or calcium, and certain other medications like probenecid, fenbufen, and theophylline can interact with Percin Tablet. Discuss all current medications, herbal preparations, and supplements with your doctor to avoid potential interactions. Take Percin at least 2 hours before or 4 hours after taking antacids or supplements containing calcium, iron, or zinc.
• Photosensitivity: Protect yourself from excessive sunlight to prevent phototoxicity.
• Pediatric Use: This medicine is generally not recommended for use in children and adolescents due to an increased risk of serious adverse effects.
• Elderly Patients: Use with caution in elderly patients due to an increased risk of tendinitis and tendon rupture.

Storage

Store Percin Tablet at a temperature below 30°C (or 25°C) in a cool and dry place. Keep it away from direct sunlight and moisture. Ensure it is out of the reach of children and pets.

What is PERCIN 600 MG used for?

PERCIN 600 MG (Prulifloxacin) is an antibiotic medication primarily used to treat various bacterial infections in different parts of the body. These include uncomplicated and complicated urinary tract infections (UTIs), tonsillitis, sinusitis, respiratory tract infections (such as acute exacerbation of chronic bronchitis and pneumonia), and infections of the skin, soft tissues, nose, throat, and female genital organs.

How does PERCIN 600 MG work?

PERCIN 600 MG contains Prulifloxacin, which belongs to the fluoroquinolone class of antibiotics. It works by interfering with essential bacterial enzymes called DNA gyrase and topoisomerase IV. These enzymes are crucial for bacterial DNA synthesis, replication, repair, and cell division. By inhibiting their activity, Prulifloxacin stops the growth and multiplication of bacteria, ultimately leading to their elimination from the body.

What is the usual dosage for PERCIN 600 MG?

The usual dosage for PERCIN 600 MG is one tablet (600 mg) taken orally once daily. The exact dosage and duration of treatment will depend on the specific type and severity of the infection and should be determined by your doctor. It is generally recommended to take the tablet on an empty stomach, ideally one hour before or two hours after a meal, and to swallow it whole with water without crushing or chewing.

What are the possible side effects of PERCIN 600 MG?

Common side effects of PERCIN 600 MG may include nausea, vomiting, stomach pain, headache, dizziness, diarrhea, abnormal liver function tests, and skin rash. More serious but less common side effects can include tendinitis and tendon rupture, especially in elderly patients or those also taking corticosteroids. Other potential side effects include photosensitivity (increased sensitivity to sunlight), sleep disturbances, hearing impairment, and muscle spasms. If you experience persistent or severe side effects, or signs of an allergic reaction, consult your doctor immediately.

Is PERCIN 600 MG safe during pregnancy or breastfeeding?

During Pregnancy: There is conflicting information regarding the safety of PERCIN 600 MG during pregnancy. Some sources state it is safe if prescribed by your doctor, while others recommend avoiding it or using with caution due to potential harmful effects on the fetus. Always consult your doctor if you are pregnant or planning to become pregnant to weigh the potential benefits against any risks.

During Breastfeeding: Similarly, information on breastfeeding is mixed. While some sources suggest it can be used if prescribed by a doctor, others advise against it, as a component of the medicine is known to be excreted in breast milk. It is crucial to consult your doctor to determine if the benefits outweigh any potential risks to your baby.

Can PERCIN 600 MG be taken with other medications?

PERCIN 600 MG can interact with certain medications. It may interact with antacids containing aluminum or magnesium hydroxide, anticoagulants like warfarin, nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen, proton pump inhibitors like omeprazole, pantoprazole, and cimetidine. Probenecid may also decrease the excretion of Percin. Always inform your doctor about all other medications, herbal preparations, and supplements you are currently taking to avoid possible drug interactions.

What precautions should be taken while taking PERCIN 600 MG?

It is important to complete the entire prescribed course of treatment, even if you start feeling better, to prevent the infection from returning or developing antibiotic resistance. Avoid skipping doses. Inform your doctor if you have a history of tendon disorders, myasthenia gravis, liver disease, kidney issues, central nervous system disorders (like seizures), or an irregular heartbeat. You should also avoid excessive exposure to sunlight or UV light due to increased photosensitivity while on this medication. Due to the potential for dizziness or confusion, exercise caution when driving or operating machinery. Avoid consuming dairy products (milk, cheese, curd, etc.) and calcium-fortified juices within two hours before or after taking Percin, as they can reduce its absorption. It is advisable to avoid alcohol consumption as it may increase the risk of side effects.

What happens if a dose of PERCIN 600 MG is missed?

If you miss a dose of PERCIN 600 MG, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one without consulting your doctor first.

How should PERCIN 600 MG be stored?

PERCIN 600 MG should be stored at a temperature below 30°C (or below 25°C), in a cool and dry place. Keep it away from direct sunlight and moisture. Ensure it is kept out of the reach of children and pets.