Nebistar Ln 5 Mg Tablet (10 Tab)

NEBISTAR LN 5 MG TABLET (10 TAB)

NEBISTAR LN 5 MG TABLET, manufactured by LUPIN LTD., is a combination medication primarily used for the management of hypertension (high blood pressure). It helps to control blood pressure when a single medication is not sufficient, thereby reducing the risk of serious cardiovascular events such as heart attack and stroke.

Composition

Each NEBISTAR LN 5 MG Tablet contains two active ingredients:

• Nebivolol (5 mg): A selective beta-1 receptor blocker with vasodilating properties. It works by slowing the heart rate and relaxing blood vessels, improving blood circulation and decreasing blood pressure.
• Cilnidipine (10 mg): A dihydropyridine calcium channel blocker. It inhibits the flow of calcium ions into vascular smooth muscle cells, causing blood vessels to relax and widen, which allows blood to flow more smoothly.

Uses

NEBISTAR LN 5 MG TABLET is prescribed for:

• Managing essential hypertension in adults.
• Lowering elevated blood pressure to a normal range.
• Reducing the risk of serious cardiovascular events such as heart attack and stroke.
• Improvement of heart function in patients with heart failure.
• Relieving chest pain (angina) and preventing cardiovascular complications related to hypertension.
• Regulating heart rate in conditions like tachycardia (abnormally fast heart rate).

Dosage and Administration

Typically, NEBISTAR LN 5 MG TABLET should be taken once daily, as directed by your doctor. It can be taken with or after a meal to help reduce side effects. Swallow the tablet whole with a glass of water; do not chew or crush it. It is important to take the medication at the same time each day to ensure consistent results and to continue taking it for the duration advised by your doctor, even if you feel well. Do not double a dose to make up for a missed one.

Side Effects

Common side effects may include:

• Headache
• Dizziness or lightheadedness
• Fatigue or tiredness
• Peripheral oedema (swelling in the feet and ankles)
• Nausea
• Diarrhoea or constipation
• Insomnia (difficulty sleeping)
• Slow heart rate (bradycardia)
• Flushing (sense of warmth in the face, ears, neck, and trunk)

Serious side effects are less common but require immediate medical attention if experienced:

• Severe allergic reactions (rash, itching, difficulty breathing)
• Fainting or severe dizziness
• Worsening heart failure or chest pain
• Breathing problems, especially in individuals with a history of asthma
• Signs of liver problems (e.g., yellowing of the skin or eyes)

Precautions

• Pregnancy and Breastfeeding: It should not be used during pregnancy unless clearly necessary and with medical supervision. It is not known if it passes into breast milk, so consult your doctor if breastfeeding.
• Alcohol: Caution is advised when consuming alcohol as it may worsen side effects like dizziness and fatigue and can lead to decreased blood pressure.
• Liver and Kidney Disease: Not recommended for severe liver diseases, and caution is advised for patients with kidney problems.
• Heart Conditions: Avoid if you have severe bradycardia, sick sinus syndrome, second/third-degree atrioventricular block (unless a pacemaker is in place), or acute heart failure.
• Diabetes: May mask symptoms of low blood sugar, requiring close monitoring of glucose levels.
• Asthma/COPD: Use with caution in patients with asthma or other respiratory conditions as Nebivolol may cause bronchospasm.
• Driving and Operating Machinery: May cause dizziness or sleepiness, so avoid driving or activities requiring alertness if affected.
• Drug Interactions: Inform your doctor about all medicines you are taking, especially other antihypertensives, heart medications (like digoxin), CYP2D6 inhibitors (e.g., quinidine, fluoxetine), and CYP3A4 inhibitors (e.g., itraconazole, ritonavir), as interactions can occur.

Storage

Store NEBISTAR LN 5 MG TABLET in a cool, dry place, away from direct sunlight, moisture, and heat. Ideally, store it at temperatures between 10°C to 25°C or below 30°C. Keep the medication in its original container, tightly closed, and out of reach of children and pets.

NEBISTAR LN 5 MG TABLET is a prescription medication primarily used to manage essential hypertension, also known as high blood pressure. It is a combination medicine containing two active ingredients: Cilnidipine and Nebivolol. This medication works to lower elevated blood pressure, thereby reducing the risk of serious cardiovascular events such as heart attack and stroke.

Here are some frequently asked questions about NEBISTAR LN 5 MG TABLET:

What is NEBISTAR LN 5 MG TABLET used for?

NEBISTAR LN 5 MG TABLET is used to treat essential hypertension (high blood pressure) in adults. By effectively lowering blood pressure, it helps reduce the risk of future cardiovascular complications like heart attacks, strokes, and kidney problems. It may also be used to improve heart function in patients with heart failure and relieve chest pain (angina).

How does NEBISTAR LN 5 MG TABLET work?

This medicine contains two active ingredients: Cilnidipine (10 mg) and Nebivolol (5 mg). Cilnidipine is a calcium channel blocker that relaxes and widens blood vessels, allowing blood to flow more smoothly. Nebivolol is a selective beta-1 receptor blocker that slows down the heart rate and relaxes blood vessels, which helps the heart pump blood more efficiently and lowers blood pressure. Their combined action helps to reduce the workload on the heart and control high blood pressure.

What is the usual dosage for NEBISTAR LN 5 MG TABLET?

The typical dosage is one tablet once daily, or as prescribed by your doctor. The tablet should be swallowed whole with a glass of water and not crushed or chewed. It can be taken with or without food, but it is recommended to take it at the same time each day to maintain consistent results and for better efficacy. Do not stop taking this medicine suddenly without consulting your doctor, as this can lead to an abrupt increase in blood pressure.

What are the possible side effects of NEBISTAR LN 5 MG TABLET?

Common side effects may include headache, dizziness, fatigue, nausea, diarrhea, insomnia, and peripheral edema (swelling in the feet and ankles). Other possible side effects are constipation, tingling sensations (paresthesia), slow heart rate, flushing, and low blood pressure. Most side effects are usually temporary and resolve over time. If you experience any serious or worsening side effects such as severe dizziness, fainting, chest pain, difficulty breathing, or signs of liver problems (e.g., yellowing of skin or eyes), seek immediate medical attention.

Is NEBISTAR LN 5 MG TABLET safe during pregnancy or breastfeeding?

Pregnancy: NEBISTAR LN 5 MG TABLET should generally not be used during pregnancy unless absolutely necessary and clearly advised by a doctor. If you are pregnant or planning to conceive, discuss this with your doctor before starting this medicine. Breastfeeding: It is not known if the medicine passes into breast milk. Nursing mothers should consult their doctor to understand the potential risks and benefits, as it may be advised to either stop the medicine or discontinue breastfeeding.

Can NEBISTAR LN 5 MG TABLET be taken with other medications?

It is important to inform your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements. NEBISTAR LN 5 MG TABLET can interact with certain medicines, potentially causing adverse effects. For example, taking it with other antihypertensives might lead to very low blood pressure, and combining it with some heart medications (like digoxin or certain anti-arrhythmics) could dangerously slow your heart rate. Medications for diabetes may have their effects masked, and some mental health drugs or anesthetics can also interact.

What precautions should be taken while taking NEBISTAR LN 5 MG TABLET?

You should not take this medicine if you have a known allergy to cilnidipine, nebivolol, or any other ingredients in the tablet. Exercise caution or avoid this medication if you have severe liver disease, severe kidney disease, certain heart conditions (e.g., very slow heart rate, heart block without a pacemaker, uncontrolled heart failure), untreated adrenal tumors (pheochromocytoma), or severe asthma/breathing problems, as it can worsen these conditions. If you have diabetes, closely monitor your blood glucose levels as this medicine may mask symptoms of low blood sugar. Alcohol consumption should be limited or avoided as it can worsen side effects like dizziness and fatigue. Since it may cause dizziness or tiredness, be cautious when driving or operating machinery until you know how the medicine affects you.

What happens if a dose of NEBISTAR LN 5 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one without consulting your doctor.

How should NEBISTAR LN 5 MG TABLET be stored?

Store NEBISTAR LN 5 MG TABLET in its original packaging in a cool, dry place, typically at a temperature not exceeding 30°C, away from direct sunlight and moisture. Ensure it is kept out of the reach and sight of children. Always check the expiry date and do not use the medicine beyond it.