Pregalin M Sr 75 Mg Tablet (15 Tab)

PREGALIN M SR 75 MG TABLET (15 TAB) by TORRENT PHARMACEUTICALS LTD.

Name:

• Brand Name: PREGALIN M SR 75 MG TABLET
• Common Name: Pregalin M SR 75 Tablet

Composition: PREGALIN M SR 75 MG TABLET contains two active ingredients:

• Pregabalin: 75 mg
• Methylcobalamin: 1500 mcg (1.5 mg), which is an active form of Vitamin B12.

Uses: This medication is primarily used for the treatment of neuropathic pain, which arises from nerve damage or nervous system malfunction. Conditions it is prescribed for include:

• Diabetic neuropathy
• Post-herpetic neuralgia (pain after shingles)
• Pain from spinal cord injuries
• Fibromyalgia symptoms like muscle pain, fatigue, and sleep problems It also helps calm overactive nerves, reduce pain signals, and support nerve repair and regeneration. Pregabalin, one of its components, is also an anticonvulsant used with other medicines to help control partial-onset seizures in epilepsy.

Dosage and Administration: The typical recommended dosage is one tablet twice a day, taken orally with water. It can be taken with or without food, though taking it with food might help reduce stomach upset. The sustained-release (SR) tablet should be swallowed whole and not crushed, chewed, or broken. For consistent medication levels, it is advised to take it at the same time each day. Do not stop the medication abruptly without consulting a doctor, as it can lead to withdrawal symptoms.

Side Effects: Common side effects may include:

• Dizziness, drowsiness, fatigue, blurred vision
• Dry mouth, constipation, weight gain
• Headache, nausea, vomiting, diarrhea
• Mood changes, decreased appetite, fluid retention
• Impaired balance or coordination, tremor, tingling and numbness in extremities Serious side effects requiring immediate medical attention include severe allergic reactions (e.g., skin rash, swelling of face/lips/throat, difficulty breathing) and symptoms of elevated creatine kinase (unexplained muscle pain, tenderness, weakness with fever).

Precautions:

• Avoid alcohol consumption as it can increase dizziness and drowsiness.
• Due to potential dizziness and drowsiness, avoid driving or operating machinery until you understand how the medication affects you.
• Inform your doctor if you have heart disease (may increase heart failure risk), liver or kidney disease (caution advised, dose adjustments may be needed), or a history of drug abuse.
• Not recommended for children and adolescents under 18 years of age.
• Use with caution in elderly patients due to an increased risk of accidental injury from dizziness or drowsiness.
• This medication is generally considered unsafe during pregnancy and possibly unsafe during breastfeeding; consult your doctor. Women of childbearing age should use effective contraception.
• Inform your doctor about all other medications, vitamins, and supplements you are taking to prevent potential drug interactions.

Storage: Store PREGALIN M SR 75 MG TABLET in a cool, dry place, protected from direct sunlight and moisture. Keep it out of the sight and reach of children.

PREGALIN M SR 75 MG TABLET is a combination medication containing Pregabalin (75 mg) and Methylcobalamin (1500 mcg). It is primarily used to treat neuropathic pain, which is pain caused by nerve damage.

What is PREGALIN M SR 75 MG TABLET used for?

PREGALIN M SR 75 MG TABLET is primarily used to treat neuropathic pain in adults. This includes pain caused by conditions such as diabetic neuropathy, post-herpetic neuralgia (pain after shingles), spinal cord injuries, and fibromyalgia. It may also help manage anxiety, general headaches, muscle discomfort, sleep disturbances, and promote mood stabilization.

How does PREGALIN M SR 75 MG TABLET work?

This medicine combines two active ingredients: Pregabalin and Methylcobalamin. Pregabalin is an anticonvulsant that works by decreasing the pain signals sent by damaged nerves in the body. It does this by modulating calcium channel activity in nerve cells, which reduces the release of certain chemicals that send pain signals. Methylcobalamin, a form of Vitamin B12, helps rejuvenate and protect damaged nerve cells by aiding in the production of myelin, the protective layer around nerve fibers. Together, these components help relieve nerve pain and improve nerve signal conduction.

What is the usual dosage for PREGALIN M SR 75 MG TABLET?

The usual dosage is typically one tablet twice a day, taken orally with water, or as advised by your doctor. It can be taken with or without food, preferably at bedtime. Swallow the tablet whole; do not crush, break, or chew it. To maintain consistent medicine levels in your body, it is advisable to take it at the same time each day. Your doctor will determine the exact dose and duration based on your specific condition and response to treatment.

What are the possible side effects of PREGALIN M SR 75 MG TABLET?

Common side effects include dizziness, drowsiness, headache, blurred vision, dry mouth, constipation, weight gain, nausea or vomiting, diarrhea, loss of appetite, fatigue, difficulty with concentration, and sweating. If any of these side effects persist or worsen, you should inform your doctor. More serious, though rare, side effects can include severe allergic reactions (like swelling of the face, lips, or throat), suicidal thoughts, or swelling of the limbs. Inform your doctor immediately if you experience any severe or unusual symptoms.

Is PREGALIN M SR 75 MG TABLET safe during pregnancy or breastfeeding?

Pregnancy: PREGALIN M SR 75 MG TABLET is generally advised to be used with caution during pregnancy, as there is limited data on its safety. It is considered a Category C medicine, meaning it should only be used if the potential benefit to the mother outweighs the potential risk to the fetus. Women of childbearing age should use effective contraception while taking this medicine. Always consult your doctor if you are pregnant or planning a pregnancy.

Breastfeeding: It is generally not recommended to breastfeed while taking PREGALIN M SR 75 MG TABLET, as its components may pass into breast milk and potentially harm the infant. Your doctor will assess whether to discontinue breastfeeding or the medication based on the benefits and risks.

Can PREGALIN M SR 75 MG TABLET be taken with other medications?

It's crucial to inform your doctor about all medicines, including prescribed, over-the-counter, herbal remedies, and supplements you are currently taking or have recently taken. PREGALIN M SR 75 MG TABLET can interact with certain medications. For example, it may increase the risk of drowsiness and other side effects if taken with central nervous system (CNS) depressants like opioids, benzodiazepines, or alcohol. It may also interact with some antihypertensives (blood pressure-lowering medicines) or ACE inhibitors, potentially affecting blood pressure or increasing the risk of angioedema.

What precautions should be taken while using PREGALIN M SR 75 MG TABLET?

• Allergies: Do not take this medicine if you are allergic to Pregabalin, Methylcobalamin, or any other ingredients.
• Medical Conditions: Inform your doctor if you have a history of heart disease (especially heart failure), liver or kidney problems, a history of angioedema, respiratory depression, seizures, alcoholism, or drug abuse. Dose adjustments may be necessary for patients with kidney disease.
• Driving and Operating Machinery: This medicine can cause dizziness, drowsiness, and blurred vision, which may impair your ability to drive or operate heavy machinery. Avoid these activities until you understand how the medication affects you.
• Alcohol Consumption: Avoid consuming alcohol as it can intensify side effects like dizziness and drowsiness.
• Sudden Discontinuation: Do not stop taking PREGALIN M SR 75 MG TABLET abruptly without consulting your doctor, as this can lead to withdrawal symptoms such as anxiety, difficulty sleeping, nausea, pain, and sweating. Your doctor will likely recommend gradually reducing the dose.
• Weight Gain: Weight gain can occur with this medicine. Maintaining a balanced diet and regular exercise may help manage this.
• Mood Changes: Inform your doctor if you experience any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.
• Age: It is not recommended for individuals under 18 years of age. Elderly patients should use it with caution due to an increased risk of accidental injury from dizziness or drowsiness.

What happens if a dose is missed?

If you miss a dose of PREGALIN M SR 75 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are unsure, consult your doctor.

How should PREGALIN M SR 75 MG TABLET be stored?

Store PREGALIN M SR 75 MG TABLET in a cool and dry place, away from direct sunlight and moisture. It should be kept out of the sight and reach of children. Store below 25°C to 30°C and do not freeze.