Urihold S 25mg Tab

URIHOLD S 25MG Tablet

URIHOLD S 25MG Tablet is a combination medication designed to manage the symptoms of overactive bladder (OAB). It helps to improve bladder control and reduce urinary incontinence in affected individuals.

• Name: URIHOLD S 25MG Tablet

  • Brand Name: URIHOLD S 25MG (by ARISTO PHARMA)
  • Common Name: Solifenacin and Mirabegron (combination)

• Composition: Each tablet contains Mirabegron (25 mg) and Solifenacin (5 mg).

• Uses: URIHOLD S 25MG Tablet is prescribed for the treatment of overactive bladder (OAB) symptoms. These symptoms include:

  • Frequent urination
  • Urgent need to urinate
  • Involuntary loss of urine (urinary incontinence)
  • Urinary urgency

• Dosage and Administration:

  • URIHOLD S 25MG is typically taken orally once daily, as directed by a doctor.
  • It can be taken with or without food.
  • The tablet should be swallowed whole with a full glass of water. Do not crush, chew, or break the tablet.
  • For optimal benefits, it is recommended to take the medication at the same time each day.

• Side Effects:

  • Common Side Effects: Headache, constipation, dizziness, dry mouth, and blurred vision. Other commonly reported side effects include nausea, abdominal fullness, stomach pain, burping, heartburn, fast heart rate, and urinary tract infection.
  • Serious Side Effects: Allergic reactions (such as rash, itching, swelling, severe dizziness, or difficulty breathing) are rare but possible and require immediate medical attention.

• Precautions:

  • Pregnancy and Breastfeeding: Not recommended for use during pregnancy or while breastfeeding. Consult a doctor for alternative treatments.
  • Alcohol Consumption: It is advisable to avoid or limit alcohol, as it may increase the risk of side effects like drowsiness or dizziness.
  • Elderly Patients: Use with caution, as elderly patients may be more sensitive to side effects; dosage adjustments may be necessary.
  • Children: Not recommended for individuals under 18 years of age.
  • Medical Conditions: Inform your doctor if you have kidney problems, liver problems, urinary retention, stomach or intestinal blockage, glaucoma, or heart conditions (e.g., uncontrolled high blood pressure, abnormal heart rhythm), as these may require dosage adjustments or careful monitoring.
  • Drug Interactions: Inform your doctor about all other medications, including prescription, over-the-counter drugs, herbal supplements, and vitamins, to avoid potential drug interactions.

• Storage: Store at room temperature (20-25°C) and protect from moisture and light. Keep out of reach of children.

What is URIHOLD S 25MG TAB used for?

URIHOLD S 25MG TAB is primarily used to manage the symptoms of an overactive bladder (OAB). These symptoms include a sudden, strong urge to urinate (urgency), frequent urination, and involuntary leakage of urine (urinary incontinence). It can also be used to treat neurogenic detrusor overactivity (NDO).

How does URIHOLD S 25MG TAB work?

This medicine contains two active ingredients: Mirabegron (25 mg) and Solifenacin (5 mg).

• Mirabegron works as a beta-3 adrenergic agonist. It activates beta-3 receptors in the bladder muscles, causing them to relax and increasing the bladder's capacity to store urine.
• Solifenacin is an anticholinergic (antimuscarinic) agent. It blocks specific receptors (M3 muscarinic receptors) in the bladder muscles, which helps to reduce involuntary bladder contractions, thereby decreasing the sense of urgency and frequency of urination. Together, these components provide a dual action to improve bladder control.

What is the usual dosage for URIHOLD S 25MG TAB?

The usual dosage is one tablet taken once daily, with or without food. It is crucial to swallow the tablet whole with a glass of water and not to crush, chew, or break it, as it is typically an extended-release formulation. Your doctor will determine the appropriate dose and duration of treatment based on your individual condition, age, and body weight.

What are the possible side effects of URIHOLD S 25MG TAB?

Common side effects may include dry mouth, constipation, headache, dizziness, blurred vision, nausea, abdominal fullness, stomach pain, burping, heartburn, increased heart rate, urinary tract infection, and nasopharyngitis (inflammation of the throat and nasal passages). More serious, though less common, side effects can include urinary retention (difficulty emptying the bladder), QT prolongation (a heart rhythm disorder), hallucinations, worsening of narrow-angle glaucoma, and severe allergic reactions such as angioedema (swelling of the face, lips, tongue, or throat) or anaphylaxis. If you experience severe or persistent side effects, contact your doctor immediately.

Is URIHOLD S 25MG TAB safe during pregnancy or breastfeeding?

Pregnancy: URIHOLD S 25MG TAB is generally not recommended during pregnancy unless your doctor considers it absolutely necessary, due to limited information on its safety during this period. Caution is advised. Breastfeeding: It is not recommended for use while breastfeeding as the medication may pass into breast milk. Always consult your doctor for advice on suitable alternatives if you are pregnant or breastfeeding.

Can URIHOLD S 25MG TAB be taken with other medications?

Yes, but it's important to inform your doctor about all other medications you are currently taking, including prescription drugs, over-the-counter medicines, herbal supplements, and vitamins, to avoid potential drug interactions. Significant interactions can occur with:

• Certain antifungal medications (e.g., ketoconazole)
• Antiviral medications (e.g., ritonavir)
• Some blood pressure medications (e.g., verapamil)
• Other anticholinergic drugs (e.g., oxybutynin), which may increase side effects like dry mouth and constipation.
• Cardiac medications (e.g., digoxin), as they may alter effectiveness or increase side effects.
• Blood thinners (e.g., warfarin), which could affect blood clotting.
• Medications that can prolong the QT interval (a heart rhythm measure).

What precautions should be taken while using URIHOLD S 25MG TAB?

Before taking URIHOLD S 25MG TAB, inform your doctor if you have liver, kidney, or heart problems, glaucoma, severe constipation, stomach problems (like gastric retention or bowel blockage), or a history of urinary retention or urinary tract infections.

• Avoid driving or operating heavy machinery if the medication causes dizziness, drowsiness, or blurred vision.
• Be cautious in hot weather or during physical activity, as this medicine can affect your body's ability to cool itself, potentially leading to heat exhaustion or heatstroke.
• Limit or avoid alcohol and caffeine consumption, as these can worsen overactive bladder symptoms or increase side effects.
• Do not stop taking the medication abruptly without consulting your doctor, as your symptoms may return.

What happens if a dose of URIHOLD S 25MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should URIHOLD S 25MG TAB be stored?

Store URIHOLD S 25MG TAB at room temperature, generally not exceeding 30°C (or 20-25°C). Keep the medicine in its original packaging to protect it from moisture and direct sunlight, and always keep it out of the reach of children.