Goodflo 150 Mg Capsule (10 Cap)

GOODFLO 150 MG CAPSULE (10 CAP) by LUPIN LTD.

GOODFLO 150 MG Capsule is an anticoagulant medication designed to prevent and treat the formation of blood clots. It is manufactured by Lupin Ltd.

Composition

• Active Ingredient: Dabigatran Etexilate (150 mg).

Uses

GOODFLO 150 MG Capsule is primarily used as a blood thinner to:

• Prevent and treat deep vein thrombosis (DVT) and pulmonary embolism (PE).
• Reduce the risk of stroke and systemic embolism in adult patients with irregular heart rhythms (atrial fibrillation).
• Prevent blood clot formation in patients who have undergone knee or hip replacement surgeries.
• Manage and prevent recurrent DVT and PE.

Dosage and Administration

The typical recommended dosage for most adults is 150 mg taken orally twice daily, approximately 12 hours apart. The capsules should be swallowed whole with a glass of water, and should not be crushed or chewed. GOODFLO can be taken with or without food, but it is advisable to take it at the same time each day to maintain a consistent level of medication in the system. Do not discontinue or alter the dosage without consulting a doctor, as this could increase the risk of serious complications.

Side Effects

Common side effects may include:

• Stomach upset, abdominal pain, dyspepsia.
• Nausea, diarrhea.
• Increased bleeding tendency, such as nosebleeds, skin bleeding, or easy bruising.
• Anemia (low number of red blood cells).
• Gastrointestinal bleeding.

Serious side effects can include bleeding from various parts of the body, headaches, seizures, allergic reactions, changes in eyesight, and fatigue. Promptly inform your doctor if you experience any concerning symptoms.

Precautions

• Contraindications: GOODFLO 150 MG Capsule is contraindicated in individuals with severe kidney or liver problems, active bleeding, or those taking other medications to reduce blood clotting (e.g., warfarin, rivaroxaban, apixaban, heparin).
• Bleeding Risk: This medication increases the risk of bleeding. Caution should be exercised during activities that may cause injury or bleeding.
• Drug Interactions: Inform your doctor about all medicines, supplements, or herbals you are taking. Concomitant use with certain oral antifungals (ketoconazole, posaconazole), cyclosporin, dronedarone, antiviral medicines (glecaprevir, pibrentasvir), NSAIDs (ibuprofen, naproxen), antiplatelet drugs (aspirin, clopidogrel), and other anticoagulants may increase the risk of bleeding. Caution is also advised with verapamil, amiodarone, quinidine, clarithromycin, rifampicin, carbamazepine, phenytoin, tacrolimus, and digoxin.
• Pregnancy and Breastfeeding: Not recommended for use during pregnancy or breastfeeding unless advised by a doctor. Women of childbearing age should avoid becoming pregnant while taking this medicine.
• Alcohol: Heavy alcohol consumption can increase the anticoagulant action and bleeding risk. Discuss alcohol intake with your doctor.
• Surgical Procedures: You may be asked to temporarily stop taking this medicine before surgery or dental treatment.
• Liver and Kidney Function: Caution is advised in patients with liver disease or reduced kidney function.

Storage

Store GOODFLO 150 MG Capsule at room temperature, between 15°C to 30°C (59°F to 86°F). Keep the medicine in its original packaging in a dry place, protected from moisture. Close the bottle tightly after use and keep it out of the reach of children. Once opened, the bottle should be used within 4 months; discard safely if unused beyond this period.

GOODFLO 150 MG CAPSULE: Frequently Asked Questions

GOODFLO 150 MG CAPSULE, manufactured by LUPIN LTD., contains Dabigatran Etexilate as its active ingredient. It is an anticoagulant, commonly referred to as a blood thinner, used to prevent and treat blood clots.

What is GOODFLO 150 MG CAPSULE used for?

GOODFLO 150 MG CAPSULE is primarily used to prevent and treat blood clots. This includes treating deep vein thrombosis (DVT) and pulmonary embolism (PE), and preventing their recurrence. It is also used to prevent blood clots in the brain (stroke) and other blood vessels in adults with atrial fibrillation (an irregular heartbeat). Additionally, it can be prescribed to prevent clot formation after orthopedic surgeries like knee or hip replacement. In children, it is used to treat and prevent blood clots.

How does GOODFLO 150 MG CAPSULE work?

GOODFLO 150 MG CAPSULE contains Dabigatran Etexilate, which is a direct thrombin inhibitor. It works by blocking the action of thrombin, a key enzyme involved in the blood clotting process. By inhibiting thrombin, it prevents the conversion of fibrinogen to fibrin, thereby reducing the formation of blood clots and increasing clotting time. This action allows blood to flow more freely throughout the body.

What is the usual dosage of GOODFLO 150 MG CAPSULE?

The usual adult starting dose for conditions like atrial fibrillation is typically 150 mg taken twice daily. For postoperative venous thromboembolism prevention, an initial dose of 110 mg is given within 1-4 hours after surgery, followed by 220 mg once daily. Dosage can vary based on individual health conditions, kidney function, age (e.g., over 75 years), and concurrent medications. Always follow your doctor's specific dosing instructions.

What are the possible side effects of GOODFLO 150 MG CAPSULE?

The most common side effects include bleeding or bruising, stomach ache, feeling sick (nausea), indigestion, and loose motions (diarrhea). Other potential side effects can include anemia (low red blood cell count), gastrointestinal bleeding, nosebleeds, and skin bleeding. More serious but less common side effects can include headaches, seizures, allergic reactions, changes in eyesight, and tiredness. If any side effects persist or worsen, it is important to consult your doctor.

Is GOODFLO 150 MG CAPSULE safe during pregnancy or breastfeeding?

GOODFLO 150 MG CAPSULE is generally not recommended during pregnancy as its effects on pregnancy and the growing child are not well known. Women of childbearing age should avoid becoming pregnant while taking this medicine. It is also not recommended for use while breastfeeding, as it is unknown whether the medication passes into human breast milk. Always consult your doctor for personalized advice if you are pregnant, planning pregnancy, or breastfeeding.

Can GOODFLO 150 MG CAPSULE be taken with other medications?

GOODFLO 150 MG CAPSULE can interact with other medications, potentially increasing the risk of bleeding. Certain medicines should not be taken with Goodflo Capsule, including oral antifungals (e.g., ketoconazole, posaconazole), cyclosporin, dronedarone, and antiviral medicines (e.g., glecaprevir and pibrentasvir). Concomitant use with other anticoagulants (e.g., warfarin, rivaroxaban, apixaban, heparin), NSAIDs (e.g., ibuprofen, naproxen), and anti-platelet drugs (e.g., aspirin, clopidogrel) can significantly increase the risk of bleeding. It is crucial to inform your doctor about all medicines, supplements, or herbal products you are taking to prevent potential interactions.

What precautions should be taken with GOODFLO 150 MG CAPSULE?

Several precautions should be taken while on this medication. You should not take GOODFLO 150 MG CAPSULE if you have a known allergy to dabigatran etexilate or any of its ingredients, have reduced kidney or liver function, a bleeding disorder, or an existing condition that increases the risk of bleeding (e.g., stomach ulcer, recent injury or surgery). Heavy alcohol consumption can also increase the risk of bleeding. Before any surgery or dental treatment, you may be asked to temporarily stop taking GOODFLO 150 MG CAPSULE to avoid bleeding risks; follow your doctor's instructions carefully. Regular blood tests to check kidney function may be performed before and during treatment. It is important not to stop taking this medicine or miss a dose without consulting your doctor, as this can increase the risk of clot formation, stroke, or heart attack.

What happens if a dose is missed?

If you miss a dose of GOODFLO 150 MG CAPSULE, take it as soon as you remember on the same day. However, if it is almost time for your next dose (typically less than 6 hours away), skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. Missing doses can increase the risk of clot formation. Always consult your doctor for specific advice on missed doses.

How should GOODFLO 150 MG CAPSULE be stored?

GOODFLO 150 MG CAPSULE should be stored in its original package to protect it from moisture, at room temperature (between 15°C to 30°C or 59°F to 86°F) in a dry place. Keep the bottle tightly closed after use and out of the reach of children. Once the bottle is opened, the capsules should be used within 4 months; discard any unused capsules safely after this period.