Afogatran 75 Cap

AFOGATRAN 75 CAP by TORRENT PHARMACEUTICALS LTD

Name: AFOGATRAN 75 CAP (also known as Afogatran 75mg Capsule).

Composition: Each capsule contains Dabigatran Etexilate (75mg). This active ingredient is a direct thrombin inhibitor, functioning as an anticoagulant or "blood thinner."

Uses: AFOGATRAN 75 CAP is primarily used to prevent and manage blood clots, reducing the risk of life-threatening conditions such as stroke and heart attack. It is particularly beneficial for adults with non-valvular atrial fibrillation (irregular heart rhythm) to prevent stroke and systemic embolism. Additionally, it is prescribed for managing and preventing the recurrence of deep vein thrombosis (DVT) and pulmonary embolism (PE), and for reducing the risk of venous thromboembolic events (VTE) in patients who have undergone hip or knee replacement surgery.

Dosage and Administration: Take AFOGATRAN 75 CAP exactly as advised by your doctor, typically twice daily at the same time each day, with approximately 12 hours between doses. It can be taken with or without food. Swallow the capsule whole with water; do not break, chew, or open it. Do not stop taking or change the dosage without consulting your doctor, as this could increase the risk of serious complications.

Side Effects: Common side effects include bleeding complications (e.g., gum bleeding, nosebleeds, prolonged bleeding from cuts, bruising, gastrointestinal bleeding), anemia (tiredness, shortness of breath), and gastrointestinal symptoms such as stomach upset, pain, diarrhea, nausea, dyspepsia, and vomiting. Allergic reactions (rash, itching, difficulty breathing) are also possible. Report any unusual bruising or bleeding to your doctor immediately.

Precautions:

• Contraindications: Do not take if you have a known allergy to dabigatran etexilate, active pathological bleeding, severe renal impairment, or mechanical prosthetic heart valves.
• General Warnings: Consult your doctor if you are pregnant or breastfeeding, have severe kidney or liver problems, a stomach ulcer, high blood pressure, or other bleeding disorders.
• Interactions: Inform your doctor about all medications you are taking, as AFOGATRAN 75 CAP can interact with antifungals (e.g., ketoconazole), anticonvulsants (e.g., carbamazepine, phenytoin), and other anticoagulants or antiplatelet agents (e.g., warfarin, aspirin).
• Alcohol: Avoid alcohol consumption as it may increase the risk of bleeding.
• Surgery: You may need to temporarily stop this medicine before surgery or dental procedures; your doctor will advise.
• Children: Not recommended for children under 18 years of age.

Storage: Store AFOGATRAN 75 CAP at room temperature, between 15°C to 30°C (59°F to 86°F), in a dry place, away from direct sunlight and moisture. Keep it in the original package, tightly sealed, and out of reach of children. If the bottle is opened, use the medication within 4 months.

Here are the most frequently asked questions about AFOGATRAN 75 CAP:

What is AFOGATRAN 75 CAP used for?

AFOGATRAN 75 CAP is an anticoagulant (blood thinner) primarily used to prevent and treat blood clots. It helps reduce the risk of stroke and heart attack in patients with irregular heart rhythms (atrial fibrillation). It is also used to prevent and treat deep vein thrombosis (blood clots in leg veins) and pulmonary embolism (blood clots in the lungs), and to reduce clot formation in individuals who have undergone knee or hip replacement surgeries.

How does AFOGATRAN 75 CAP work?

AFOGATRAN 75 CAP contains Dabigatran Etexilate, which works by inhibiting thrombin, a critical protein involved in blood clot formation. By blocking thrombin, it prevents the conversion of fibrinogen to fibrin, an essential step in forming blood clots. This action helps maintain blood flow and reduces the risk of harmful clots developing in the veins or arteries.

What is the usual dosage for AFOGATRAN 75 CAP?

AFOGATRAN 75 CAP is usually taken twice daily, with or without food. It's important to take it at the same time each day, as prescribed by your doctor. Do not stop taking it or change the dose without your doctor's guidance.

What are the possible side effects of AFOGATRAN 75 CAP?

Common side effects include bleeding (such as nosebleeds, bleeding gums, or prolonged bleeding from cuts), anemia (low red blood cell count), nausea, stomach pain, vomiting, indigestion, and diarrhea. If you experience persistent or severe side effects, or any unusual bleeding, you should consult your doctor immediately.

Is AFOGATRAN 75 CAP safe during pregnancy or breastfeeding?

AFOGATRAN 75 CAP is generally not recommended during pregnancy, as animal studies have shown harmful effects on the developing baby, and human studies are limited. It is also probably unsafe during breastfeeding as the drug may pass into breast milk and harm the baby. It is advised to consult your doctor before using this medicine if you are pregnant or breastfeeding.

Can AFOGATRAN 75 CAP be taken with other medications?

AFOGATRAN 75 CAP can interact with several medications. Concomitant use with other anticoagulants or antiplatelet agents (like aspirin or clopidogrel) can increase the risk of bleeding. Certain antifungals (e.g., ketoconazole, posaconazole), some antibiotics (e.g., clarithromycin), anticonvulsants (e.g., carbamazepine, phenytoin), and medicines for heart conditions (e.g., amiodarone, quinidine) may also interact. Always inform your doctor about all medicines, supplements, or herbal products you are taking.

What precautions should be taken while using AFOGATRAN 75 CAP?

Inform your doctor if you have an artificial heart valve, stomach ulcer, kidney or liver problems, high blood pressure, or bleeding disorders. Avoid alcohol consumption as it may increase the risk of stomach bleeding. You should also inform your doctor if you are scheduled for surgery or dental treatment, as you may need to temporarily stop taking the medication. Do not stop taking the medicine on your own, as it can increase the risk of heart attack and stroke.

What happens if a dose of AFOGATRAN 75 CAP is missed?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one. Consult your doctor if you frequently miss doses.

How should AFOGATRAN 75 CAP be stored?

AFOGATRAN 75 CAP should be stored in a cool and dry place, away from direct sunlight and moisture, at room temperature (between 15°C to 30°C). Keep the bottle tightly sealed and out of the sight and reach of children. Once opened, the medicine should generally be used within four months; any unused portion after this time should be discarded safely.