Monadine

Monadine Tablet, manufactured by FRANCO-INDIAN PHARMACEUTICALS PVT LTD, is an anti-allergic medication designed to provide relief from various allergy symptoms.

Composition

Monadine Tablet contains a combination of two active ingredients:

• Montelukast Sodium I.P. equivalent to Montelukast 10 mg
• Fexofenadine Hydrochloride I.P. 120 mg

Montelukast acts as a leukotriene receptor antagonist, blocking chemicals that cause inflammation in the airways, while Fexofenadine is an antihistamine that inhibits histamine, a substance responsible for allergic reactions.

Uses

Monadine Tablet is primarily used to treat allergy-related conditions in adults and adolescents aged 15 years and above. These include:

• Allergic rhinitis, including seasonal allergies (hay fever) and perennial allergies
• Symptoms such as sneezing, runny nose, nasal congestion, itchy or watery eyes, and itchy or runny nose
• Chronic hives (urticaria) by relieving itching and swelling
• Allergic rhinitis associated with asthma.

Dosage and Administration

The typical dosage of Monadine Tablet is once daily, or as directed by a doctor. The tablet should be swallowed whole with water and not crushed or chewed. It can be taken with or without food, but it is advisable to take it at the same time each day for optimal results.

Side Effects

Common side effects may include:

• Headache
• Dizziness
• Drowsiness
• Nausea and vomiting
• Diarrhea
• Fatigue
• Upper respiratory tract infections
• Skin rash

More serious, though rare, side effects can include chest tightness or difficulty breathing. If any side effects persist or worsen, medical consultation is advised.

Precautions

• Pregnancy and Breastfeeding: Use during pregnancy should be only when necessary and under medical advice. It is considered safe during breastfeeding as it appears in breast milk in small amounts.
• Alcohol: Avoid consuming alcohol as it may intensify side effects such as dizziness and drowsiness.
• Liver and Kidney Impairment: Caution is advised for patients with liver or kidney problems.
• Driving and Operating Machinery: Due to potential dizziness and drowsiness, avoid driving or operating heavy machinery until you know how the medicine affects you.
• Drug Interactions: Antacids containing magnesium or aluminum hydroxide, certain antibiotics (e.g., erythromycin), antifungals (e.g., ketoconazole), and strong CYP3A4 inhibitors may interact with Monadine.
• Food Interactions: Avoid grapefruit juice as it can increase the level of montelukast in the body, potentially causing adverse side effects. Do not take it with other fruit juices (such as apple or orange) as they might reduce its effectiveness.
• Allergy Tests: Stop taking Monadine at least three days before an allergy test, as it can affect the test results.

Storage

Store Monadine Tablet at room temperature, ideally below 25°C or 30°C, away from direct light and moisture. Keep it securely out of reach of children and pets. Always check the expiry date before use.

Frequently Asked Questions about MONADINE Tablet

MONADINE Tablet, manufactured by FRANCO-INDIAN PHARMACEUTICALS PVT LTD, is a medication used to manage allergic conditions. Here are some frequently asked questions about this medicine:

What is MONADINE Tablet used for?

MONADINE Tablet is primarily used to treat allergic rhinitis, which includes both seasonal allergies (hay fever) and perennial allergies that can occur year-round. It helps alleviate symptoms such as sneezing, runny nose, stuffy nose, nasal congestion, and itchy or watery eyes. This medicine can also be beneficial in managing chronic hives (urticaria) by relieving associated itching and swelling.

How does MONADINE Tablet work?

MONADINE Tablet is a combination of two active ingredients: Fexofenadine and Montelukast. Fexofenadine is an antihistamine that works by blocking the action of histamine, a natural substance in the body responsible for triggering allergic symptoms like itching, redness, and swelling. Montelukast is a leukotriene receptor antagonist that blocks the action of leukotrienes, which are inflammatory chemicals released during an allergic reaction. By doing so, Montelukast helps reduce inflammation in the airways, further easing allergy symptoms.

What is the usual dosage for MONADINE Tablet?

MONADINE Tablet typically contains Montelukast 10mg and Fexofenadine 120mg. The exact dosage and duration of treatment should be strictly followed as prescribed by your doctor. It can be taken with or without food, and it is advisable to take it at the same time each day to maintain a consistent level of the medication in your body. This medicine is indicated for adults and adolescents aged 15 years and above.

What are the possible side effects of MONADINE Tablet?

Common side effects of MONADINE Tablet include nausea, diarrhea, vomiting, flu-like symptoms, headache, drowsiness, dizziness, upper respiratory tract infection, increased transaminase levels in the blood, and skin rash. These side effects are usually mild and temporary, often resolving as your body adjusts to the medication. If any side effects persist or cause concern, it is important to consult your doctor immediately.

Is MONADINE Tablet safe during pregnancy or breastfeeding?

During Pregnancy: MONADINE Tablet should be used during pregnancy only if clearly advised by your doctor and when the potential benefits outweigh the risks. There is limited information on its safety in humans, and animal studies have shown potential harmful effects on the developing baby. During Breastfeeding: MONADINE Tablet is generally not recommended for use while breastfeeding due to limited information on its effects. While some sources suggest it may be safe if prescribed as it appears in breast milk in small amounts not known to harm the baby, it is always best to consult your doctor before taking this medicine if you are breastfeeding.

Can MONADINE Tablet be taken with other medications?

MONADINE Tablet can interact with certain medications. For example:

• Antacids: Medicines containing magnesium or aluminium hydroxide can reduce the absorption of fexofenadine, making MONADINE less effective. It is recommended to maintain a minimum interval of 2 hours between taking MONADINE and antacids.
• Antibiotics and Antifungals: Medications like erythromycin (an antibiotic) and ketoconazole (an antifungal) can increase the levels of fexofenadine in your body, potentially leading to adverse effects.
• Other Medications: Use with caution if you are taking phenobarbital, phenytoin, rifampin, or gemfibrozil. Inform your doctor about all other medications you are taking, including over-the-counter and herbal preparations, to avoid potential interactions.

What precautions should be taken while using MONADINE Tablet?

• Always follow the dosage and duration prescribed by your doctor. Do not stop treatment prematurely, as this can lead to symptom recurrence or worsening of your condition.
• Inform your doctor about any pre-existing medical conditions, especially liver or kidney problems, or pulmonary disorders like asthma.
• If you experience dizziness or drowsiness, avoid driving or operating heavy machinery until you know how the medicine affects you.
• Avoid consuming alcohol while taking MONADINE Tablet, as it can intensify side effects such as dizziness and drowsiness.
• Do not take MONADINE Tablet with fruit juices like grapefruit, orange, or apple, as they may reduce its effectiveness.
• This medicine is not meant to manage acute asthma attacks.
• Stop taking MONADINE Tablet at least three days before undergoing an allergy test, as it can interfere with the test results.

What happens if a dose of MONADINE Tablet is missed?

If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should MONADINE Tablet be stored?

MONADINE Tablet should be stored at room temperature, ideally below 25°C or 30°C. Keep the medicine away from direct light and moisture, and ensure it is securely out of the reach of children and pets.