Vildamac Dp 100 Mg/10 Mg Tablet (10 Tab)

VILDAMAC DP 100 MG/10 MG TABLET

VILDAMAC DP 100 MG/10 MG TABLET is a combination medication prescribed for the management of type 2 diabetes mellitus. It is manufactured by Macleods Pharmaceuticals Ltd..

Composition

Each tablet contains two active ingredients:

• Vildagliptin: 100 mg
• Dapagliflozin: 10 mg

Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that increases incretin hormones, stimulating insulin production and reducing liver glucose output, especially after meals. Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor, which helps the kidneys remove excess glucose from the body through urine, and may also promote weight loss and reduce blood pressure.

Uses

VILDAMAC DP 100 MG/10 MG TABLET is used for the following:

• Treatment of type 2 diabetes mellitus in adults, particularly when blood sugar is poorly controlled with metformin monotherapy, alongside a healthy diet and regular exercise.
• Lowering blood sugar levels and improving insulin sensitivity.
• Reducing the risk of cardiovascular death and hospitalization due to heart failure.
• Assisting in the treatment of chronic kidney disease associated with type 2 diabetes.

Dosage and Administration

This medicine is typically taken once or twice daily, as prescribed by your doctor. It should be taken consistently at the same time(s) each day to maintain a stable medication level in the body. VILDAMAC DP can be taken with or without food; however, taking it with food may help if stomach upset occurs. Swallow the tablet whole with a glass of water, and do not crush, chew, or break it. Do not stop taking the medication without consulting your doctor, as this could lead to increased blood sugar levels and serious complications.

Side Effects

Common side effects include:

• Nausea, vomiting, diarrhea, abdominal pain, loss of appetite.
• Headache, dizziness, tremor, fatigue, weakness.
• Hypoglycemia (low blood sugar), especially when taken with other diabetes medications.
• Urinary tract infections (UTIs), genital infections (e.g., thrush, vulvovaginitis, balanitis).
• Increased urination.
• Back pain, joint pain.
• Skin rash, itching.

Serious side effects can include symptoms of dehydration, severe allergic reactions, and lactic acidosis (characterized by symptoms like vomiting, stomach pain, muscle cramps, difficulty breathing, and low body temperature). Seek immediate medical attention if severe side effects occur.

Precautions

• Pregnancy and Breastfeeding: Caution is advised. Consult your doctor before use if you are pregnant or breastfeeding, as there are no well-controlled human studies.
• Kidney and Liver Issues: Inform your doctor if you have kidney or liver problems, as dosage adjustments or alternative medications may be necessary.
• Alcohol Consumption: Avoid excessive alcohol intake, as it may increase the risk of hypoglycemia and lactic acidosis.
• Driving and Operating Machinery: This medicine may cause dizziness, so exercise caution when driving or operating machines.
• Drug Interactions: Inform your doctor about all medicines, supplements, or herbal products you are taking. Interactions can occur with other blood sugar-lowering medicines (e.g., glimepiride, insulin), diuretics (e.g., furosemide), medicines that reduce inflammation (e.g., corticosteroids), thyroid medicines (e.g., levothyroxine), mood stabilizers (e.g., lithium), and iodinated contrast agents used in X-rays.
• Other Conditions: Inform your doctor if you have heart disease, low blood pressure, or a history of urinary tract or foot infections.
• Not recommended for children.

Storage

Store in a cool and dry place, away from sunlight. The medicine should be kept at room temperature, ideally below 30°C, and protected from moisture and heat. Keep out of sight and reach of children.

What is VILDAMAC DP 100 MG/10 MG TABLET used for?

VILDAMAC DP 100 MG/10 MG TABLET is a combination medicine used to manage blood sugar levels in adults with type 2 diabetes mellitus. It is typically prescribed when diet and exercise alone, or metformin monotherapy, do not adequately control blood sugar. This medication also helps reduce the risk of cardiovascular death and hospitalization due to heart failure, and assists in treating chronic kidney disease associated with type 2 diabetes.

How does VILDAMAC DP 100 MG/10 MG TABLET work?

VILDAMAC DP 100 MG/10 MG TABLET contains two active ingredients: Vildagliptin and Dapagliflozin.

• Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by increasing the levels of incretin hormones in the body, which stimulate the pancreas to produce more insulin after meals and reduce the amount of glucose produced by the liver.
• Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor. It works by preventing the kidneys from reabsorbing glucose back into the bloodstream, causing excess glucose to be eliminated from the body through urine. This also helps lower blood sugar and can promote weight loss and reduce blood pressure. The dual action of these two components helps achieve better overall blood sugar control by targeting different pathways involved in glucose regulation.

What is the usual dosage for VILDAMAC DP 100 MG/10 MG TABLET?

VILDAMAC DP 100 MG/10 MG TABLET should be taken exactly as prescribed by your doctor. The usual dosage is typically once or twice daily, depending on individual needs and response to treatment. It is recommended to take the medicine at the same time each day, with or without food, to maintain consistent blood sugar levels. Do not crush, chew, or break the tablet, and do not exceed the prescribed dose.

What are the possible side effects of VILDAMAC DP 100 MG/10 MG TABLET?

Common side effects may include:

• Hypoglycemia (low blood sugar), especially when taken with other diabetes medications.
• Urinary tract infections (UTIs) and genital infections (e.g., vaginal inflammation, balanitis), which are typically mild to moderate.
• Nausea, vomiting, diarrhea, or abdominal pain.
• Headache, dizziness, or tremor.
• Increased urination.
• Back pain and joint pain.
• Rash or itching.

If you experience any severe side effects, such as symptoms of dehydration, severe dizziness, or allergic reactions, seek immediate medical attention.

Is VILDAMAC DP 100 MG/10 MG TABLET safe during pregnancy or breastfeeding?

There is limited information regarding the use of Dapagliflozin and Vildagliptin (the components of VILDAMAC DP) during pregnancy. It is recommended to consult your doctor if you are pregnant or planning a pregnancy, as they may prescribe this medicine only if the benefits outweigh the risks.

VILDAMAC DP 100 MG/10 MG TABLET is generally not recommended during breastfeeding, as it is unknown whether the medicines are excreted in breast milk. It is important to inform your doctor if you are breastfeeding.

Can VILDAMAC DP 100 MG/10 MG TABLET be taken with other medications?

It is crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking or might take, to avoid potential interactions.

• Other blood sugar-lowering medicines (e.g., insulin, sulfonylureas like glimepiride, glipizide): Concurrent use may increase the risk of hypoglycemia (low blood sugar), and dose adjustments may be needed.
• Diuretics (water pills, e.g., furosemide, hydrochlorothiazide): May increase the risk of dehydration and low blood pressure due to the effects of dapagliflozin.
• Corticosteroids (e.g., prednisolone, hydrocortisone): Can reduce the effect of VILDAMAC DP.
• Thyroid medicines (e.g., levothyroxine): May interact.
• Anticonvulsants (e.g., phenytoin, phenobarbital): May interact.
• Alcohol: Avoid excessive alcohol consumption as it can increase the risk of hypoglycemia and lactic acidosis.

What precautions should be taken with VILDAMAC DP 100 MG/10 MG TABLET?

• Kidney and Liver Issues: Inform your doctor if you have any pre-existing kidney or liver disease, as dosage adjustments or alternative medications may be necessary.
• Dehydration: Drink plenty of fluids to prevent dehydration, especially as dapagliflozin can increase urination.
• Infections: Maintain good hygiene to reduce the risk of urinary tract and genital fungal infections.
• Driving and Operating Machinery: This medicine may cause dizziness, so drive or operate machines only if you are alert.
• Alcohol Consumption: Avoid alcohol while taking this medicine.
• Not for Children: VILDAMAC DP is not recommended for children as its safety and effectiveness have not been established.
• Regular Monitoring: Regular monitoring of blood sugar levels, and possibly kidney function, is essential while on this medication.

What happens if a dose of VILDAMAC DP 100 MG/10 MG TABLET is missed?

If you miss a dose of VILDAMAC DP 100 MG/10 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should VILDAMAC DP 100 MG/10 MG TABLET be stored?

Store VILDAMAC DP 100 MG/10 MG TABLET in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children. It does not require refrigeration.