Neugatrip Tab

NEUGATRIP TAB is a medicine manufactured by SUN PHARMACEUTICAL INDUSTRIES LTD.

Name

Brand Name: NEUGATRIP TAB

Composition

NEUGATRIP TAB is a combination medicine containing:

• Amitriptyline: 10 mg
• Pregabalin: 75 mg

Uses

NEUGATRIP TAB is primarily used to manage neuropathic pain, which is pain caused by nerve damage. This includes conditions such as:

• Peripheral neuropathies (nerve pain in hands and legs)
• Diabetic neuropathy (nerve pain due to diabetes)
• Trigeminal neuralgia (pain in the face)
• Post-herpetic neuralgia (pain after shingles)
• Chronic lower back pain and spondylitis
• Neuritis (nerve inflammation) and radiculopathy (nerve root damage)
• Fibromyalgia and spinal cord injury-related pain

Dosage and Administration

This medicine should be taken orally with or without food, as advised by your doctor. It is recommended to take it at a fixed time each day to maintain consistent blood levels. Do not chew, crush, or break the tablet. Do not stop taking NEUGATRIP TAB suddenly, as it may cause withdrawal symptoms; the dosage should be gradually tapered under medical supervision.

Side Effects

Common side effects may include:

• Dizziness, drowsiness, headache
• Nausea, vomiting, dry mouth, bloating
• Weight gain, blurred vision, tiredness
• Increased hunger or thirst
• Decreased sexual interest, difficulty in erection, delayed ejaculation
• Difficulty in concentration, memory impairment, speech difficulties
• Swelling of the body (edema)

Serious side effects, though rare, can include severe allergic reactions (rash, swelling), suicidal thoughts, severe constipation, jaundice, and abnormal heart rate.

Precautions

Inform your doctor if you are pregnant or breastfeeding, as NEUGATRIP TAB is generally not recommended in these situations. Use with caution in elderly patients and children. Avoid alcohol consumption as it can enhance side effects like dizziness and sleepiness. Caution is advised for patients with kidney or liver impairment, heart disease, glaucoma, bipolar syndrome, or a history of suicidal thoughts. Do not drive or operate heavy machinery if you experience dizziness or drowsiness.

Storage

Store NEUGATRIP TAB in a cool, dry place, away from direct sunlight and moisture, preferably below 30°C. Keep it in its original packaging and out of reach of children and pets.

NEUGATRIP TAB is a medication containing a combination of Pregabalin and Amitriptyline, primarily used for the management of neuropathic pain. Here are some frequently asked questions about Neugatrip Tablet:

What is Neugatrip Tablet used for?

Neugatrip Tablet is primarily used to manage neuropathic pain, which is nerve-related pain caused by damage to nerves or a malfunctioning nervous system. This includes conditions such as diabetic peripheral neuropathy (nerve pain due to diabetes), post-herpetic neuralgia (nerve pain after shingles), spinal cord injury-related pain, and fibromyalgia. It can help alleviate symptoms like burning, shooting, tingling, or stabbing pain.

How does Neugatrip Tablet work?

Neugatrip Tablet combines two active ingredients: Pregabalin and Amitriptyline. Pregabalin, an anti-convulsant, works by binding to specific sites on voltage-gated calcium channels in the central nervous system, which helps reduce the release of neurotransmitters that transmit pain signals. Amitriptyline, a tricyclic antidepressant, increases the levels of chemical messengers like serotonin and noradrenaline in the brain, thereby decreasing the movement of pain receptors. Together, they help to calm overactive nerves and relieve neuropathic pain.

What is the usual dosage for Neugatrip Tablet?

The specific dosage of Neugatrip Tablet will be determined by your doctor based on your medical condition and response to treatment. It typically contains Amitriptyline 10mg and Pregabalin 75mg. It is important to take this medicine exactly as prescribed by your doctor, at a fixed time each day to maintain consistent levels in your body. Do not exceed the prescribed dose.

What are the possible side effects of Neugatrip Tablet?

Common side effects can include weight gain, dry mouth, blurred vision, dizziness, tiredness, drowsiness, nausea, vomiting, diarrhea, constipation, headache, and increased heart rate. More serious, but rare, side effects can include severe blurred vision, unusual mood changes, increased heartbeat, and suicidal thoughts. If any side effects persist or worsen, you should consult your doctor.

Is Neugatrip Tablet safe during pregnancy or breastfeeding?

Neugatrip Tablet is generally not recommended for use during pregnancy, and its use during breastfeeding is considered potentially unsafe, as the drug may pass into breast milk. Limited human studies exist, and animal studies have shown potential harmful effects on the developing baby. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding, to weigh the benefits against potential risks.

Can Neugatrip Tablet be taken with other medications?

It is crucial to inform your doctor about all medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins, as Neugatrip Tablet can interact with various substances. It is contraindicated with Monoamine Oxidase Inhibitors (MAOIs) and should not be used if you have taken MAOIs within the last 14 days. Other interactions can occur with medications like cisapride, methylene blue, certain antidepressants, and benazepril.

What precautions should be taken while using Neugatrip Tablet?

Avoid consuming alcohol while taking Neugatrip Tablet, as it can increase drowsiness and dizziness. Due to potential drowsiness, dizziness, or blurred vision, you should not drive or operate heavy machinery until you know how the medication affects you. Use with caution if you have heart problems, liver or kidney impairment, bipolar disorder, glaucoma, or an overactive thyroid. This medication should not be given to children as its safety and effectiveness have not been established. There is also a risk of suicidal thoughts, so consult your doctor immediately if you or anyone else experiences such thoughts.

What happens if a dose of Neugatrip Tablet is missed?

If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects.

How should Neugatrip Tablet be stored?

Neugatrip Tablet should be stored in a cool, dry place, away from direct sunlight and moisture. Keep it in its original packet or container, tightly closed, and out of sight and reach of children. It is generally recommended to store it at temperatures between 10°C to 30°C or below 30°C.

Can I stop taking Neugatrip Tablet when my pain is relieved?

No, you should not stop taking Neugatrip Tablet suddenly, even if your pain has improved. Abruptly discontinuing the medication can lead to withdrawal symptoms such as anxiety, difficulty sleeping, nausea, increased pain, and sweating. Your doctor will advise you on how to gradually reduce the dose before stopping the medication completely.