Verifica Dm Tab

VERIFICA DM TAB

Name: VERIFICA DM (Brand Name), VERIFICA DM Tablet (Common Name) Manufacturer: Lupin Ltd.

Composition: VERIFICA DM Tablet is a combination medication containing three active pharmaceutical ingredients:

• Dapagliflozin: 10 mg
• Metformin: 500 mg
• Vildagliptin: 100 mg

Uses: VERIFICA DM Tablet is primarily used for the treatment of Type 2 Diabetes Mellitus in adults. It helps control high blood sugar levels when diet and exercise alone are insufficient. Its mechanisms include improving insulin sensitivity, reducing glucose production in the liver, increasing insulin release, and promoting the excretion of excess glucose through urine. It may also offer cardiovascular and renal protection and assist in weight management for some patients.

Dosage and Administration: Typically, VERIFICA DM Tablet is taken once or twice daily, preferably with meals to minimize gastrointestinal discomfort. The tablets should be swallowed whole with water and not crushed, chewed, or broken. Dosage should be strictly adhered to as prescribed by a healthcare professional, based on individual patient needs, blood sugar levels, and kidney function. Regular monitoring of blood sugar is essential.

Side Effects:

• Common: Low blood sugar (hypoglycemia, with symptoms like shaking, fast heartbeat, confusion, sweating), belly pain, upset stomach, vomiting, diarrhea, loss of appetite, metallic taste, headache, dizziness, fatigue, nausea, painful urination, repetitive urination, vaginal yeast infection, nasopharyngitis, inflammation of the penis (in men), and allergic reactions.
• Serious (Less Common): Lactic acidosis (symptoms include rapid breathing, abdominal pain, muscle cramps), liver problems (yellowing of skin/eyes, dark urine), very low or very high blood sugar, trouble breathing, and severe allergic reactions (wheezing, chest tightness, swelling of face/lips/tongue/throat).

Precautions: VERIFICA DM Tablet is not recommended for Type 1 diabetes, diabetic ketoacidosis, acute or chronic metabolic acidosis, or severe dehydration. It should be used with caution in patients with kidney or liver disease, heart problems, or urinary tract infections. Inform your doctor if you are pregnant or breastfeeding, as it is generally not recommended during these periods. Alcohol consumption should be avoided as it can increase the risk of hypoglycemia and lactic acidosis. Inform your doctor about all other medications you are taking, as drug interactions can occur with beta-blockers, diuretics, and certain heart medications. This medicine is not recommended for children below 18 years of age.

Storage: Store VERIFICA DM Tablet in a cool, dry place, protected from moisture and light, at a temperature below 25°C or 30°C. Keep out of the reach of children. Do not use past the expiry date.

VERIFICA DM TAB, manufactured by Lupin Ltd., is a combination medication primarily used for the management of Type 2 Diabetes Mellitus. It combines three active ingredients: Dapagliflozin, Metformin, and Vildagliptin, which work together to help control blood sugar levels.

Here are some frequently asked questions about VERIFICA DM TAB:

What is VERIFICA DM TAB used for?

VERIFICA DM TAB is used to treat Type 2 Diabetes Mellitus (T2DM) in adults. It works as an adjunct to diet and exercise to improve glycemic control. It helps lower high blood sugar levels, improve insulin sensitivity, and in some cases, manage insulin resistance associated with Polycystic Ovary Syndrome (PCOS), reduce the risk of heart disease, and aid in weight management.

How does VERIFICA DM TAB work?

This medication contains a combination of Dapagliflozin, Metformin, and Vildagliptin. Dapagliflozin (a sodium-glucose cotransporter-2 inhibitor) increases the excretion of glucose through urine, lowering blood sugar levels. Metformin (a biguanide) reduces glucose production in the liver, decreases sugar absorption from the intestines, and enhances the body's response to insulin. Vildagliptin (a dipeptidyl peptidase-4 inhibitor) increases the levels of incretin hormones, which stimulate the pancreas to release more insulin when blood sugar is high and signal the liver to stop producing sugar.

What is the usual dosage for VERIFICA DM TAB?

The recommended dosage of VERIFICA DM TAB varies based on individual patient needs, response to treatment, blood sugar levels, kidney function, and other medications being taken. It is usually taken once or twice daily, preferably with meals to minimize gastrointestinal discomfort. The tablet should be swallowed whole with water and not crushed or chewed. Always follow your doctor's instructions regarding dosage and duration.

What are the possible side effects of VERIFICA DM TAB?

Common side effects include low blood sugar levels (hypoglycemia), painful and repetitive urination, inflammation of the penis (in men), allergic reactions, nausea, vomiting, diarrhea, stomach pain, loss of appetite, metallic taste, headache, dizziness, fatigue, and skin rash. Less common but potentially serious side effects include lactic acidosis, which requires immediate medical attention if symptoms like rapid breathing, abdominal pain, or muscle cramps occur.

Is VERIFICA DM TAB safe during pregnancy or breastfeeding?

VERIFICA DM TAB is generally not recommended for use during pregnancy or breastfeeding. Limited information is available regarding its use in pregnant women, and it may pass into breast milk. It is crucial to consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking this medication.

Can VERIFICA DM TAB be taken with other medications?

Yes, but caution is advised as VERIFICA DM TAB can interact with several other medications. Inform your doctor about all current medications, supplements, or herbal products you are taking. Interactions can occur with diuretics, certain heart medicines (e.g., beta-blockers, ACE inhibitors), cimetidine, birth control pills, cationic medications (e.g., amiloride, digoxin), and iodinated contrast agents used in X-rays or scans. If you are taking insulin or sulfonylureas, your doctor may need to adjust their dosage.

What precautions should be taken while using VERIFICA DM TAB?

VERIFICA DM TAB is not suitable for individuals with Type 1 diabetes, diabetic ketoacidosis, severe dehydration, or acute/chronic metabolic acidosis. It should be used with caution or avoided in patients with kidney or liver problems, heart disease, or severe infections. Alcohol consumption should be limited or avoided as it can increase the risk of low blood sugar and lactic acidosis. It is not recommended for children under 18 years of age. Inform your doctor if you are scheduled for surgery or imaging procedures.

What happens if a dose of VERIFICA DM TAB is missed?

If you miss a dose of VERIFICA DM TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should VERIFICA DM TAB be stored?

VERIFICA DM TAB should be stored at room temperature, typically below 25°C or 30°C, in a cool, dry place. Keep it out of the reach of children and protect it from moisture and light. Do not use the medication past its expiry date.