Cospiaq M 12.5/1000mg Tab

COSPIAQ M 12.5/1000MG TABLET

COSPIAQ M 12.5/1000MG Tablet, manufactured by Torrent Pharmaceuticals Ltd, is a combination medication used in the management of Type 2 diabetes mellitus. It is often referred to as COSPIAQ MET 12.5/1000 TABLET.

• Composition Each tablet contains:

  • Empagliflozin: 12.5 mg
  • Metformin: 1000 mg

• Uses COSPIAQ M 12.5/1000MG Tablet is prescribed for adults to manage Type 2 diabetes mellitus, alongside diet and exercise. It is particularly indicated for those whose blood sugar is not adequately controlled by metformin alone or in combination with other antidiabetic medicines. This medication helps in controlling high blood glucose levels by aiding the removal of excess glucose through urine and improving insulin sensitivity. It also helps reduce the risk of cardiovascular death and hospitalization for heart failure in diabetic patients.

• Dosage and Administration This medicine should be taken orally as directed by a physician. It can be taken with or without food, but taking it at the same time each day is recommended for optimal benefits. Tablets should be swallowed whole and not crushed, broken, or chewed. The dose and duration are determined by the doctor based on the patient's age, body weight, and disease condition.

• Side Effects Common side effects may include:

  • Hypoglycemia (low blood glucose), especially when used with other antidiabetic medicines or alcohol.
  • Urinary tract infections (UTIs) and genital fungal infections.
  • Gastrointestinal issues like nausea, vomiting, diarrhea, stomach pain, and loss of appetite.
  • Dehydration, excessive thirst, and a change in taste.

  Serious side effects, though rare, can include lactic acidosis (symptoms like vomiting, stomach pain, muscle cramps, difficulty breathing) and severe allergic reactions.

• Precautions COSPIAQ M 12.5/1000MG Tablet is generally not recommended for Type 1 diabetes, or in pregnant or breastfeeding women due to lack of safety data. Caution is advised in elderly patients (above 65 years) and those with kidney or liver disorders. Alcohol consumption should be avoided as it increases the risk of lactic acidosis. Patients should inform their doctor about any allergies or if they are taking diuretics, insulin, sulfonylureas, or NSAIDs, as interactions can occur.

• Storage Store in a cool and dry place, away from direct sunlight and out of reach of children.

COSPIAQ M 12.5/1000MG TAB is a medication containing Empagliflozin (12.5mg) and Metformin (1000mg). It is used to manage Type 2 diabetes mellitus in adults. Below are frequently asked questions about this medication.

1. What is COSPIAQ M 12.5/1000MG TAB used for?

COSPIAQ M 12.5/1000MG TAB is primarily used alongside diet and exercise to treat high blood sugar levels in adults with Type 2 diabetes mellitus. It is prescribed when blood sugar is not adequately controlled by metformin alone or with other antidiabetic medications. Additionally, it helps lower the risk of cardiovascular death in patients with Type 2 diabetes and established cardiovascular disease, and can reduce the risk of worsening kidney disease, end-stage kidney disease, and hospitalization in patients with chronic kidney disease.

2. How does COSPIAQ M 12.5/1000MG TAB work?

This medication combines two active ingredients: Empagliflozin and Metformin.

• Empagliflozin is a Sodium-Glucose Co-transporter-2 (SGLT2) inhibitor. It works in the kidneys to prevent the reabsorption of glucose (blood sugar), leading to increased glucose excretion through urine and thus lowering blood sugar levels.
• Metformin is a biguanide that reduces the production of glucose in the liver, decreases the absorption of glucose from the intestines, and improves the body's sensitivity to insulin, allowing it to use sugar more effectively.

3. What is the usual dosage for COSPIAQ M 12.5/1000MG TAB?

The typical dosage is one tablet taken twice a day with food. Your doctor may adjust the dose as needed and tolerated, but the total daily dose is usually not more than 25 mg of empagliflozin and 2000 mg of metformin. Taking it with food can help minimize gastrointestinal side effects.

4. What are the possible side effects of COSPIAQ M 12.5/1000MG TAB?

Common side effects may include low blood sugar (hypoglycemia), urinary tract infections (UTIs), genital yeast infections (in both men and women), increased urination, nausea, vomiting, diarrhea, stomach pain, loss of appetite, metallic taste in the mouth, headache, and fatigue.

Serious but less common side effects can include lactic acidosis (symptoms like severe stomach discomfort, muscle pain, trouble breathing, unusual tiredness, feeling cold, dizziness, or irregular heartbeat), severe allergic reactions, dehydration, diabetic ketoacidosis, and a rare but serious infection around the genitals (Fournier's gangrene). There is also a potential increased risk of lower limb amputations.

5. Is COSPIAQ M 12.5/1000MG TAB safe during pregnancy or breastfeeding?

Pregnancy: This medication is generally not recommended during pregnancy. It is considered unsafe during the second and third trimesters as it could harm an unborn baby. If you are pregnant or planning to become pregnant, discuss this with your doctor to review your treatment. Breastfeeding: COSPIAQ M 12.5/1000MG TAB is generally not recommended while breastfeeding. While it's unlikely to pass into breast milk in clinically significant amounts, the manufacturer advises against its use due to a theoretical risk to the infant's developing kidneys.

6. Can COSPIAQ M 12.5/1000MG TAB be taken with other medications?

Interactions with other medications are possible. It is crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking or plan to take.

• Taking it with insulin or sulfonylureas (other diabetes medications like glipizide or glyburide) can increase the risk of low blood sugar, and dose adjustments may be necessary.
• Diuretics (water pills) can increase the risk of dehydration.
• Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen may affect kidney function, potentially increasing metformin side effects.
• It is generally advised to avoid or minimize alcohol consumption, as it can significantly increase the risk of lactic acidosis.

7. What precautions should be taken while using COSPIAQ M 12.5/1000MG TAB?

Do not use this medication if you have Type 1 diabetes, severe kidney or liver disease, uncontrolled diabetes, severe infections, or certain heart conditions like recent heart attack or heart failure.

• Your doctor will regularly monitor your kidney function, especially if you are elderly.
• If you experience conditions leading to dehydration (e.g., severe vomiting, diarrhea, fever, or reduced fluid intake), temporary discontinuation of the medication may be necessary.
• Diabetic individuals should pay close attention to foot care due to the potential risk of lower limb complications.
• Maintain good genital hygiene to help prevent yeast or urinary tract infections.
• Do not stop taking this medication abruptly, as it can cause blood sugar levels to rise and increase the risk of serious complications.

8. What happens if a dose of COSPIAQ M 12.5/1000MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

9. How should COSPIAQ M 12.5/1000MG TAB be stored?

Store this medicine in a cool, dry place, and keep it out of reach of children.