Zinodap 10

Name:

• Brand Name: ZINODAP 10mg Tablet
• Manufacturer: Wockhardt Ltd.

Composition:

• Active Ingredient: Dapagliflozin (10mg)
• Chemical Class: Phenolic Glycosides Derivative; Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitor

Uses: ZINODAP 10mg Tablet is primarily prescribed for the management of Type 2 Diabetes Mellitus to lower blood glucose levels. It helps the body remove excess sugar through urine. Additionally, it is used in adults for:

• Management of heart failure.
• Treatment of chronic kidney disease (reduced kidney function). It can also help reduce the risk of heart-related complications in patients with type 2 diabetes.

Dosage and Administration: ZINODAP 10mg Tablet should be taken orally once a day, with or without food. It is advised to take it at the same time each day for optimal results. The dosage is determined by a doctor, but a typical starting dose for adults might be 5 mg, which can be increased to 10 mg once daily, not exceeding 10 mg per day. Do not stop taking the medicine without consulting a doctor. It is not recommended for children and adolescents under 18 years.

Side Effects: Common side effects include:

• Fungal infections (vaginal/genital)
• Urinary tract infections (UTIs)
• Increased urination (polyuria)
• Nausea
• Nasopharyngitis (inflammation of the throat and nasal passages)
• Back pain
• Dizziness
• Rash
• Constipation, dry mouth, dehydration Serious side effects, though less common, can include diabetic ketoacidosis and severe allergic reactions.

Precautions:

• Avoid if allergic to dapagliflozin or any of its components.
• Caution is advised in patients with kidney or liver problems.
• Inform your doctor if you have type 1 diabetes, severe low blood pressure, severe dehydration, or conditions causing dehydration (e.g., nausea, vomiting, fever).
• Consumption of alcohol is unsafe as it can affect blood sugar levels.
• Consult a doctor regarding use during pregnancy and breastfeeding, as it is generally not recommended.
• Monitor blood sugar levels and kidney function regularly.
• Drink plenty of fluids to prevent dehydration.

Storage: Store ZINODAP 10mg Tablet below 30°C. Keep it in a cool, dry place, protected from direct sunlight and moisture, and out of reach of children.

ZINODAP 10 by WOCKHARDT LTD is a medication primarily used for managing Type 2 Diabetes Mellitus. It contains Dapagliflozin as its active ingredient, which belongs to a class of drugs called sodium-glucose cotransporter 2 (SGLT2) inhibitors.

What is ZINODAP 10 used for?

ZINODAP 10 is mainly prescribed for adults to manage type 2 diabetes mellitus, often alongside a balanced diet and regular exercise. It helps to lower high blood sugar levels. Additionally, it is used to treat heart failure in adults where the heart struggles to pump blood effectively, and to manage chronic kidney disease in adults with reduced kidney function, helping to protect the kidneys from further damage.

How does ZINODAP 10 work?

ZINODAP 10 works by blocking the action of a protein called SGLT2 in the kidneys. This action prevents the reabsorption of glucose back into the bloodstream, leading to the excretion of excess sugar from the body through urine. This process effectively lowers blood sugar levels. It also reduces the strain on the heart, helping it pump blood more efficiently, and protects kidney function.

What is the usual dosage of ZINODAP 10?

For adults, the typical starting dose is 5 mg taken orally once a day, with or without food. Depending on the individual's response, the dose may be increased to 10 mg once daily, but it should not exceed 10 mg per day. It is generally advised to take the tablet at the same time each day for optimal results and consistent blood sugar levels. ZINODAP 10 is not recommended for children and adolescents under 18 years of age.

What are the possible side effects of ZINODAP 10?

Common side effects associated with ZINODAP 10 include vaginal yeast infections, urinary tract infections (UTIs), nasopharyngitis (inflammation of the nasal passages and throat), increased urination, dehydration, nausea, vomiting, dizziness, rash, back pain, constipation, and increased thirst. Most of these side effects are temporary and resolve as your body adapts to the medication.

Is ZINODAP 10 safe during pregnancy or breastfeeding?

ZINODAP 10 is generally not recommended during pregnancy, especially during the second and third trimesters, due to potential risks to the fetus. Similarly, it is not recommended during breastfeeding as it is unknown if the medication or its components pass into human milk and could potentially harm the baby. It is crucial to consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Can ZINODAP 10 be taken with other medications?

ZINODAP 10 can interact with certain medications. For example, taking it with diuretics (water pills) like furosemide or hydrochlorothiazide can increase the risk of dehydration. When taken with other antidiabetic drugs such as insulin or sulfonylureas (e.g., glimepiride), there is an increased risk of low blood sugar (hypoglycemia). It's essential to inform your doctor about all medications, supplements, or herbals you are currently taking to avoid potential interactions.

What precautions should be taken while using ZINODAP 10?

Before starting ZINODAP 10, inform your doctor if you have kidney or liver problems, urinary tract infections, severe low blood pressure, or conditions that can lead to dehydration (like severe vomiting or diarrhea). Staying well-hydrated is important to prevent dehydration. Practicing good personal hygiene can help prevent genital fungal and urinary tract infections. Avoid consuming alcohol as it can lead to high or low blood sugar levels. Regularly monitor your blood sugar levels as advised by your healthcare provider.

What happens if a dose of ZINODAP 10 is missed?

If you miss a dose of ZINODAP 10, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should ZINODAP 10 be stored?

ZINODAP 10 should be stored in a cool, dry place, protected from direct sunlight and moisture. It is important to keep it out of the sight and reach of children. Store it below 30°C.