Mycept-s 180 Tabs

MYCEPT-S 180 TABS

Name

• Brand Name: MYCEPT-S 180 TABS
• Common Name: Mycophenolate Sodium (equivalent to Mycophenolic Acid)

Composition

Each delayed-release tablet contains Mycophenolate Sodium USP equivalent to 180 mg of Mycophenolic Acid.

Uses

MYCEPT-S 180 TABS is an immunosuppressant primarily used to prevent organ rejection in adult patients who have received an allogeneic kidney, heart, or liver transplant. It works by weakening the body's immune system to stop it from attacking the transplanted organ, often prescribed in combination with other immunosuppressive agents like ciclosporin and corticosteroids.

Dosage and Administration

Treatment should be initiated and maintained by qualified transplant specialists. The recommended dose for renal transplant recipients is typically 720 mg twice daily. MYCEPT-S 180 TABS should be taken orally on an empty stomach, either one hour before or two hours after meals. Tablets must be swallowed whole and should not be crushed, chewed, or broken. Consistent administration at the same times each day is advised.

Side Effects

• Common: Stomach pain, nausea, vomiting, diarrhea, headache, high blood pressure, swelling of lower legs/feet/ankles, leukopenia (low white blood cell count), anemia, dizziness, fatigue, and joint pain.
• Serious: Increased risk of infections (bacterial, fungal, viral, protozoal), lymphomas, other malignancies (especially skin cancer), and gastrointestinal tract ulceration, hemorrhage, or perforation.

Precautions

• Pregnancy and Breastfeeding: MYCEPT-S is contraindicated during pregnancy due to a significant risk of birth defects and miscarriage. Women of childbearing potential must use two reliable forms of contraception before, during, and for six weeks after treatment. It is also contraindicated in breastfeeding women as it passes into breast milk.
• Allergies: Do not use if allergic to mycophenolate sodium, mycophenolic acid, mycophenolate mofetil, or any other ingredients.
• Medical Conditions: Exercise caution in patients with active serious digestive system diseases, severe renal impairment, or rare genetic disorders like Lesch-Nyhan and Kelley-Seegmiller syndrome.
• Immunosuppression: Increased susceptibility to infections; avoid contact with individuals having infections such as chickenpox or shingles. There's an increased risk of skin cancer, so limit sun exposure, wear protective clothing, and use sunscreen.
• Vaccinations: Live vaccines should be avoided during therapy.
• Driving: May cause dizziness or confusion; operate machinery or drive only if alert.
• Drug Interactions: Inform your doctor about all medications, including antacids, lipid-lowering drugs, and antivirals, as interactions can occur.

Storage

Store MYCEPT-S 180 TABS in a cool, dry place below 30°C. Protect from direct sunlight and moisture. Keep out of the sight and reach of children.

MYCEPT-S 180 TABS, containing Mycophenolate sodium (Mycophenolic acid), is an immunosuppressant medication primarily used in transplant patients. Below are frequently asked questions about this medicine.

What is MYCEPT-S 180 TABS used for?

MYCEPT-S 180 TABS is used to prevent the body from rejecting a transplanted organ, such as a kidney, heart, or liver. It is typically used in combination with other medications like ciclosporin and corticosteroids.

How does MYCEPT-S 180 TABS work?

This medicine is an immunosuppressant that works by weakening the body's immune system. Its active ingredient, Mycophenolic acid, decreases the production of specific white blood cells (T and B lymphocytes) that would otherwise recognize and attack the transplanted organ as a foreign body, thereby preventing rejection.

What is the usual dosage for MYCEPT-S 180 TABS?

The recommended daily dose of Mycophenolic Acid is typically 720 mg administered twice daily, totaling 1,440 mg per day. The exact dosage, however, depends on the type of transplant and your doctor's instructions. It can be taken with or without food, but it is important to adhere to a consistent schedule (e.g., always with food or always without food). The tablets should be swallowed whole and not crushed, chewed, or broken.

What are the possible side effects of MYCEPT-S 180 TABS?

Common side effects can include nausea, vomiting, diarrhea, stomach pain, headache, high blood pressure, and a decreased white blood cell count (neutropenia). Due to its effect on the immune system, there is an increased risk of infections and, rarely, certain cancers like skin cancer and lymphoma. Other potential side effects include anxiety, dizziness, muscle pain, anemia, and changes in blood test results such as increased uric acid or creatinine levels.

Is MYCEPT-S 180 TABS safe during pregnancy or breastfeeding?

No, MYCEPT-S 180 TABS is considered unsafe during pregnancy as there is a definite risk of birth defects and miscarriage. Women of childbearing potential must use two highly effective forms of contraception before, during, and for at least six weeks after stopping treatment. A negative pregnancy test is required before starting this medication. It is also unsafe during breastfeeding because the medication can pass into breast milk and may harm the baby.

Can MYCEPT-S 180 TABS be taken with other medications?

MYCEPT-S 180 TABS is often used with other immunosuppressants like ciclosporin and corticosteroids. However, it can interact with other medicines, including certain antiviral drugs (e.g., aciclovir, ganciclovir), cholesterol-lowering agents (cholestyramine), some antibiotics (e.g., rifampicin), antacids, and proton pump inhibitors. It may also reduce the effectiveness of hormonal birth control, so additional reliable contraception methods are necessary. Live vaccines should be avoided while taking this medicine.

What precautions should be taken while on MYCEPT-S 180 TABS?

Patients taking MYCEPT-S 180 TABS are at an increased risk of infections and certain cancers, particularly skin cancer. It is crucial to limit exposure to sunlight and UV light by wearing protective clothing and using high-factor sunscreen. Any signs of infection (fever, sore throat), unexpected bruising, bleeding, or other symptoms of bone marrow depression should be reported to your doctor immediately. Regular blood tests are necessary to monitor blood cell counts and liver/kidney function. Males should also use effective contraception during treatment and for 90 days after discontinuation, and should not donate semen during this period.

What happens if a dose of MYCEPT-S 180 TABS is missed?

If you miss a dose of MYCEPT-S 180 TABS, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should MYCEPT-S 180 TABS be stored?

MYCEPT-S 180 TABS should be stored below 30°C in a cool, dry place, away from light and moisture. It is important to keep this medication out of the reach of children and pets. Do not store it in the bathroom.