Metafort G 853

Name:

• Brand Names: Metafort-G 853, Metafort G 853mg Tablet.
• Common Name: Glimepiride and Metformin.

Composition:

• Active Ingredients: Each tablet contains Glimepiride 3mg and Metformin 850mg.

Uses: Metafort-G 853 is an anti-diabetic medication used in the treatment of Type 2 Diabetes Mellitus in adults, particularly when blood sugar levels are not adequately controlled by diet, exercise, or a single antidiabetic agent.

• Management of Type 2 Diabetes: Helps lower blood sugar levels and improves glycemic control.
• Improvement of Insulin Sensitivity: Enhances the body's response to insulin and enables cells to use sugar more effectively.
• Reduction of Diabetes-Related Complications: Helps prevent complications such as kidney damage, eye problems, nerve issues, and cardiovascular risks.

Dosage and Administration:

• Metafort-G 853 should be taken as prescribed by your doctor, usually with meals.
• Swallow the tablet whole with a glass of water; do not chew, crush, or break it.
• For optimal benefits, take the medication consistently at the same time each day.
• The dosage is individualized by your healthcare provider based on your blood sugar levels and response to treatment.
• Do not stop taking this medicine without consulting your doctor, as discontinuing it can lead to elevated blood sugar levels and potential complications.

Side Effects:

• Common Side Effects: Stomach pain, nausea, diarrhea, vomiting, headache, metallic taste, dizziness, low blood sugar (hypoglycemia), taste disturbance, abdominal discomfort, upper respiratory tract infections, and weight gain.
• Serious Side Effects (Contact your doctor immediately if experienced):
  • Lactic acidosis (symptoms include vomiting, bellyache with muscle cramps, severe tiredness, reduced body temperature, low heartbeat, and difficulty in breathing).
  • Inflammation of the liver (may result in jaundice).
  • Severe allergic reactions (e.g., skin rash, hives, increased sensitivity to sun, inflammation of blood vessels, difficulty breathing, fall in blood pressure, shock).
  • Severe low blood sugar levels.

Precautions:

• Contraindications: Not recommended for individuals with Type 1 diabetes mellitus, diabetic ketoacidosis, diabetic coma, severe kidney or liver disease, metabolic acidosis, heart failure, severe infections, dehydration, shock, or known allergies to its components.
• Pregnancy and Breastfeeding: Generally not recommended during pregnancy or breastfeeding due to potential risks to the baby; consult a doctor for alternative treatment plans.
• Alcohol Consumption: Avoid alcohol as it increases the risk of lactic acidosis and low blood sugar levels.
• Driving and Operating Machinery: May decrease alertness, especially due to fluctuations in blood sugar. Exercise caution if experiencing dizziness or visual problems.
• Medical Conditions: Inform your doctor if you have kidney or liver problems, thyroid disorders, low vitamin B12 levels, or are scheduled for surgery or diagnostic tests involving iodine injections.
• Hypoglycemia Management: Be aware of symptoms of low blood sugar (sweating, trembling, dizziness, headache, hunger) and carry a quick source of glucose.
• Monitoring: Regular monitoring of blood sugar levels, blood counts, and liver function tests may be advised.

Storage:

• Store in a cool and dry place, away from direct sunlight.
• Keep out of reach of children and pets.
• Do not refrigerate or freeze.
• Keep the tablets in their original packaging until use.
• Ideal storage temperature is between 15°C to 30°C (59°F to 86°F).

Here are the most frequently asked questions about METAFORT G 853 by ERIS THERAPEUTICS LIMITED:

What is METAFORT G 853 used for?

METAFORT G 853 is an anti-diabetic drug primarily used to manage type 2 diabetes mellitus in adults. It is prescribed when blood sugar levels are not adequately controlled by diet and exercise alone. It helps lower blood sugar levels and can reduce the risk of diabetes-related complications such as kidney damage, eye problems, and nerve issues.

How does METAFORT G 853 work?

METAFORT G 853 contains a combination of two active ingredients: Glimepiride and Metformin. Glimepiride stimulates the pancreas to release more insulin, a hormone that helps lower blood sugar levels. Metformin works by decreasing the amount of sugar produced by the liver, slowing down sugar absorption from food in the intestines, and increasing the body's sensitivity to insulin, allowing cells to use insulin more effectively.

What is the usual dosage for METAFORT G 853?

This medication should be taken as prescribed by your doctor, usually with meals, to minimize gastrointestinal side effects. It is important to swallow the tablet whole with a glass of water and not to chew, crush, or break it. Your doctor will determine the appropriate dose, which may be adjusted based on your blood sugar response.

What are the possible side effects of METAFORT G 853?

Common side effects may include stomach pain, nausea, diarrhea, vomiting, headache, or a metallic taste. Low blood sugar (hypoglycemia) is also a common side effect, especially with alcohol intake, excessive exercise, or missed meals. Serious but rare side effects include lactic acidosis, an accumulation of lactic acid in the body, which can be life-threatening. Long-term use may also lead to Vitamin B12 deficiency.

Is METAFORT G 853 safe during pregnancy or breastfeeding?

METAFORT G 853 is generally not recommended during pregnancy as it may harm the unborn baby. Insulin is often preferred for controlling blood sugar levels in pregnant women with diabetes. It is also considered unsafe during breastfeeding as it may pass into breast milk and cause adverse effects in the baby.

Can METAFORT G 853 be taken with other medications?

Before taking METAFORT G 853, inform your doctor about all other medications, supplements, or herbal products you are currently taking. Some medicines, such as certain NSAIDs (e.g., ibuprofen, diclofenac), beta-blockers (e.g., propranolol), and ACE inhibitors (e.g., enalapril), can interact with METAFORT G 853, potentially affecting its efficacy or increasing the risk of side effects like hypoglycemia.

What precautions should be taken with METAFORT G 853?

Avoid alcohol consumption while taking METAFORT G 853 as it can increase the risk of low blood sugar and lactic acidosis. Do not take this medication if you have type 1 diabetes mellitus, diabetic ketoacidosis, or severe kidney or liver disease. Exercise caution if you have a history of heart disease. Regular monitoring of blood sugar levels and kidney function is advisable.

What happens if a dose of METAFORT G 853 is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing routine. Do not take a double dose to compensate for a missed one.

How should METAFORT G 853 be stored?

Store METAFORT G 853 in a cool, dry place, away from direct sunlight, ideally between 15°C to 30°C (59°F to 86°F). Keep it in its original packaging and out of reach of children and pets. Do not refrigerate or freeze the tablets.