Triolsar 12.5 Tab

TRIOLSAR 12.5 TAB, commonly known as Trilosar 12.5 Tablet, is a medication manufactured by Torrent Pharmaceuticals Ltd.. It is a combination medicine prescribed to manage hypertension (high blood pressure) when a single medication is not sufficiently effective.

• Name: Trilosar 12.5 Tablet (Brand Name) / TRIOLSAR 12.5 TAB
• Composition: Each tablet contains Losartan (50mg), Amlodipine (5mg), and Chlorthalidone (12.5mg).
  • Losartan is an angiotensin receptor blocker (ARB) that relaxes blood vessels.
  • Amlodipine is a calcium channel blocker (CCB) that widens and relaxes blood vessels.
  • Chlorthalidone is a diuretic (water pill) that removes excess water and certain electrolytes from the body through urine.
• Uses: Trilosar 12.5 Tablet is primarily used for:
  • Treating hypertension (high blood pressure).
  • Reducing the risk of future heart attacks and strokes.
  • Managing edema (swelling caused by fluid retention), especially associated with heart, liver, kidney, or lung diseases.
  • Protecting kidney function in patients with type 2 diabetes and hypertension.
  • Managing angina (chest pain).
• Dosage and Administration: This medicine should be taken as advised by a doctor. It is typically taken once daily, with or without food, preferably at the same time each day to maintain consistent blood levels. Do not chew, crush, or break the tablet. Due to its diuretic component, it is best to avoid taking this medicine within four hours of going to bed. It is crucial to continue taking the medication even if you feel well, as stopping abruptly can increase the risk of heart complications.
• Side Effects:
  • Common Side Effects: Headache, dizziness, tiredness, ankle swelling, taste change, nausea, upset stomach, increased urination, palpitations, sleepiness, increased blood uric acid, glucose intolerance, altered blood lipid levels.
  • Serious Side Effects (rare): Low blood pressure, kidney problems, electrolyte imbalances (e.g., low sodium, potassium, or magnesium), and allergic reactions. Seek immediate medical help if severe symptoms occur.
• Precautions:
  • Contraindicated in individuals with known allergies to any of its components, severe kidney or liver disease, low blood pressure (hypotension), cardiogenic shock, aortic stenosis, and anuria (inability to urinate).
  • Unsafe for use during pregnancy and generally avoided during breastfeeding, with consultation required for nursing mothers.
  • Alcohol consumption is unsafe as it can increase dizziness and the risk of low blood pressure.
  • Caution is advised in patients with diabetes (monitor blood sugar closely), gout (may increase uric acid levels), and heart failure.
  • May cause dizziness or blurred vision, which can affect the ability to drive or operate machinery.
• Storage: Store below 25°C or 30°C, away from moisture and heat. Keep it in its original container, tightly closed, and out of reach of children.

Here are the frequently asked questions (FAQs) about TRIOLSAR 12.5 TAB:

What is TRIOLSAR 12.5 TAB used for?

TRIOLSAR 12.5 TAB is primarily used to manage hypertension (high blood pressure) and reduce the risk of cardiovascular events such as stroke and heart attack. It can also be used in the treatment of heart failure, oedema (swelling due to fluid retention), and to protect kidney function in diabetic patients with kidney disease.

How does TRIOLSAR 12.5 TAB work?

TRIOLSAR 12.5 TAB is a combination medication containing three active ingredients: Olmesartan, Amlodipine, and Hydrochlorothiazide (or Chlorthalidone in some formulations, depending on the specific product name like Trilosar).

• Olmesartan (an angiotensin II receptor blocker - ARB) works by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict. This helps to relax and widen blood vessels, thereby lowering blood pressure.
• Amlodipine (a calcium channel blocker) prevents calcium from entering the muscle cells of the heart and blood vessels. This causes blood vessels to relax and widen, which lowers blood pressure and improves blood flow to the heart.
• Hydrochlorothiazide / Chlorthalidone (a thiazide diuretic or "water pill") helps the body get rid of excess salt and water through urine, which reduces blood volume and helps lower blood pressure. This combination provides a comprehensive approach to blood pressure control.

What is the usual dosage of TRIOLSAR 12.5 TAB?

Typically, the starting dose is one 12.5 mg tablet once daily. Your doctor may adjust the dosage based on your blood pressure response and how well you tolerate the medication. The tablet should be swallowed whole with a glass of water and can be taken with or without food, preferably at the same time each day to maintain consistent blood levels.

What are the possible side effects of TRIOLSAR 12.5 TAB?

Common side effects may include dizziness, lightheadedness, headache, fatigue, nausea, vomiting, diarrhea, cough, nasal congestion, sore throat, muscle cramps, increased potassium levels in the blood (hyperkalemia), and low blood pressure, especially when standing up (orthostatic hypotension). Other possible side effects include ankle swelling, sleepiness, changes in kidney function, increased blood uric acid levels, glucose intolerance, and altered blood lipid levels. If any side effects are severe or persistent, you should consult your healthcare provider.

Is TRIOLSAR 12.5 TAB safe during pregnancy or breastfeeding?

TRIOLSAR 12.5 TAB is generally not recommended during pregnancy, especially in the second and third trimesters, as it can harm the unborn baby. For breastfeeding mothers, the medication may pass into breast milk, and its effects on the baby are uncertain, so it's advised to consult your doctor.

Can TRIOLSAR 12.5 TAB be taken with other medications?

Yes, TRIOLSAR 12.5 TAB can interact with certain other medications. It's important to inform your doctor about all medications you are taking, including over-the-counter drugs, supplements, and herbal products. Potential interactions include diuretics (water pills), NSAIDs (nonsteroidal anti-inflammatory drugs like ibuprofen), lithium, certain antifungal medications, and other blood pressure medications.

What precautions should be taken while taking TRIOLSAR 12.5 TAB?

Before taking TRIOLSAR 12.5 TAB, inform your doctor if you have any allergies, severe kidney or liver problems, heart conditions (like low blood pressure, heart attack history, cardiogenic shock, or aortic stenosis), diabetes, or electrolyte imbalances. Regular monitoring of blood pressure, kidney function, and electrolyte levels is recommended. It may cause dizziness, so be cautious when standing up or performing activities that require alertness. It is important not to abruptly stop taking the medication without consulting your doctor, as this can lead to a sudden increase in blood pressure.

What happens if a dose of TRIOLSAR 12.5 TAB is missed?

If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose, as this can cause your blood pressure to drop too low and increase the risk of side effects like dizziness. If you are unsure, it's best to consult your doctor or pharmacist.

How should TRIOLSAR 12.5 TAB be stored?

TRIOLSAR 12.5 TAB should be stored in a cool and dry place, away from sunlight. Keep it out of the sight and reach of children and pets. Do not use the medicine past its expiry date.