Britzilam 75 Tablet

BRITZILAM 75 TABLET

Name: BRITZILAM 75 TABLET (Brand Name), Brivaracetam (Common Name)

Composition: BRITZILAM 75 TABLET contains Brivaracetam 75 mg as its active ingredient.

Uses: BRITZILAM 75 TABLET is an anti-epileptic medication primarily used to manage seizures associated with epilepsy. It is effective for treating partial-onset seizures in adults and children aged one month and older. It can be used as a monotherapy or as an adjunctive therapy with other antiepileptic drugs to help control and reduce the frequency of seizures. Brivaracetam works by attaching to specific sites (SV2A) on nerve cells, suppressing abnormal electrical activity in the brain and preventing the spread of signals that cause seizures.

Dosage and Administration:

• Adults: The usual starting dose is 50 mg twice daily, which may be adjusted by a healthcare professional based on individual response and tolerability, up to a maximum recommended dose of 200 mg twice daily.
• Children: The dosage for children is determined based on their body weight and is typically prescribed by a healthcare professional specializing in pediatric epilepsy treatment.
• Administration: Swallow the tablet whole with a glass of water, with or without food. Do not crush, chew, or break the tablet. It is recommended to take the medicine at the same time each day to maintain a consistent level in the body. Do not stop taking the medicine suddenly without consulting your doctor, as abrupt cessation can worsen seizures.

Side Effects:

• Common Side Effects: Feeling sleepy or dizzy, fatigue, nausea, vomiting, constipation, headache, flu-like symptoms, irritability, anxiety, mood changes, insomnia (not being able to sleep), infections of the nose and throat, cough, decreased appetite.
• Serious Side Effects: In rare cases, individuals may experience behavioral changes such as aggression, agitation, restlessness, hyperactivity, nervous excitement, or self-harming thoughts. Suicidal thoughts have also been reported. Contact your doctor if any symptoms worsen or if you experience concerning mood changes.

Precautions:

• Pregnancy and Breastfeeding: Not recommended for use in pregnant or breastfeeding women unless considered necessary and after consulting a doctor, as it may pass through breast milk.
• Liver and Kidney Impairment: Use with caution in patients with liver disease, as dose adjustment may be required. Caution is also advised for kidney issues.
• Alcohol: Avoid consuming alcohol as it can increase drowsiness, dizziness, and affect memory and attention.
• Driving and Operating Machinery: BRITZILAM 75 TABLET may cause drowsiness, dizziness, and affect alertness. Avoid driving or operating machinery until you know how the medicine affects you.
• Psychiatric Disorders: Inform your doctor if you have a history of depression, suicidal thoughts, or any unusual changes in mood and behavior, as the medicine may exacerbate existing neuropsychiatric conditions. Close monitoring may be required.
• Drug Interactions: Inform your doctor about all medicines, including other antiepileptic drugs (e.g., carbamazepine, phenytoin), antibiotics (e.g., rifampin), and CNS depressants (e.g., opioids, antidepressants, antianxiety medicines), as BRITZILAM 75 TABLET can interact with them.

Storage: Store below 30°C in a cool, dry place. Keep it in the original packaging to protect it from moisture and heat. Keep out of the reach of children and pets.

BRITZILAM 75 Tablet, containing Brivaracetam, is an anti-epileptic medication used to manage seizures in individuals with epilepsy. It works by stabilizing abnormal electrical activity in the brain.

What is BRITZILAM 75 Tablet used for?

BRITZILAM 75 Tablet is primarily used to manage partial-onset seizures in adults, adolescents, and children aged one month and older who have epilepsy. It can be used alone (monotherapy) or in combination with other anti-epileptic drugs (adjunctive therapy) to help control and reduce the frequency of seizures.

How does BRITZILAM 75 Tablet work?

BRITZILAM 75 Tablet contains Brivaracetam, which works by selectively binding to synaptic vesicle protein 2A (SV2A) in the brain. This action helps to regulate abnormal neuronal electrical activity, thereby calming overactive nerve cells and preventing the excessive spread of electrical signals that trigger epileptic seizures.

What is the usual dosage for BRITZILAM 75 Tablet?

The dosage of BRITZILAM 75 Tablet is determined by a doctor based on individual response, tolerability, age, and body weight, especially for children. For adults, the usual starting dose is often 50 mg twice daily, and it may be adjusted up to a maximum recommended dose of 200 mg twice daily. It should be taken regularly, preferably at the same time each day, with or without food, as advised by your doctor.

What are the possible side effects of BRITZILAM 75 Tablet?

Common side effects include drowsiness, dizziness, fatigue, nausea, vomiting, irritability, anxiety, and mood changes. Some individuals may also experience headaches, constipation, or flu-like symptoms. In rare cases, more serious side effects like behavioral changes (aggression, agitation) or thoughts of self-harm have been reported. It is important to contact your doctor if you experience any severe or persistent side effects.

Is BRITZILAM 75 Tablet safe during pregnancy or breastfeeding?

If you are pregnant, suspect you might be pregnant, or are planning to conceive, it is essential to consult your doctor before using BRITZILAM 75 Tablet. It may be unsafe to use during pregnancy, as animal studies have shown potential harm to the developing baby.

For breastfeeding mothers, BRITZILAM 75 Tablet should be used with caution, as information regarding its use during breastfeeding is limited, and it may pass into breast milk. Your doctor will weigh the potential risks and benefits.

Can BRITZILAM 75 Tablet be taken with other medications?

BRITZILAM 75 Tablet can interact with other medications. It's crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking. For example, brivaracetam levels may decrease when combined with other anti-epileptic medicines like carbamazepine and phenytoin. Antibiotics like rifampin can also reduce brivaracetam levels. Taking it with Central Nervous System (CNS) depressants such as opioids, antidepressants, or anti-anxiety medicines can increase drowsiness and sedation.

What precautions should be taken while taking BRITZILAM 75 Tablet?

Avoid consuming alcohol while taking BRITZILAM 75 Tablet, as it can increase drowsiness, dizziness, and other side effects. This medicine may cause drowsiness and dizziness, so avoid driving or operating heavy machinery until you understand how it affects you. Inform your doctor if you have liver or kidney problems, as dose adjustments may be necessary. Do not stop taking the medicine suddenly without consulting your doctor, as abrupt discontinuation can worsen seizures.

What happens if a dose of BRITZILAM 75 Tablet is missed?

If you miss a dose of BRITZILAM 75 Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one, as this may increase the risk of side effects.

How should BRITZILAM 75 Tablet be stored?

BRITZILAM 75 Tablet should be stored in a cool, dry place, away from direct sunlight and moisture. Keep it out of sight and reach of children. The typical storage temperature is between 10ºC and 25ºC or below 30ºC.