Macsita D 100/10 Mg Tablet ( 10 Tab )

MACSITA D 100/10 MG TABLET

Name:

• Brand Name: Macsita D 100/10 Tablet
• Common Name: Dapagliflozin and Sitagliptin Tablets

Composition: Each tablet contains:

• Dapagliflozin: 10 mg
• Sitagliptin: 100 mg

Uses: Macsita D 100/10 Tablet is prescribed for the management of type 2 diabetes mellitus in adults. It is used when blood sugar levels are not adequately controlled by diet and exercise alone. This medication can be used on its own or in combination with other anti-diabetic medications like metformin, sulfonylureas, or insulin. It helps control blood sugar levels by increasing glucose excretion through urine and improving insulin secretion while reducing glucose production by the liver. The medicine may also be effective in treating chronic kidney disease in adults with reduced kidney function and can reduce the risk of cardiovascular events.

Dosage and Administration: This medicine should be taken orally, usually once daily, as directed by a doctor. It can be taken with or without food, but it is recommended to take it at the same time each day for consistency. Tablets should be swallowed whole with water and not crushed or chewed. Adhere to the prescribed dosage and do not exceed it without consulting your doctor. Do not stop taking this medicine without consulting a healthcare provider, as this could lead to increased blood sugar levels and potential complications.

Side Effects: Common side effects may include:

• Urinary tract infection (UTI)
• Nasal congestion, sore throat, and upper respiratory tract infections
• Headaches, back pain, and joint pain
• Diarrhoea and nausea
• Genital fungal infections
• Dizziness or light-headedness Hypoglycemia (low blood sugar) can occur, especially when used with other antidiabetic medicines, alcohol, or if meals are delayed or missed.

Precautions:

• Pregnancy and Breastfeeding: Dapagliflozin is contraindicated during the second and third trimesters of pregnancy. It is not advised during breastfeeding as it may pass into breast milk.
• Medical Conditions: Inform your doctor about any kidney or liver problems, urinary tract infections, or if you are on diuretics. This medication is not suitable for individuals with type 1 diabetes mellitus or severe kidney/liver disease, or those undergoing dialysis.
• Alcohol: Alcohol can interfere with the effectiveness of Macsita D and affect blood sugar levels.
• Hygiene: Maintaining good hygiene can help prevent genital fungal infections.

Storage: Store Macsita D 100/10 Tablet below 30°C in a cool and dry place, away from direct sunlight. Keep out of the sight and reach of children.

MACSITA D 100/10 MG TABLET is a combination medicine containing Dapagliflozin (10 mg) and Sitagliptin (100 mg) that is used to manage type 2 diabetes mellitus.

What is MACSITA D 100/10 MG TABLET used for?

MACSITA D 100/10 MG TABLET is primarily used to manage type 2 diabetes mellitus in adults, particularly when blood sugar levels are not adequately controlled by diet and exercise alone, or when metformin monotherapy is insufficient. It helps improve blood sugar control and may also reduce the risk of heart attack, heart failure, and chronic kidney disease in adults.

How does MACSITA D 100/10 MG TABLET work?

This medicine works through two active ingredients:

• Dapagliflozin (10 mg), an SGLT2 inhibitor, works by blocking the reabsorption of glucose in the kidneys, leading to increased excretion of excess glucose through the urine and thus lowering blood glucose levels.
• Sitagliptin (100 mg), a DPP-4 inhibitor, works by preventing the breakdown of incretin hormones (like GLP-1 and GIP). This action increases insulin production from the pancreas when blood sugar is high and decreases the amount of glucose produced by the liver, contributing to better blood sugar control.

What is the usual dosage of MACSITA D 100/10 MG TABLET?

The dosage will be determined by your doctor based on your individual condition. It is crucial to take the medicine exactly as prescribed and not to alter the dosage without consulting your doctor. MACSITA D 100/10 Tablet can be taken with or without food, but it is recommended to take it at the same time each day to maintain consistent blood levels.

What are the possible side effects of MACSITA D 100/10 MG TABLET?

Common side effects can include headache, flatulence, constipation, stomach pain, diarrhea, nausea, back pain, joint pain, common cold, stuffy or runny nose, sore throat, and swelling of hands or legs. Urinary tract infections and genital fungal infections are also common due to increased glucose excretion in the urine. Rarely, serious side effects like pancreatitis or severe allergic reactions can occur.

Is MACSITA D 100/10 MG TABLET safe during pregnancy or breastfeeding?

MACSITA D 100/10 MG TABLET is generally not recommended during pregnancy, especially in the second and third trimesters, as Dapagliflozin is contraindicated during these periods. It is also advised against during breastfeeding, as the medication may pass into breast milk and potentially cause adverse effects in infants. Always consult your doctor for advice if you are pregnant, planning pregnancy, or breastfeeding.

Can MACSITA D 100/10 MG TABLET be taken with other medications?

Yes, it can be used in conjunction with other diabetes medications such as metformin, sulfonylureas, or insulin, but this may increase the risk of low blood sugar (hypoglycemia). It can interact with diuretics (water pills), which may increase the risk of dehydration and low blood pressure. Certain antibiotics (like gatifloxacin and ciprofloxacin) and oral contraceptives may also interact with this medicine. Always inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid potential drug interactions.

What precautions should be taken while taking MACSITA D 100/10 MG TABLET?

This medicine is not for type 1 diabetes mellitus. Caution is advised for individuals with severe kidney or liver disease, pancreatitis, gallstones, or a history of urinary tract infections. Avoid excessive alcohol consumption as it can increase the risk of side effects, including hypoglycemia and diabetic ketoacidosis. Maintain good hygiene to prevent genital fungal and urinary tract infections. Regular monitoring of blood sugar levels is important. Do not stop taking the medicine abruptly without consulting your doctor, as this can lead to increased blood sugar levels and complications. If you experience dizziness, exercise caution when driving or operating machinery. It is not recommended for children under 18 years of age.

What happens if a dose of MACSITA D 100/10 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should MACSITA D 100/10 MG TABLET be stored?

Store MACSITA D 100/10 MG TABLET at room temperature, ideally below 30°C. Keep it in its original packaging to protect it from light and moisture. Keep it out of the sight and reach of children.