Oxra 5 Mg Tablet (14 Tab)

OXRA 5 MG TABLET

OXRA 5 MG TABLET, manufactured by SUN PHARMA LABORATORIES LTD., is a medication primarily used for the management of type 2 diabetes mellitus, heart failure, and chronic kidney disease.

• Composition OXRA 5 MG TABLET contains Dapagliflozin (5 mg) as its active ingredient. Dapagliflozin is a sodium-glucose co-transporter-2 (SGLT-2) inhibitor, which works by blocking the reabsorption of glucose in the kidneys, thereby leading to the excretion of excess sugar from the body through urine. This action helps lower blood sugar levels, protects kidney function, and reduces the strain on the heart.

• Uses

  • Type 2 Diabetes Mellitus: It is prescribed to control high blood sugar levels in adults with type 2 diabetes, often when diet and exercise alone are insufficient.
  • Heart Failure: It is used in adults with heart failure, particularly those with reduced ejection fraction, to improve heart function and reduce the risk of hospitalization.
  • Chronic Kidney Disease: This medicine is also indicated for adults with chronic kidney disease and reduced kidney function to help protect the kidneys and slow down the progression of the disease.

• Dosage and Administration OXRA 5 MG TABLET should be taken orally once daily, with or without food, as directed by a healthcare professional. It is recommended to take the tablet at a fixed time each day. The tablet should be swallowed whole and not crushed, chewed, or broken. The dosage may vary based on individual patient factors, and a doctor may initially prescribe a lower dose which can be adjusted. Do not exceed the prescribed dose.

• Side Effects

  • Common Side Effects: Low blood sugar (hypoglycemia, especially when used with insulin or sulfonylureas), genital fungal infections (thrush, with symptoms like irritation, itching, unusual discharge, or odor), urinary tract infections (UTIs), increased urination or frequency of urination, back pain, dizziness, rash, increased thirst, and nausea.
  • Serious Side Effects: Seek immediate medical attention if you experience signs of diabetic ketoacidosis (such as nausea, vomiting, stomach pain, excessive thirst, confusion, sweet-smelling breath, or rapid weight loss) or severe allergic reactions (like swelling of the face, tongue, or throat, leading to difficulty breathing).

• Precautions

  • Allergies: Do not use if you are allergic to dapagliflozin or any other ingredients in OXRA 5 MG TABLET.
  • Medical History: Inform your doctor about any history of liver or kidney problems (caution is advised, especially with severe kidney disease or bladder cancer), type 1 diabetes (this medication is not for type 1 diabetes), heart conditions, severe low blood pressure, or conditions that can lead to dehydration (e.g., severe vomiting, fever, or prior to surgery).
  • Pregnancy and Breastfeeding: OXRA 5 MG TABLET is generally not recommended during pregnancy, particularly in later stages, or while breastfeeding. Consult your doctor if you are pregnant, planning pregnancy, or breastfeeding.
  • Alcohol Consumption: Avoid consuming alcohol as it may affect blood glucose levels.
  • Driving and Machinery: Dizziness or fluctuations in blood sugar levels can impair your ability to drive or operate machinery. Exercise caution.
  • Pediatric Use: This medicine is not recommended for individuals under 18 years of age.
  • Drug Interactions: Inform your doctor about all other medications, supplements, or herbal products you are taking, especially diuretics or other antidiabetic agents like insulin or sulfonylureas, as dose adjustments may be necessary. Note that this medicine can interfere with urine glucose tests and 1,5-anhydroglucitol (1,5-AG) assays, making them unreliable for monitoring glycemic control.

• Storage Store OXRA 5 MG TABLET at room temperature, typically between 20°C to 25°C (or 10°C to 25°C, or below 30°C). Protect it from light and moisture. Keep the medicine out of the reach of children. Do not use the medicine after its expiry date.

What is OXRA 5 MG TABLET used for?

OXRA 5 MG TABLET, which contains Dapagliflozin, is primarily used to treat type 2 diabetes mellitus, alongside a balanced diet and regular exercise. It is also prescribed for adults with heart failure where the heart's pumping ability is reduced, and for chronic kidney disease to help protect kidney function and reduce the risk of worsening conditions.

How does OXRA 5 MG TABLET work?

OXRA 5 MG TABLET belongs to a class of medicines called sodium-glucose cotransporter 2 (SGLT2) inhibitors. It works by blocking the action of SGLT2 proteins in the kidneys, which normally reabsorb glucose. By inhibiting this action, the medicine helps the body remove excess sugar through the urine, thereby lowering blood sugar levels. Additionally, it helps reduce the strain on the heart, allowing it to pump blood more efficiently, and protects the kidneys from further damage.

What is the usual dosage for OXRA 5 MG TABLET?

The usual dosage for OXRA 5 MG TABLET is once daily, as prescribed by your doctor. It can be taken with or without food, but it is recommended to take it at the same time each day for consistent results. Your doctor may start with a 5 mg dose and may increase it up to 10 mg once daily based on your condition and response to treatment.

What are the possible side effects of OXRA 5 MG TABLET?

Common side effects can include urinary tract infections (UTIs), increased urination, genital yeast infections (thrush) in both males and females, back pain, dizziness, rash, and increased thirst. In some cases, low blood sugar (hypoglycemia) can occur, especially when taken with other antidiabetic medications like insulin or sulfonylureas. Most of these side effects are temporary; however, if they persist or worsen, consult your doctor.

Is OXRA 5 MG TABLET safe during pregnancy or breastfeeding?

OXRA 5 MG TABLET is generally not recommended for use during pregnancy, especially in the later stages, as it may pose risks to the developing baby. It is also not recommended while breastfeeding, as it is unclear if the medication passes into breast milk. Always inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding before starting this medication.

Can OXRA 5 MG TABLET be taken with other medications?

OXRA 5 MG TABLET can interact with certain medications. It is crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking. Particular caution is advised with diuretics (water pills), insulin, or sulfonylureas, as combining them with OXRA 5 MG TABLET can increase the risk of low blood sugar.

What precautions should be taken while on OXRA 5 MG TABLET?

Before taking OXRA 5 MG TABLET, inform your doctor if you have kidney or liver problems, severe dehydration, a history of bladder cancer, or type 1 diabetes. It is advisable to avoid alcohol consumption, as it can affect blood sugar levels. Regular monitoring of blood sugar levels is recommended. Maintaining good personal hygiene can help prevent genital fungal infections, which are a possible side effect.

What happens if a dose of OXRA 5 MG TABLET is missed?

If you miss a dose of OXRA 5 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should OXRA 5 MG TABLET be stored?

OXRA 5 MG TABLET should be stored at room temperature, typically between 10ºC to 25ºC or below 30ºC. Keep the medicine in a cool and dry place, away from direct sunlight and moisture. Ensure it is kept out of the sight and reach of children.