Zilarbi 80 Mg ( 10 Tablet )

ZILARBI 80 MG Tablet

ZILARBI 80 MG Tablet, manufactured by EMCURE PHARMACEUTICALS LTD., is an angiotensin II receptor blocker (ARB) primarily used for managing high blood pressure.

• Name

  • Brand Name: ZILARBI 80 MG
  • Common Name: Azilsartan (as Azilsartan medoxomil)

• Composition

  • Each tablet contains 80 mg of Azilsartan medoxomil, which is converted to the active metabolite azilsartan in the body.

• Uses ZILARBI 80 MG Tablet is prescribed for:

  • Management of high blood pressure (hypertension), either alone or in combination with other antihypertensive medicines.
  • Reducing the risk of severe heart problems, including heart attacks and strokes.
  • Assisting in preserving kidney function, particularly in patients with diabetes.

• Dosage and Administration

  • ZILARBI 80 MG Tablet is typically taken orally once daily.
  • It can be administered with or without food, and should be swallowed whole with an adequate amount of water.
  • For optimal benefit, it is recommended to take the tablet at the same time each day.
  • The dose and duration of treatment are determined by the doctor based on the patient's condition. A starting dose of 40 mg may be considered for patients who are volume- or salt-depleted or on high doses of diuretics.
  • Do not stop taking this medicine abruptly without consulting a doctor, as it may cause blood pressure to increase.

• Side Effects Common side effects may include:

  • Dizziness
  • Fatigue/Tiredness
  • Diarrhea
  • Nausea
  • Muscle spasms
  • Low blood pressure (hypotension), which can lead to feeling dizzy or faint
  • Increased serum creatinine (a waste product usually removed by kidneys)
  • Hyperkalemia (too much potassium in the blood)
  • Skin rash and itching Consult a doctor if any side effects worsen or if serious effects like angioedema (swelling of the face, lips, tongue, and/or throat) occur.

• Precautions

  • Pregnancy: ZILARBI 80 MG is not recommended during pregnancy and should be discontinued if pregnancy is detected, as it may cause serious harm to the baby.
  • Allergies: Do not take if allergic to azilsartan or any other ingredients in the tablet.
  • Diabetes/Kidney Disorders: Avoid use if you have diabetes or kidney-related disorders and are taking blood pressure-lowering medicines like aliskiren.
  • Alcohol: Avoid alcohol consumption during treatment as it may lower blood pressure and lead to dizziness or drowsiness.
  • Potassium: Avoid supplements containing potassium or potassium-rich foods, as azilsartan can increase blood potassium levels. Regular blood tests to monitor potassium levels may be performed.
  • Drug Interactions: Inform your doctor about all medications, including other blood pressure medicines (e.g., ACE inhibitors, aliskiren), lithium, and Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) such as ibuprofen or naproxen, as they can interact with ZILARBI 80 MG.
  • Medical Conditions: Use with caution in patients with liver problems, kidney health concerns, severe hepatic impairment, renal artery stenosis, or severe aortic stenosis. Inform your doctor about your medical history, especially if you have dehydration or heart problems.
  • Driving/Operating Machinery: ZILARBI 80 MG may cause dizziness, so caution is advised when driving or operating machinery until you know how the medicine affects you.

• Storage

  • Store in a cool and dry place.
  • Keep out of the sight and reach of children.

What is ZILARBI 80 MG used for?

ZILARBI 80 MG Tablet is primarily used for the treatment of high blood pressure (hypertension), either alone or in combination with other antihypertensive medicines. It also helps to reduce the risk of severe heart problems, including heart attacks and strokes. Additionally, it can assist in preserving kidney function in patients with diabetes.

How does ZILARBI 80 MG work?

ZILARBI 80 MG contains Azilsartan medoxomil, which belongs to a class of medications called Angiotensin II Receptor Blockers (ARBs). Angiotensin II is a natural substance in the body that causes blood vessels to narrow, leading to increased blood pressure. ZILARBI 80 MG works by blocking the binding of Angiotensin II to its receptors, thereby causing blood vessels to relax and widen. This action lowers blood pressure and allows blood to flow more smoothly.

What is the usual dosage of ZILARBI 80 MG?

The recommended dose for adults is typically 80 mg taken orally once daily. Your doctor will determine the appropriate dose and duration of treatment based on your health condition. It can be taken with or without food, but it is recommended to take it at the same time each day for better blood pressure control. For patients taking high doses of diuretics, a starting dose of 40 mg may be considered.

What are the possible side effects of ZILARBI 80 MG?

Common side effects of ZILARBI 80 MG may include dizziness, diarrhea, low blood pressure (hypotension), nausea, muscle spasms, skin rash, itching, and fatigue. Some individuals may also experience an increase in serum creatinine (a waste product removed by kidneys) or hyperkalemia (increased potassium levels in the blood). If you experience severe diarrhea, significant weight loss, or any other bothersome or persistent side effects, consult your doctor immediately.

Is ZILARBI 80 MG safe during pregnancy or breastfeeding?

ZILARBI 80 MG is considered unsafe to use during pregnancy, especially during the second and third trimesters, as it can cause serious harm or even death to the developing baby. If pregnancy is detected, the medicine should be discontinued as soon as possible. It is also not recommended during breastfeeding due to limited information on its safety and potential harm to the baby. It is advised to consult your doctor for safer alternatives if you are breastfeeding.

Can ZILARBI 80 MG be taken with other medications?

Yes, ZILARBI 80 MG can interact with certain medications. Inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid possible interactions. Specifically, caution should be exercised with:

• Other blood pressure-lowering medicines (e.g., ACE inhibitors like ramipril, lisinopril, enalapril): Co-administration may increase the risk of low blood pressure and high potassium levels.
• Aliskiren: Its use is contraindicated in patients with diabetes or kidney-related disorders who are also taking aliskiren.
• Painkillers (NSAIDs like ibuprofen, naproxen): These can reduce the blood pressure-lowering effect of ZILARBI 80 MG and may worsen kidney function.
• Potassium supplements or potassium-rich foods: ZILARBI 80 MG can increase blood potassium levels, so these should be avoided or monitored closely.
• Lithium-based medicines: ZILARBI 80 MG may elevate lithium levels, potentially leading to toxicity.
• Water pills (diuretics).

What precautions should be taken while using ZILARBI 80 MG?

Before taking ZILARBI 80 MG, inform your doctor if you have any underlying medical conditions, such as heart disorders, kidney disease (including kidney transplant or renal artery stenosis), liver disease (especially severe), diabetes, or low blood pressure.

Avoid consuming alcohol during treatment, as it can further lower your blood pressure and cause dizziness or drowsiness. ZILARBI 80 MG may cause dizziness or tiredness, so avoid driving or operating heavy machinery until you know how the medicine affects you. Do not stop taking ZILARBI 80 MG suddenly without consulting your doctor, as this can lead to a rise in blood pressure. Your doctor may recommend regular monitoring of your kidney function, blood pressure, and potassium levels while on this medication.

What happens if a dose of ZILARBI 80 MG is missed?

If you miss a dose of ZILARBI 80 MG, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one. Missing a dose may lead to a temporary rise in blood pressure.

How should ZILARBI 80 MG be stored?

ZILARBI 80 MG tablets should be stored in a cool and dry place, below 30°C, and kept out of the sight and reach of children. The tablets are hygroscopic and require protection from moisture.