Pregeb M Od 75 Mg Tablet (15 Tab)

PREGEB M OD 75 MG TABLET

PREGEB M OD 75 MG TABLET by TORRENT PHARMACEUTICALS LTD. is a combination medicine used primarily for managing neuropathic pain.

• Name:

  • Brand Name: PREGEB M OD 75 MG TABLET
  • Common Name: Pregabalin and Methylcobalamin extended-release tablet

• Composition:

  • Active Ingredients: Each tablet contains Pregabalin (75 mg) and Methylcobalamin (1500 mcg or 1.5 mg). Pregabalin acts as an anticonvulsant that reduces pain signals, while Methylcobalamin (a form of Vitamin B12) helps in the regeneration and protection of damaged nerve cells by promoting myelin production.

• Uses: PREGEB M OD 75 MG TABLET is prescribed for various conditions related to nerve damage and neurological disorders, including:

  • Neuropathic pain (nerve pain) caused by diabetes (diabetic neuropathy), shingles (postherpetic neuralgia), spinal cord injury, and sciatica.
  • Management of fibromyalgia (musculoskeletal pain).
  • As an adjunct therapy for adult patients with partial onset of seizures.
  • May also help in anxiety relief, mood stabilization, and improving sleep quality.

• Dosage and Administration: Typically, the recommended dosage is one tablet twice a day, taken orally with water, with or without food, as advised by your doctor. It is crucial to swallow the tablet whole and not to crush, chew, or break it. Do not discontinue treatment abruptly without consulting your doctor.

• Side Effects: Common side effects include dizziness, drowsiness, headache, nausea, vomiting, diarrhea, loss of appetite, blurred vision, sweating, dry mouth, fluid retention, weight gain, and fatigue. Serious side effects that require immediate medical attention include severe allergic reactions (rash, swelling of face/lips/throat, difficulty breathing), unexplained muscle pain/weakness (elevated creatine kinase), and decreased urination (potential kidney failure).

• Precautions:

  • Pregnancy and Breastfeeding: Not generally recommended during pregnancy or breastfeeding unless the benefits clearly outweigh the risks, as it may be unsafe.
  • Alcohol: Avoid alcohol consumption as it can increase drowsiness and other central nervous system side effects.
  • Driving/Operating Machinery: May cause dizziness or drowsiness, so avoid activities requiring concentration until you understand how it affects you.
  • Medical Conditions: Use with caution in patients with kidney disease, heart disease, liver disease, a history of angioedema, or drug dependence.
  • Children: Not recommended for individuals under 18 years of age.

• Storage: Store in a cool and dry place, away from direct sunlight and moisture, preferably at temperatures between 10ºC to 25ºC or below 30ºC. Keep out of sight and reach of children.

What is PREGEB M OD 75 MG Tablet used for?

PREGEB M OD 75 MG Tablet is a combination medicine primarily used to treat neuropathic pain, which is nerve pain resulting from damage or malfunctioning of the nervous system. This includes conditions such as diabetic neuropathy, postherpetic neuralgia (nerve pain after shingles), and peripheral neuropathy. It may also be used as an adjunct therapy for partial-onset seizures and fibromyalgia, and can help with anxiety relief, general pain management, and sleep disturbances.

How does PREGEB M OD 75 MG Tablet work?

This medicine contains two active ingredients: Pregabalin (75 mg) and Methylcobalamin (1500 mcg or 1.5 mg). Pregabalin is an anticonvulsant that works by decreasing the pain signals sent by damaged nerves in the body by modulating calcium channel activity in nerve cells. Methylcobalamin, a form of Vitamin B12, helps to rejuvenate and protect damaged nerve cells by promoting the production of myelin, the protective outer layer of nerve cells, and supports nerve regeneration.

What is the usual dosage for PREGEB M OD 75 MG Tablet?

PREGEB M OD 75 MG Tablet should be taken exactly as prescribed by your doctor. The "OD" in the name typically indicates "once daily". The dosage may vary depending on your specific condition and response to treatment. It can generally be taken with or without food, but consistency is recommended. Do not exceed the prescribed dosage without consulting your doctor.

What are the possible side effects of PREGEB M OD 75 MG Tablet?

Common side effects include dizziness, drowsiness, headache, nausea, vomiting, diarrhea, increased or loss of appetite, weight gain, blurred vision, dry mouth, fatigue, and swelling in the hands or feet (edema). Less common but serious side effects can include allergic reactions (e.g., swelling of the face, lips, tongue, difficulty breathing), suicidal thoughts, and an increased risk of heart failure. If you experience any severe or persistent side effects, contact your doctor immediately.

Is PREGEB M OD 75 MG Tablet safe during pregnancy or breastfeeding?

PREGEB M OD 75 MG Tablet is generally not recommended during pregnancy unless clearly necessary and advised by a doctor, as its safety and efficacy in pregnant women have not been fully established, and animal studies suggest potential reproductive toxicity. It is categorized as a Category C medicine. For breastfeeding mothers, caution is advised, and it is generally not recommended as it is unknown if the medicine passes into breast milk and could potentially harm the infant. Always consult your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Can PREGEB M OD 75 MG Tablet be taken with other medications?

PREGEB M OD 75 MG Tablet can interact with other medications. It is crucial to inform your doctor about all prescription and over-the-counter medicines, vitamins, and herbal supplements you are currently taking. Interactions can occur with opioids (e.g., oxycodone), antianxiety drugs (e.g., lorazepam), antidiabetic medicines (e.g., pioglitazone, rosiglitazone), certain antihypertensive medications, and other central nervous system (CNS) depressants, potentially increasing side effects like dizziness and sleepiness. Alcohol consumption should be avoided as it can worsen these side effects.

What precautions should be taken while using PREGEB M OD 75 MG Tablet?

Do not stop taking this medicine abruptly, as sudden discontinuation can lead to withdrawal symptoms such as trouble sleeping, headaches, anxiety, or even convulsions. The dosage should be gradually reduced under medical supervision. Since this medication can cause dizziness and drowsiness, avoid driving or operating heavy machinery until you understand how it affects you. Exercise caution if you have a history of heart disease, kidney problems (dose adjustments may be necessary), liver disease, alcoholism, drug abuse, or suicidal thoughts. Inform your doctor if you are diabetic and notice weight gain, as your diabetic medications may need adjustment. It is not recommended for children and adolescents under 18 years of age.

What happens if a dose of PREGEB M OD 75 MG Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the forgotten one, as this may increase the risk of side effects. Missing doses, particularly if you have epilepsy, may trigger a seizure.

How should PREGEB M OD 75 MG Tablet be stored?

Store PREGEB M OD 75 MG Tablet in a cool, dry place, typically below 30°C, away from direct sunlight and moisture. Keep the medication out of the sight and reach of children and pets.