Zoryl M Forte 4 Mg Tablet (15 Tab)

ZORYL M FORTE 4 MG TABLET by INTAS PHARMACEUTICALS LTD.

Name

• Brand Name: ZORYL M FORTE 4 MG TABLET, Zoryl-M 4 Forte Tablet PR
• Common Name: Glimepiride and Metformin Hydrochloride Tablets

Composition

ZORYL M FORTE 4 MG TABLET contains a combination of two active ingredients:

• Glimepiride: 4 mg
• Metformin: 1000 mg (or 1G)

Uses

This medicine is primarily prescribed for the treatment of Type 2 Diabetes Mellitus in adults. It is used as an adjunct to diet and exercise to improve glycemic control, especially when blood sugar levels are not adequately controlled by diet and exercise alone, or with a single anti-diabetic agent. Zoryl-M 4 Forte Tablet helps manage blood glucose levels, enhances insulin sensitivity, and reduces the risk of serious diabetes-related complications such as kidney damage, eye problems, nerve issues, and cardiovascular diseases.

Dosage and Administration

ZORYL M FORTE 4 MG TABLET should be taken orally, typically once daily with a meal, or as prescribed by a physician. It is important to swallow the tablet whole with a glass of water and not to chew, crush, or break it. The dosage may be adjusted by the doctor based on individual factors like the seriousness of the condition and blood glucose levels. Do not exceed the recommended dose.

Side Effects

Common Side Effects:

• Hypoglycemia (low blood sugar level), symptoms include headache, dizziness, weakness, sweating, hunger, irritability, fast heartbeat, confusion.
• Gastrointestinal symptoms: Nausea, vomiting, diarrhea, stomach pain, metallic taste.
• Headache
• Altered taste

Serious Side Effects (Rare):

• Lactic Acidosis (accumulation of lactic acid in the body), characterized by muscle pain or weakness, dizziness, tiredness, feeling cold in arms and legs, difficulty breathing, persistent nausea, vomiting, or stomach pain, and slow heart rate.
• Vitamin B12 deficiency (with long-term use)
• Signs of reduced red blood cells, platelets, or white blood cells
• Skin rashes, redness, itching, and hives

Precautions

• Allergies: Do not take if allergic to any components of the medicine.
• Pregnancy and Breastfeeding: Not recommended during pregnancy as it may harm the unborn baby, and should be avoided by nursing mothers as it may pass into breast milk.
• Alcohol Consumption: Avoid excessive alcohol intake due to an increased risk of lactic acidosis and hypoglycemia.
• Liver and Kidney Conditions: Use with caution in patients with liver problems; dose adjustment may be necessary. Not recommended for patients with severe kidney disease; regular monitoring of kidney function is advisable.
• Hypoglycemia: Be aware of the symptoms of low blood sugar and carry a fast-acting source of glucose (e.g., candies, glucose biscuits).
• Driving and Operating Machinery: May decrease alertness; drive only if alert.
• Drug Interactions: Inform your doctor about all other medications, including antidiabetic medications, diuretics, corticosteroids, thyroid medicines, oral contraceptives, and ACE inhibitors, to avoid undesirable effects.
• Surgery: Inform your doctor about your diabetes treatment if you are due to have surgery under general anesthetic.

Storage

Store in a cool, dry, and dark place, ideally between 10°C to 25°C or below 30°C. Protect the medicine from direct light and moisture. Keep it out of reach and sight of children and pets.

ZORYL M FORTE 4 MG TABLET (15 TAB) by INTAS PHARMACEUTICALS LTD. is a combination medicine containing Glimepiride and Metformin, primarily used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels when diet and exercise alone are not sufficient.

Here are some frequently asked questions about ZORYL M FORTE 4 MG TABLET:

What is ZORYL M FORTE 4 MG TABLET used for?

ZORYL M FORTE 4 MG TABLET is used to treat type 2 diabetes mellitus in adults. It is prescribed when diet, exercise, and a single anti-diabetic medicine are not enough to control blood sugar levels. This medication helps manage blood glucose levels and can reduce the risk of serious diabetes-related complications such as kidney damage, eye damage, nerve problems, and loss of limbs.

How does ZORYL M FORTE 4 MG TABLET work?

This medicine is a combination of two anti-diabetic drugs: Glimepiride and Metformin.

• Glimepiride is a sulfonylurea that works by stimulating the beta cells in the pancreas to produce and release more insulin, which helps lower blood glucose levels.
• Metformin is a biguanide that works by reducing the production of glucose in the liver, delaying the absorption of glucose from the intestines, and increasing the body's sensitivity to insulin.

What is the usual dosage of ZORYL M FORTE 4 MG TABLET?

ZORYL M FORTE 4 MG TABLET should be taken with food, usually once a day, or as directed by your doctor. Your doctor will determine the appropriate dose based on your individual blood sugar levels and how you respond to the medication. It's crucial to follow the prescribed dosage and not to exceed it without consulting your doctor.

What are the possible side effects of ZORYL M FORTE 4 MG TABLET?

Common side effects include hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, and headache. Other possible side effects include vomiting and a metallic taste in the mouth. Long-term use can sometimes lead to vitamin B12 deficiency. A rare but serious side effect is lactic acidosis, which requires immediate medical attention if symptoms like muscle pain, weakness, dizziness, or difficulty breathing occur.

Is ZORYL M FORTE 4 MG TABLET safe during pregnancy or breastfeeding?

ZORYL M FORTE 4 MG TABLET is generally not recommended for use during pregnancy as it may be unsafe and could harm the unborn baby. It is also considered unsafe to use while breastfeeding, as it may pass into breast milk and cause adverse effects in the baby. Always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Can ZORYL M FORTE 4 MG TABLET be taken with other medications?

ZORYL M FORTE 4 MG TABLET can interact with several other medications. For example, other anti-diabetic medications (like insulin), diuretics, corticosteroids, thyroid medicines, oral contraceptives, and certain antibiotics, antifungals, and heart medications can affect its effectiveness or increase the risk of side effects. It's essential to inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid potential interactions.

What precautions should be taken with ZORYL M FORTE 4 MG TABLET?

• Hypoglycemia: Be aware of the signs of low blood sugar (e.g., sweating, dizziness, headache, shakiness) and carry a fast-acting source of glucose (like glucose tablets, honey, or fruit juice) with you.
• Alcohol: Avoid alcohol consumption as it can increase the risk of low blood sugar and lactic acidosis.
• Kidney and Liver Disease: Use with caution if you have kidney or liver disease, and inform your doctor, as dose adjustments or avoiding the medicine may be necessary, especially in severe cases.
• Surgery: Inform your doctor about your diabetes treatment if you are scheduled for surgery.
• Vitamin B12: Long-term use may lead to vitamin B12 deficiency.
• Driving: Your ability to drive may be affected if your blood sugar is too low or too high, so exercise caution.

What happens if a dose of ZORYL M FORTE 4 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one, as this can lead to low blood sugar.

How should ZORYL M FORTE 4 MG TABLET be stored?

Store ZORYL M FORTE 4 MG TABLET in a cool, dry, and dark place, ideally below 30°C. Keep it in its original packaging, tightly closed, and away from direct light and moisture to maintain its effectiveness. Always keep this medicine out of the reach of children and pets.