Empahope L 10mg Tab

EMPAHOPE L 10MG TAB

Name:

• Common Name: Empahope L 10mg Tablet
• Brand Name: Empahope L 10mg (Manufactured by Macleods Pharmaceuticals Ltd.)

Composition: Each tablet contains a combination of two active ingredients:

• Empagliflozin: 10 mg
• Linagliptin: 5 mg

Uses: EMPAHOPE L 10MG TAB is primarily used for the treatment of Type 2 Diabetes Mellitus in adults. It is prescribed to improve blood sugar control, especially when diet and exercise alone are not sufficient. This medication also helps to reduce the risk of cardiovascular events, such as heart attack and heart failure, and prevent serious diabetes complications like kidney damage, eye damage (retinopathy), nerve damage (neuropathy), diabetic foot ulcers, and delayed wound healing in adults with type 2 diabetes who also have cardiovascular disease.

Dosage and Administration: EMPAHOPE L 10MG TAB is taken orally, typically as one tablet once daily. It can be taken with or without food, but for best results, it should be taken at the same time each day. The specific dosage will be determined by a healthcare professional. It is crucial not to stop taking the medication suddenly without consulting a doctor, as this can lead to a spike in blood sugar levels and serious complications.

Side Effects: Common side effects may include:

• Urinary tract infections
• Nasopharyngitis (common cold symptoms)
• Upper respiratory tract infections
• Frequent urination
• Cough
• Rash and itching
• Low blood sugar levels (hypoglycemia), particularly when used with insulin or sulfonylureas, or with alcohol.
• Dizziness or light-headedness

Precautions:

• Contraindications: EMPAHOPE L 10MG TAB is not for individuals with Type 1 Diabetes Mellitus. It should also be avoided in patients with severe kidney or liver disease, or known allergies to empagliflozin or linagliptin.
• Interactions: Inform your doctor about all medicines, supplements, or herbal products being taken to avoid possible interactions. Concomitant use with insulin or sulfonylureas may increase the risk of hypoglycemia. Alcohol consumption should be limited or avoided, as it can heighten the risk of low blood sugar and dehydration.
• Specific Conditions: Use with caution in patients with kidney problems, dehydration, pancreatitis, gallstones, low blood pressure, heart failure, high cholesterol, yeast infections, blocked blood vessels, nerve problems, foot sores, or those undergoing amputation. Pregnant or breastfeeding women should consult their doctor before use. It is generally not recommended for children below 18 years of age or individuals over 75 years.
• Monitoring: Regular monitoring of blood sugar levels and kidney function is important during treatment. Staying well-hydrated is also recommended to prevent dehydration.

Storage: Store EMPAHOPE L 10MG TAB at room temperature, typically below 30°C or between 20°C to 25°C. Keep the medication away from moisture, excessive heat, and direct light. Ensure it is kept out of the reach of children and pets. Do not use the medication past its expiration date.

What is EMPAHOPE L 10MG TAB used for?

EMPAHOPE L 10MG TAB is a combination medicine primarily used to treat type 2 diabetes mellitus in adults. It is prescribed when diet and exercise alone are not sufficient to control blood sugar levels. Additionally, it helps prevent serious complications of diabetes, such as kidney damage, eye damage, nerve problems, and diabetic foot ulcers, and can reduce the risk of cardiovascular death in patients with type 2 diabetes and established cardiovascular disease. It may also be used in adults with chronic kidney disease to lower the risk of worsening kidney disease, end-stage kidney disease, cardiovascular death, and hospitalization for heart failure.

How does EMPAHOPE L 10MG TAB work?

EMPAHOPE L 10MG TAB contains two active ingredients: Empagliflozin and Linagliptin. Empagliflozin works by inhibiting the sodium-glucose co-transporter-2 (SGLT-2) in the kidneys. This action reduces the reabsorption of glucose back into the bloodstream and increases its excretion through urine, thereby lowering blood sugar levels. Linagliptin works by increasing the levels of natural substances called incretins, which help regulate blood sugar levels. It does this by stimulating insulin release, especially after meals, and by decreasing the amount of sugar the liver produces.

What is the usual dosage of EMPAHOPE L 10MG TAB?

EMPAHOPE L 10MG TAB usually comes in a strength containing 10mg of empagliflozin and 5mg of linagliptin. The typical dose is one tablet taken once a day. It can be taken at any time of day, with or without food, but it is recommended to take it at the same time each day. Your doctor will determine the specific dosage and may adjust it based on your individual needs and response to the therapy.

What are the possible side effects of EMPAHOPE L 10MG TAB?

Common side effects can include genital yeast infections (in both men and women), urinary tract infections, frequent urination, thirst, dizziness, and lightheadedness. More serious, though rare, side effects may include diabetic ketoacidosis (a serious condition with high ketone levels in the blood), acute kidney injury, Fournier's gangrene (a rare but severe bacterial infection of the perineum), and allergic reactions.

Is EMPAHOPE L 10MG TAB safe during pregnancy or breastfeeding?

EMPAHOPE L 10MG TAB (empagliflozin and linagliptin) is generally not recommended during pregnancy, especially during the second and third trimesters, due to potential risks to the unborn baby, including harm to kidney development. Similarly, it is not usually recommended while breastfeeding because it is unknown how much passes into breast milk and the theoretical risk to the infant's developing kidneys. It is crucial to discuss your pregnancy or breastfeeding plans with your doctor, who may recommend alternative medications.

Can EMPAHOPE L 10MG TAB be taken with other medications?

Yes, EMPAHOPE L 10MG TAB can be taken with other medications, but it's important to inform your doctor about all prescription, over-the-counter drugs, vitamins, and herbal supplements you are taking. Combining it with other blood sugar-lowering medications like insulin or sulfonylureas can increase the risk of hypoglycemia (low blood sugar), and your doctor may need to adjust their dosages. Diuretics (water pills) or blood pressure medications taken with EMPAHOPE L may increase the risk of dehydration and low blood pressure.

What precautions should be taken while using EMPAHOPE L 10MG TAB?

Before taking EMPAHOPE L 10MG TAB, inform your doctor if you have kidney or liver problems, a history of urinary tract infections, pancreatitis, or if you regularly consume alcohol. You should also be cautious about dehydration, especially if you experience severe nausea, vomiting, or diarrhea. Your doctor may advise temporarily stopping the medication before surgery or during periods of reduced food intake or fluid loss. It is important to monitor for symptoms of diabetic ketoacidosis and seek immediate medical attention if they occur.

What happens if a dose of EMPAHOPE L 10MG TAB is missed?

If you miss a dose of EMPAHOPE L 10MG TAB, take it as soon as you remember, unless it is less than 12 hours until your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should EMPAHOPE L 10MG TAB be stored?

EMPAHOPE L 10MG TAB should be stored in a closed container at room temperature, ideally between 68°F to 77°F (20°C to 25°C), away from heat, moisture, and direct light. Keep it from freezing and out of the reach of children.