Flozen Aa Tab

FLOZEN AA TAB by MANKIND PHARMA LTD is a combination medicine widely used for its pain-relieving, anti-inflammatory, and anti-swelling properties.

Name

• Brand Name: Flozen-AA Tablet
• Common Name: Aceclofenac, Paracetamol, and Serratiopeptidase combination.

Composition Each tablet of Flozen-AA contains three active ingredients:

• Aceclofenac (100mg) - A non-steroidal anti-inflammatory drug (NSAID) that works by blocking cyclo-oxygenase (COX) enzyme, which is responsible for pain and swelling.
• Paracetamol (325mg) - An analgesic (pain reducer) and antipyretic (fever reducer) that enhances pain relief. (Note: One source states Paracetamol 500mg, but multiple other sources confirm 325mg, so 325mg is used).
• Serratiopeptidase (15mg) - An enzyme that helps reduce inflammation and promotes healing by breaking down abnormal proteins and thinning fluids around the injury site, facilitating fluid drainage.

Uses Flozen-AA Tablet is prescribed for short-term relief from pain, inflammation, and swelling in various conditions, including:

• Rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
• Bone and soft tissue injuries.
• Post-operative inflammation, oedema (swelling), and pain.
• Headaches, toothaches, menstrual cramps, and musculoskeletal pain.
• Fever and cold symptoms.

Dosage and Administration Flozen-AA Tablet should be taken at the dose and duration advised by your doctor.

• It is generally recommended to take the tablet with food or milk to avoid stomach upset.
• Swallow the tablet whole with a glass of water; do not chew, crush, or break it.
• Typically, the dosage for conditions like back pain might be one tablet daily, but this can vary. It is important not to exceed the prescribed dosage.

Side Effects Common side effects may include:

• Nausea, vomiting, stomach pain, indigestion, heartburn, loss of appetite, and diarrhea.
• Dizziness and drowsiness.
• Increased liver enzymes.

Serious complications like stomach bleeding and kidney problems can occur with long-term use. If side effects persist or worsen, consult a doctor.

Precautions

• Allergies: Avoid if allergic to aceclofenac, paracetamol, serratiopeptidase, or other NSAIDs like aspirin or ibuprofen.
• Pregnancy and Breastfeeding: Not recommended for pregnant or breastfeeding women.
• Alcohol: Avoid alcohol consumption as it may increase the risk of liver damage and excessive drowsiness.
• Pre-existing Conditions: Use with caution in patients with a history of stomach ulcers, gastric bleeding, severe heart failure, high blood pressure, liver or kidney disease, diabetes, or inflammatory bowel diseases. Regular monitoring of kidney and liver function may be necessary during long-term treatment.
• Drug Interactions: Inform your doctor about all current medications, supplements, or herbal products to avoid potential interactions, especially with anticoagulants, anti-platelet agents, other NSAIDs, and certain blood pressure medications.
• Driving/Operating Machinery: May cause dizziness and sleepiness, so avoid driving or activities requiring mental focus until you know how the medicine affects you.
• Children: Not recommended for use in children and adolescents below 18 years.

Storage

• Store below 30°C in a cool, dry place.
• Keep shielded from direct light and moisture.
• Keep out of reach of children and pets.

FLOZEN AA TAB by Mankind Pharma Ltd. is a combination medication containing Aceclofenac, Paracetamol, and Serratiopeptidase. It is primarily used to relieve pain, reduce inflammation, and decrease swelling associated with various musculoskeletal and inflammatory conditions.

Here are some frequently asked questions about FLOZEN AA TAB:

What is FLOZEN AA TAB used for?

FLOZEN AA TAB is used for short-term relief from pain, inflammation, and swelling in various conditions affecting joints and muscles. This includes conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, sprains, strains, dental pain, and post-operative pain. It also helps in the resolution of oedema (swollen tissue with fluid).

How does FLOZEN AA TAB work?

FLOZEN AA TAB works through its three active ingredients:

• Aceclofenac: This is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the action of an enzyme called cyclo-oxygenase (COX), which is responsible for producing prostaglandins that cause pain and swelling.
• Paracetamol (Acetaminophen): This acts as an analgesic (pain reducer) and antipyretic (fever reducer). It enhances the pain-relief action of aceclofenac and works by affecting pain centers in the brain and reducing fever.
• Serratiopeptidase: This is an enzyme that helps reduce swelling and promotes healing by breaking down abnormal proteins, like fibrin, at the site of inflammation. It causes thinning of fluids around the injury site, facilitating smoother fluid drainage in swollen tissue.

What is the usual dosage of FLOZEN AA TAB?

The dosage of FLOZEN AA TAB will be determined by your doctor based on your medical condition. It is typically taken orally, usually with or after food, to minimize stomach upset. The tablet should be swallowed whole with a glass of water and not crushed, broken, or chewed. A common recommended dose is one tablet in the morning and one in the evening, with a maximum recommended dose of two tablets daily.

What are the possible side effects of FLOZEN AA TAB?

Common side effects may include nausea, vomiting, stomach pain, indigestion, loss of appetite, diarrhea, stomach upset, and dizziness. In rare cases, more serious side effects such as liver or kidney problems may occur, especially with prolonged use. If side effects are persistent or severe, consult your doctor.

Is FLOZEN AA TAB safe during pregnancy or breastfeeding?

FLOZEN AA TAB is generally not recommended for use during pregnancy, especially during the last trimester, unless specifically advised by a doctor due to compelling reasons. It is also not advised for breastfeeding women, as some components may pass into breast milk in very low concentrations, and NSAIDs should ideally be avoided while breastfeeding.

Can FLOZEN AA TAB be taken with other medications?

FLOZEN AA TAB can interact with certain medications. You should avoid taking it with other painkillers, especially those containing nimesulide, oxyphenbutazone, metamizole, or other NSAIDs (including aspirin and COX-2 selective inhibitors), as this can increase the risk of adverse effects. It can also interact with blood-thinning agents like warfarin, increasing the risk of bleeding. Inform your doctor about all medications you are currently taking to avoid potential interactions.

What precautions should be taken with FLOZEN AA TAB?

• Avoid consuming alcohol while taking this medicine as it may increase the risk of liver damage.
• Inform your doctor if you have a history of peptic ulcers, gastric bleeding, severe heart failure, high blood pressure, liver disease, or kidney disease, as the medicine may be contraindicated or require dose adjustments.
• Caution is advised in patients with bronchial asthma, as NSAIDs can precipitate bronchospasm.
• It may cause dizziness or drowsiness, so avoid driving or operating machinery until you know how the medicine affects you.
• Do not exceed the recommended dose or duration of treatment.

What happens if a dose is missed?

If you miss a dose of FLOZEN AA TAB, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should FLOZEN AA TAB be stored?

FLOZEN AA TAB should be stored in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. Always follow the storage instructions provided on the medication's packaging.