Veloz L Capsule

VELOZ L CAPSULE

VELOZ L CAPSULE, manufactured by Torrent Pharmaceuticals Ltd, is a combination medication designed for comprehensive management of various gastrointestinal conditions.

Composition

Each capsule contains a dual-action formula:

• Rabeprazole (20 mg): A proton pump inhibitor (PPI) that effectively reduces the production of excessive stomach acid by blocking the H+/K+-ATPase enzyme system in the stomach's parietal cells.
• Levosulpiride (75 mg): A prokinetic agent and selective dopamine D2-receptor antagonist that enhances gastrointestinal motility, increases lower esophageal sphincter pressure, and accelerates gastric emptying, thereby preventing acid reflux and improving symptoms like bloating and delayed gastric emptying.

Uses

VELOZ L CAPSULE is prescribed for the treatment of a range of acidity-related conditions and gastrointestinal motility disorders, including:

• Gastroesophageal Reflux Disease (GERD), providing relief from acid reflux and heartburn.
• Peptic and Duodenal Ulcers, promoting healing by protecting the stomach lining and reducing acid production.
• Zollinger-Ellison Syndrome, which involves excessive acid production due to tumors.
• Irritable Bowel Syndrome (IBS), particularly in cases with bloating and delayed gastric emptying.
• Functional Dyspepsia, alleviating symptoms like early satiety, nausea, and abdominal discomfort.
• Management of nausea and vomiting.
• Helicobacter pylori infection (as part of a multi-drug regimen).

Dosage and Administration

VELOZ L CAPSULE is typically taken once daily, preferably in the morning, about one hour before a meal. The capsule should be swallowed whole with a glass of water and should not be chewed, crushed, or broken. The duration of treatment depends on the severity of the condition and the patient's response to the medication, as advised by a healthcare professional.

Side Effects

Common side effects may include:

• Headache, dizziness, and drowsiness.
• Nausea, vomiting, diarrhea, constipation, gas, and abdominal pain.
• Weakness and flu-like symptoms.
• Rash and itching.

More serious, though less common, side effects can include breast tenderness or enlargement in males, menstrual changes, and unusual production of breast milk in women and men. Prolonged use may increase the risk of osteoporosis (weak and brittle bones) and hypomagnesemia (low magnesium levels).

Precautions

• Allergies: Do not take if allergic to Rabeprazole, Levosulpiride, or any other components of the capsule.
• Medical History: Inform your doctor if you have a history of pheochromocytoma, epilepsy, mania, gastrointestinal bleeding, intestinal obstruction, severe kidney or liver impairment, brain tumor, or heart disease.
• Pregnancy and Breastfeeding: Not recommended during pregnancy or breastfeeding unless deemed essential by a doctor.
• Alcohol: Avoid alcohol consumption as it can worsen drowsiness and stomach irritation.
• Driving: May cause dizziness and drowsiness; caution is advised when driving or operating machinery.
• Drug Interactions: May interact with antipsychotics, other gastroprokinetics, dopamine precursors (e.g., Levodopa), antifungals (e.g., Ketoconazole, Itraconazole), Atazanavir, sucralfate, antihypertensive medicines, Methotrexate, Tacrolimus, and Warfarin.

Storage

Store VELOZ L CAPSULE in a cool and dry place, away from direct sunlight, at a temperature below 30°C (20-25°C). Keep it out of reach and sight of children.

Frequently Asked Questions (FAQs) about VELOZ L CAPSULE

VELOZ L CAPSULE by TORRENT PHARMACEUTICALS LTD is a prescription medicine containing Rabeprazole and Levosulpiride, commonly used for various gastric issues.

What is VELOZ L CAPSULE used for?

VELOZ L CAPSULE is primarily used to manage and provide relief from various gastric conditions. These include Gastroesophageal Reflux Disease (GERD), peptic ulcers (gastric and duodenal ulcers), Zollinger-Ellison syndrome, acidity, heartburn, functional dyspepsia, irritable bowel syndrome, and diabetic gastroparesis. It can also help in managing nausea, vomiting, and vertigo or dizziness associated with certain conditions.

How does VELOZ L CAPSULE work?

VELOZ L CAPSULE contains two active ingredients: Rabeprazole and Levosulpiride. Rabeprazole is a proton pump inhibitor (PPI) that reduces the production of stomach acid by blocking the H+/K+-ATPase enzyme system in the stomach's parietal cells. Levosulpiride is a prokinetic agent that increases the movement of the stomach and intestines, speeding up gastric emptying and increasing the pressure of the lower esophageal sphincter, which helps prevent the backflow of food and acid into the esophagus. This dual action effectively manages acid-related symptoms and improves digestive function.

What is the usual dosage for VELOZ L CAPSULE?

VELOZ L CAPSULE is typically taken once daily, preferably in the morning, before a meal. The capsule should be swallowed whole with a glass of water and should not be crushed, chewed, or broken. Your doctor will determine the exact dosage and duration of treatment based on your specific condition and how you respond to the medication.

What are the possible side effects of VELOZ L CAPSULE?

Common side effects of VELOZ L CAPSULE may include nausea, vomiting, stomach pain, abdominal pain, diarrhea, flatulence, headache, dizziness, constipation, weakness, fatigue, and flu-like symptoms. If any of these side effects persist or worsen, it is important to consult your doctor. Long-term use may increase the risk of certain side effects such as bone fractures, vitamin B12 deficiency, and low magnesium levels (hypomagnesemia).

Is VELOZ L CAPSULE safe during pregnancy or breastfeeding?

VELOZ L CAPSULE is generally not recommended for use during pregnancy and is considered contraindicated for breastfeeding women. If you are pregnant, planning pregnancy, or breastfeeding, it is crucial to consult your doctor to discuss the potential risks and benefits and explore alternative options.

Can VELOZ L CAPSULE be taken with other medications?

It is important to inform your doctor about all medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins, as they may interact with VELOZ L CAPSULE. Certain medications, such as antacids, should be taken at least 2 hours before or after VELOZ L CAPSULE to avoid interference with its absorption. Other medications that may interact include antifungal medicines (e.g., Ketoconazole, Itraconazole), HIV medications (e.g., Atazanavir), blood thinners (e.g., Warfarin), anti-cancer drugs (e.g., Methotrexate), immunosuppressants (e.g., Tacrolimus, Mycophenolate mofetil), certain antibiotics (e.g., Amoxicillin, Clarithromycin), and Levodopa (used for Parkinson's disease).

What precautions should be taken while using VELOZ L CAPSULE?

You should avoid or limit alcohol consumption while taking VELOZ L CAPSULE, as it can worsen side effects like drowsiness, dizziness, and confusion, and may increase the risk of stomach irritation. This medication may cause dizziness and drowsiness, so caution is advised when driving or operating machinery until you know how it affects you. Inform your doctor if you have a history of liver or kidney problems, as dose adjustments or extra precautions may be necessary. VELOZ L CAPSULE is not recommended for children and adolescents under 18 years of age.

What happens if a dose of VELOZ L CAPSULE is missed?

If you miss a dose of VELOZ L CAPSULE, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should VELOZ L CAPSULE be stored?

VELOZ L CAPSULE should be stored below 30°C, in a cool and dry place. It should be protected from light and moisture and kept out of the reach and sight of children.