Paxidep Cr 12.5 Mg Tablet (10 Tab)

PAXIDEP CR 12.5 MG TABLET

PAXIDEP CR 12.5 MG TABLET is an antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) class of medicines, manufactured by Sun Pharma Laboratories Ltd..

Composition

The active ingredient in PAXIDEP CR 12.5 MG TABLET is Paroxetine at a strength of 12.5 mg. Paroxetine works by inhibiting the reuptake of serotonin in the brain, thereby increasing serotonin concentrations and regulating mood.

Uses

PAXIDEP CR 12.5 MG TABLET is primarily prescribed for the management of various mental health conditions, including:

• Major depressive disorder.
• Obsessive-compulsive disorder (OCD).
• Panic disorder.
• Social anxiety disorder.
• Post-traumatic stress disorder (PTSD).
• Generalized anxiety disorder (GAD).
• Premenstrual dysphoric disorder.

Dosage and Administration

This medicine can be taken with or without food, preferably in the morning to help reduce stomach upset. The typical starting dose for adults is usually 12.5 mg once daily, but the doctor may adjust the dosage based on the patient's medical condition, often in increments of 12.5 mg/day at intervals of at least one week. It is crucial not to suddenly stop or change the dose without consulting a doctor, as this can lead to withdrawal symptoms. For elderly or debilitated patients or those with severe renal or hepatic impairment, the initial dose may be 12.5 mg/day, not exceeding 50 mg/day.

Side Effects

Common side effects may include:

• Nausea, diarrhea, constipation, vomiting.
• Dizziness, headache, fatigue, insomnia, drowsiness, confusion.
• Dry mouth, loss of appetite, increased sweating, tremors.
• Sexual side effects like decreased sexual drive, delayed ejaculation, and erectile dysfunction.
• Abnormal dreams.

Serious side effects, though rare, can include unusual bruising or bleeding, difficult urination, seizures, restlessness (akathisia), or signs of low sodium. Patients should contact their doctor immediately if these or any other severe symptoms occur.

Precautions

• Pregnancy and Breastfeeding: It is not recommended during pregnancy as it may harm the fetus. Consult a doctor if pregnant, planning pregnancy, or breastfeeding, as it may pass into breast milk.
• Alcohol: Avoid alcohol consumption as it can worsen side effects like dizziness and drowsiness.
• Driving and Operating Machinery: This medicine may cause dizziness, confusion, sleepiness, and blurred vision, so avoid driving or operating machinery until you know how it affects you.
• Pre-existing Conditions: Inform the doctor about any history of epilepsy, diabetes, liver or kidney problems, heart disease, or glaucoma.
• Children and Adolescents: Not recommended for individuals under 18 years of age due to increased risk of side effects such as suicidal thoughts and aggression.
• Drug Interactions: Inform your doctor about all current medications, especially MAOIs (Monoamine Oxidase Inhibitors) like phenelzine, linezolid, thioridazine, or pimozide, as concomitant use is contraindicated or requires caution due to potential serious interactions such as serotonin syndrome.

Storage

Store PAXIDEP CR 12.5 MG TABLET in a cool, dry place, away from direct sunlight and moisture, at room temperature (10ºC to 25ºC or below 30ºC). Keep out of reach and sight of children.

PAXIDEP CR 12.5 MG TABLET, containing Paroxetine, is an antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) class. It is prescribed for various mood and anxiety disorders. Here are some frequently asked questions about this medicine:

What is PAXIDEP CR 12.5 MG TABLET used for?

PAXIDEP CR 12.5 MG TABLET is primarily used to treat major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and generalised anxiety disorder.

How does PAXIDEP CR 12.5 MG TABLET work?

This medicine contains Paroxetine, a selective serotonin reuptake inhibitor (SSRI). It works by blocking the reabsorption of serotonin, a natural chemical messenger in the brain that helps regulate mood. By increasing the levels of serotonin in the nerve synapses, PAXIDEP CR 12.5 MG TABLET helps to improve mood and alleviate symptoms of depression and anxiety disorders.

What is the usual dosage for PAXIDEP CR 12.5 MG TABLET?

PAXIDEP CR 12.5 MG TABLET is typically taken once daily, usually in the morning, with or without food. Taking it with food may help reduce stomach upset. Your doctor will determine the appropriate dose and frequency based on your medical condition, often starting with a lower dose and gradually increasing it. It is crucial to follow your doctor's prescribed dosage and not to alter it or stop the medication without consulting them.

What are the possible side effects of PAXIDEP CR 12.5 MG TABLET?

Common side effects may include insomnia (difficulty sleeping), dizziness, headache, nausea, diarrhoea, fatigue, dry mouth, loss of appetite, increased sweating, nervousness, tremors, confusion, constipation, and yawning. Sexual side effects such as decreased sexual drive, delayed ejaculation, and erectile dysfunction may also occur. If you experience a sudden worsening of mood, thoughts of harming yourself, unusual bleeding or bruising, seizures, severe restlessness (akathisia), or symptoms of low sodium (tiredness, weakness, confusion, muscle aches), contact your doctor immediately. A serious condition called serotonin syndrome (symptoms include confusion, hallucinations, increased heart rate, fever, sweating, shivering, muscle rigidity, and extreme changes in blood pressure) can also occur.

Is PAXIDEP CR 12.5 MG TABLET safe during pregnancy or breastfeeding?

Pregnancy: PAXIDEP CR 12.5 MG TABLET is generally not recommended during pregnancy as it may cause harm to the fetus. Some studies suggest a small risk of affecting a baby's heart development and may cause short-term withdrawal symptoms or breathing problems in the baby if taken close to delivery. It may also slightly increase the risk of bleeding after delivery. Always consult your doctor to discuss the risks and benefits if you are pregnant or planning a pregnancy.

Breastfeeding: It is probably unsafe or should be used with caution during breastfeeding. The medicine can pass into breast milk, and limited data suggests it may harm the baby. While some sources indicate it passes in very small amounts and may be acceptable if the baby is healthy, it is essential to consult your doctor. Monitor your baby for unusual sleepiness, irritability, or feeding issues.

Can PAXIDEP CR 12.5 MG TABLET be taken with other medications?

PAXIDEP CR 12.5 MG TABLET should not be taken with monoamine oxidase inhibitors (MAOIs) like phenelzine, isocarboxazid, linezolid, or procarbazine, due to a significant risk of serotonin syndrome. It is also not recommended with Thioridazine or Pimozide. Caution is advised when taking it with other antidepressants or St. John's wort. If you are diabetic, PAXIDEP CR 12.5 MG TABLET may alter your blood sugar levels, requiring careful monitoring and potential adjustment of your diabetes medication. It may also reduce the effectiveness of Tamoxifen. Always inform your doctor about all other medications you are taking to avoid potential drug interactions.

What precautions should be taken while on PAXIDEP CR 12.5 MG TABLET?

Do not stop taking PAXIDEP CR 12.5 MG TABLET suddenly, as abrupt discontinuation can lead to unpleasant withdrawal symptoms like dizziness, nausea, headaches, and sleep disturbances. Avoid consuming alcohol while taking this medicine, as it can worsen side effects such as drowsiness and dizziness. Exercise caution when driving or operating heavy machinery, especially if you experience dizziness, confusion, sleepiness, or blurred vision. This medicine is generally not recommended for children and adolescents under 18 years of age due to safety and effectiveness concerns, including an increased risk of suicidal thoughts. Inform your doctor if you have pre-existing conditions such as kidney, liver, or heart problems, epilepsy, diabetes, glaucoma, or low sodium levels.

What happens if a dose of PAXIDEP CR 12.5 MG TABLET is missed?

If you forget to take a dose, take it as soon as you remember, provided it is before you go to bed on the same day. If you only remember the next day, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten one. Missing doses can lead to withdrawal symptoms or a return of your original symptoms.

How should PAXIDEP CR 12.5 MG TABLET be stored?

PAXIDEP CR 12.5 MG TABLET should be stored in a cool, dry place, away from direct sunlight and moisture. It is best kept at room temperature, typically between 10ºC to 25ºC or below 30ºC. Keep the medicine out of the reach and sight of children.