Volix Trio 2 Mg Tablet (15 Tab)

VOLIX TRIO 2 MG TABLET

VOLIX TRIO 2 MG TABLET, manufactured by Sun Pharmaceutical Industries Ltd., is an oral anti-diabetic medication used for the management of Type 2 Diabetes Mellitus.

Composition

Each tablet contains a combination of three active ingredients:

• Glimepiride: 2 mg
• Metformin: 500 mg
• Voglibose: 0.2 mg

Glimepiride stimulates insulin release from the pancreas, Metformin reduces glucose production in the liver and improves insulin sensitivity, and Voglibose slows down carbohydrate absorption from the intestines.

Uses

VOLIX TRIO 2 MG TABLET is primarily used for the treatment of Type 2 Diabetes Mellitus in adults. It helps to control high blood sugar levels when diet, exercise, and other initial treatments are not sufficient.

Dosage and Administration

This medicine should be taken orally as directed by a doctor. It is generally advised to take the tablet with or immediately before meals. The tablet should be swallowed whole with water and not crushed or chewed. Regular monitoring of blood sugar levels is important to determine the appropriate dosage.

Side Effects

Common side effects may include:

• Hypoglycemia (low blood sugar levels), characterized by sweating, dizziness, and shaking
• Gastrointestinal symptoms such as nausea, vomiting, diarrhea, stomach pain, and flatulence
• Headache
• Taste changes
• Upper respiratory tract infection

Serious but rare side effects can include severe hypoglycemia, lactic acidosis, and hypersensitivity reactions. Long-term use may also lead to Vitamin B12 deficiency.

Precautions

• Contraindications: Not recommended for patients with Type 1 Diabetes Mellitus, diabetic ketoacidosis, severe kidney disease, or severe liver disease.
• Pregnancy and Breastfeeding: Not generally recommended during pregnancy or breastfeeding.
• Alcohol: Avoid alcohol consumption as it can increase the risk of low blood sugar and lactic acidosis.
• Interactions: Inform your doctor about all other medications, including oral contraceptives, water pills, rifampicin, phenytoin, and blood thinners, as they may interact with VOLIX TRIO 2 MG TABLET.
• Other: Monitor blood sugar levels regularly. Do not stop the medication abruptly without consulting a doctor.

Storage

Store VOLIX TRIO 2 MG TABLET in a cool, dry place, below 30°C, and protect it from direct light and moisture. Keep it out of reach and sight of children.

What is Volix Trio 2 MG Tablet used for?

Volix Trio 2 MG Tablet is primarily used to manage Type 2 Diabetes Mellitus in adults. It is prescribed when diet, exercise, and other single or dual therapy treatments are not sufficient to adequately control blood sugar levels. This medication helps in controlling high blood sugar levels and reducing postprandial (after-meal) glucose spikes.

How does Volix Trio 2 MG Tablet work?

Volix Trio 2 MG Tablet is a combination of three active ingredients: Glimepiride, Metformin, and Voglibose, each working through a different mechanism to help control blood sugar.

• Glimepiride: Stimulates the pancreas to release more insulin, which helps lower blood glucose levels.
• Metformin: Reduces the production of glucose in the liver, delays the absorption of glucose from the intestines, and improves the body's sensitivity to insulin.
• Voglibose: Slows down the breakdown of complex carbohydrates into simpler sugars in the intestine, thereby delaying their absorption into the bloodstream and preventing sharp rises in blood sugar after meals.

What is the usual dosage for Volix Trio 2 MG Tablet?

The dosage of Volix Trio 2 MG Tablet is determined by your doctor based on your individual condition and response to treatment. It is generally recommended to take this tablet with or immediately before meals, at the same time each day, as advised by your doctor. The tablet should be swallowed whole with a glass of water and not chewed, crushed, or broken. Do not increase your dosage without consulting your doctor.

What are the possible side effects of Volix Trio 2 MG Tablet?

Common side effects can include low blood sugar (hypoglycemia), nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, headache, dizziness, and flatulence. Less common side effects may include taste changes, blurred vision, and weight gain. Rarely, more serious side effects like lactic acidosis or severe hypoglycemia can occur, which require immediate medical attention.

Is Volix Trio 2 MG Tablet safe during pregnancy or breastfeeding?

Volix Trio 2 MG Tablet is generally not recommended during pregnancy as it may be unsafe and could harm the developing fetus. Similarly, it is not recommended for use while breastfeeding, as the medication may pass into breast milk and potentially harm the nursing infant. Always consult your doctor for alternative options if you are pregnant, planning a pregnancy, or breastfeeding.

Can Volix Trio 2 MG Tablet be taken with other medications?

Volix Trio 2 MG Tablet can interact with other medications, so it is crucial to inform your doctor about all prescribed and non-prescribed medicines, herbal supplements, and treatments you are currently taking. Some known interactions include those with anticoagulants (e.g., warfarin), NSAIDs (e.g., ibuprofen), beta-blockers (e.g., atenolol), diuretics (e.g., hydrochlorothiazide), ACE inhibitors (e.g., enalapril), oral contraceptives, rifampicin, phenytoin, and thyroid disorder medications.

What precautions should be taken while using Volix Trio 2 MG Tablet?

Several precautions should be observed:

• Alcohol Consumption: Avoid consuming alcohol, as it can increase the risk of low blood sugar (hypoglycemia) and a rare but serious side effect called lactic acidosis.
• Medical Conditions: This medicine is contraindicated in patients with severe kidney or liver disease, Type 1 diabetes mellitus, diabetic ketoacidosis, or metabolic acidosis. Caution is advised for patients with heart conditions.
• Monitoring: Regular monitoring of blood sugar levels, kidney function, and liver function is important during treatment.
• Hypoglycemia: Be aware of the signs of low blood sugar (sweating, dizziness, headache, shaking) and always carry a fast-acting source of glucose, such as sugary food or fruit juice.
• Other: Inform your doctor if you are scheduled for a CT scan or MRI with contrast media, or if you experience severe diarrhea, vomiting, or dehydration. Avoid grapefruit juice, as it may interact with the medication. Your ability to drive may be affected by fluctuations in blood sugar.

What happens if a dose of Volix Trio 2 MG Tablet is missed?

If you miss a dose of Volix Trio 2 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should Volix Trio 2 MG Tablet be stored?

Volix Trio 2 MG Tablet should be stored in a cool, dry place, protected from direct light and moisture. Keep the medicine out of the reach and sight of children and pets. Always ensure to use the product before its expiry date.