Azmarda 50 Mg Tab

AZMARDA 50 MG TABLET

AZMARDA 50 MG Tablet, manufactured by J B Chemicals and Pharmaceuticals Ltd, is a medication prescribed for the management of chronic heart failure.

• Composition: Each tablet contains Sacubitril (24mg) and Valsartan (26mg). This combination belongs to a class of drugs known as Angiotensin Receptor Neprilysin Inhibitors (ARNI).

• Uses: AZMARDA 50 MG Tablet is used to treat chronic heart failure in adults, particularly those with reduced ejection fraction (New York Heart Association Class II-IV). It works by relaxing blood vessels and easing the heart's workload, thereby reducing the risk of cardiovascular death and hospitalization, and improving symptoms like breathlessness, swelling, and fatigue.

• Dosage and Administration: Take AZMARDA 50 MG Tablet as prescribed by your doctor. The typical dosage involves taking one tablet daily, preferably at the same time each day, with or without food. Do not chew, crush, or break the tablet. It is crucial not to stop the medication without consulting your doctor, even if you feel well. A starting dose of 50 mg twice daily may be recommended for certain patients, with a target dose of 200 mg twice daily.

• Side Effects:

  • Common: Dizziness, light-headedness (hypotension), cough, headache, tiredness, nausea, diarrhea, weakness, increased potassium levels (hyperkalemia), and impaired renal function.
  • Serious: Rarely, angioedema (swelling of the face, lips, tongue, or throat) can occur.

• Precautions:

  • AZMARDA 50 MG Tablet is not recommended during pregnancy (especially after the first 3 months) or while breastfeeding.
  • It should be used with caution in patients with kidney or liver disease, and those with pre-existing low blood pressure or high potassium levels.
  • Regular monitoring of blood pressure and kidney function is advised during treatment.
  • Avoid alcohol consumption as it may increase dizziness.
  • Inform your doctor about all other medications you are taking, including ACE inhibitors, ARBs, diuretics, NSAIDs, and aliskiren, as interactions can occur.
  • If you experience dizziness, avoid driving or operating machinery.
  • Contraindicated in patients with a history of angioedema related to ACE inhibitor or ARB use.

• Storage: Store the tablets at room temperature, typically below 30°C (or 20-25°C), away from direct light and moisture, in their original packaging. Keep out of sight and reach of children and pets.

Here are frequently asked questions about AZMARDA 50 MG TAB, along with their concise answers:

What is AZMARDA 50 MG TAB used for?

AZMARDA 50 MG TAB is primarily used to treat chronic heart failure in adults, a condition where the heart cannot pump blood efficiently. It helps to reduce the risk of hospitalization, lower cardiovascular death rates, and improve survival. It also helps alleviate symptoms such as breathlessness, swelling, and fatigue, improving the patient's quality of life.

How does AZMARDA 50 MG TAB work?

AZMARDA 50 MG TAB is a combination medicine containing sacubitril and valsartan. Sacubitril works by inhibiting an enzyme called neprilysin, which increases the levels of natural substances in the body that reduce fluid retention and promote blood vessel relaxation. Valsartan, an angiotensin II receptor blocker, works by blocking a hormone that causes blood vessels to narrow. Together, these actions relax and widen blood vessels, making it easier for the heart to pump blood, reducing blood pressure, and improving overall heart function.

What is the usual dosage for AZMARDA 50 MG TAB?

The usual daily dosage for AZMARDA 50 MG TAB is one tablet, taken at the same time every day, as prescribed by your doctor. It can be taken with or without food. It is important to swallow the tablet whole with water and not to exceed the suggested dose without consulting your doctor, as the exact dosage may vary based on your condition and response to treatment.

What are the possible side effects of AZMARDA 50 MG TAB?

Common side effects may include dizziness, light-headedness (due to low blood pressure), cough, headache, tiredness, nausea, weakness, and increased potassium levels in the blood (hyperkalemia). Some individuals might also experience impaired renal function or diarrhea. If any side effects worsen or persist, it is important to consult your doctor.

Is AZMARDA 50 MG TAB safe during pregnancy or breastfeeding?

No, AZMARDA 50 MG TAB is not recommended during pregnancy and is considered unsafe, especially after the first three months, as it can cause serious harm to the developing baby. It is also not recommended for use by breastfeeding mothers. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can AZMARDA 50 MG TAB be taken with other medications?

AZMARDA 50 MG TAB can interact with other medications. It should not be taken with ACE inhibitors (e.g., enalapril, ramipril, lisinopril); a gap of at least 36 hours is required before or after taking an ACE inhibitor. It is also contraindicated if you have diabetes or impaired kidney function and are taking aliskiren. Caution is advised with other blood pressure medications, diuretics, NSAIDs, anticoagulants, potassium supplements, and sildenafil. Always inform your doctor about all prescription, over-the-counter medications, and herbal supplements you are taking.

What precautions should be taken while on AZMARDA 50 MG TAB?

Avoid consuming alcohol as it can increase the risk of dizziness. Since this medicine can cause dizziness or fatigue, it is advisable to avoid driving or operating heavy machinery if you experience these side effects. Patients with kidney or liver disease should use this medicine with caution, and dose adjustments may be necessary. Regular monitoring of blood pressure and kidney function is recommended. It is also important to avoid high-potassium foods or supplements unless advised by your doctor.

What happens if a dose of AZMARDA 50 MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should AZMARDA 50 MG TAB be stored?

Store AZMARDA 50 MG TAB in a cool, dry place, protected from light and moisture, ideally in its original packaging. Keep the medicine out of the reach and sight of children and pets. Ensure it is used before the expiry date mentioned on the packaging.