Stalix Dm 10/100/500 Mg Tablet (10 Tab)

STALIX DM 10/100/500 MG TABLET

STALIX DM 10/100/500 MG TABLET is a prescription medicine manufactured by Torrent Pharmaceuticals Ltd., designed for the comprehensive management of type 2 diabetes mellitus.

• Composition: Each tablet contains a combination of three active ingredients:

  • Dapagliflozin: 10 mg
  • Sitagliptin: 100 mg
  • Metformin: 500 mg

• Uses: This medication is primarily used to improve blood sugar control in adults with type 2 diabetes mellitus when diet, exercise, and therapy with conventional medicines do not result in an adequate response. It aids in better glycemic control, improves insulin sensitivity, and helps reduce the risk of diabetes-related complications such as kidney damage and cardiovascular disease.

• Dosage and Administration: STALIX DM tablets should be taken orally as advised by your doctor. The tablet should be swallowed whole with water, without crushing or chewing. It can be taken with or without food, preferably at the same time each day to maintain consistency. Do not alter the prescribed dose or stop the medication without consulting your doctor.

• Side Effects: Common side effects may include genital mycotic infections, nasopharyngitis (common cold symptoms), urinary tract infections, diarrhea, headache, nausea, and vomiting. More serious, though rare, side effects can include lactic acidosis or kidney problems. Consult your doctor if any side effects persist or worsen.

• Precautions:

  • Pregnancy and Breastfeeding: Not recommended for use during pregnancy or in breastfeeding women. Consult your doctor.
  • Kidney/Liver Disease: Use with caution in patients with kidney or liver impairment. Regular monitoring of kidney function is advisable.
  • Alcohol: Avoid excessive alcohol intake as it can interact with the medication, increasing the risk of hypoglycemia and lactic acidosis.
  • Interactions: Inform your doctor about all other medications, supplements, and herbal products you are taking, as some medicines (e.g., insulin, sulphonylureas, diuretics, carbonic anhydrase inhibitors) can interact with STALIX DM.

• Storage: Store the medicine in a tightly sealed container at room temperature, ideally below 30°C. Protect it from moisture and direct sunlight, and keep it out of reach of children.

Here are the most frequently asked questions about STALIX DM 10/100/500 MG Tablet, along with concise answers:

What is STALIX DM 10/100/500 MG Tablet used for?

STALIX DM 10/100/500 MG Tablet is primarily prescribed for the management of Type 2 Diabetes Mellitus in adults. It helps improve blood sugar control, especially when diet and exercise alone are not sufficient. This medicine is also beneficial in enhancing blood sugar control when metformin therapy alone, or dual therapy with metformin plus either dapagliflozin or sitagliptin, is not enough. Additionally, it may help lower the risk of heart failure and diabetic kidney disease by improving vascular function, reducing albuminuria, and supporting healthy blood pressure levels.

How does STALIX DM 10/100/500 MG Tablet work?

STALIX DM 10/100/500 MG Tablet is a combination of three active ingredients: Dapagliflozin, Sitagliptin, and Metformin, each working through different mechanisms to control blood sugar levels.

• Dapagliflozin (10 mg): This acts as a sodium-glucose co-transporter 2 (SGLT2) inhibitor. It reduces the re-absorption of glucose in the kidneys, leading to more glucose being removed from the body through urine, thereby lowering blood sugar levels.
• Sitagliptin (100 mg): This is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by increasing the levels of certain natural substances (incretins) in the body that help the pancreas release more insulin when blood sugar is high and decrease the amount of glucose produced by the liver.
• Metformin (500 mg): As a biguanide, metformin helps reduce the amount of glucose produced by the liver. It also increases the sensitivity of muscle cells to insulin, helping the body use glucose more effectively and delaying sugar absorption from the intestines.

What is the usual dosage of STALIX DM 10/100/500 MG Tablet?

The daily dosage of STALIX DM 10/100/500 MG Tablet is determined by your doctor, based on factors such as the severity of your condition, your blood sugar levels, and your response to the medicine. It is typically taken once or twice daily with meals to minimize gastrointestinal side effects. The tablet should be swallowed whole with a glass of water, and you should not crush, chew, or break it, as this can affect its effectiveness. Always adhere strictly to the prescribed dose and do not alter or stop the medication without consulting your doctor.

What are the possible side effects of STALIX DM 10/100/500 MG Tablet?

Common side effects of STALIX DM 10/100/500 MG Tablet may include genital mycotic (fungal) infections, nasopharyngitis (common cold symptoms like runny nose, sore throat, sneezing), urinary tract infections, diarrhea, nausea, headache, and vomiting. In rare cases, more serious side effects can occur, such as lactic acidosis (a buildup of lactic acid in the blood), ketoacidosis, pancreatitis, or kidney problems. If you experience any severe or persistent side effects, contact your doctor immediately.

Is STALIX DM 10/100/500 MG Tablet safe during pregnancy or breastfeeding?

Caution is advised when taking STALIX DM 10/100/500 MG Tablet if you are pregnant or planning to become pregnant, as there is limited information on its effect during pregnancy. Similarly, breastfeeding women should exercise caution, and the medicine is generally not recommended as it is not known if it passes into human breast milk. It is crucial to inform your doctor if you are pregnant or breastfeeding before starting this medication.

Can STALIX DM 10/100/500 MG Tablet be taken with other medications?

STALIX DM 10/100/500 MG Tablet can interact with certain other medicines. For example, when used with insulin or sulfonylureas, it may increase the risk of low blood sugar (hypoglycemia). Medicines like carbonic anhydrase inhibitors (e.g., acetazolamide, topiramate) and certain diuretics (water pills) can increase the risk of lactic acidosis. Cationic medications such as amiloride, digoxin, morphine, procainamide, quinidine, and vancomycin may reduce metformin elimination. Always inform your doctor about all prescription, non-prescription, and herbal supplements you are currently taking to prevent unwanted interactions.

What precautions should be taken while taking STALIX DM 10/100/500 MG Tablet?

Several precautions should be observed:

• Kidney and Liver Conditions: Use with caution if you have kidney or liver problems. This medication is not recommended for individuals with severe renal impairment or severe liver disease, as it could worsen their condition or increase the risk of lactic acidosis.
• Alcohol Consumption: Avoid excessive alcohol intake while on this medication, as it can interfere with its effectiveness, lower blood sugar levels, and increase the risk of lactic acidosis.
• Hydration: Stay well-hydrated while taking this medication to help prevent kidney problems.
• Allergies: Do not take STALIX DM 10/100/500 MG Tablet if you are allergic to dapagliflozin, metformin, sitagliptin, or any other ingredients.
• Other Conditions: It is not recommended for Type 1 diabetes, diabetic ketoacidosis, respiratory failure, heart failure, or severe infection.
• Monitoring: Regular monitoring of blood sugar levels and kidney function is essential while on this medication.

What happens if a dose of STALIX DM 10/100/500 MG Tablet is missed?

If you miss a dose of STALIX DM 10/100/500 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this may cause your blood sugar level to fall too rapidly or increase the risk of side effects.

How should STALIX DM 10/100/500 MG Tablet be stored?

Store STALIX DM 10/100/500 MG Tablet at room temperature, ideally below 30°C (86°F). Protect the medicine from moisture and light, keeping it in its original packaging until use. Ensure it is stored safely out of reach of children and pets. Always check the expiry date before taking your medicine.