Nobel Mr Tab

NOBEL MR TAB

NOBEL MR TAB, manufactured by Mankind Pharma Ltd, is a combination medicine designed to provide relief from pain, inflammation, and muscle spasms.

• Composition Each tablet of NOBEL MR contains a blend of three active ingredients:

  • Nimesulide: 100 mg
  • Paracetamol: 325 mg
  • Tizanidine: 2 mg

  Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation. Paracetamol acts as an analgesic (pain reliever) and antipyretic (fever reducer). Tizanidine is a muscle relaxant that works on the brain and spinal cord to alleviate muscle stiffness and improve muscle movement.

• Uses NOBEL MR TAB is prescribed for a variety of conditions involving pain and muscle spasms, including:

  • Musculoskeletal pain and inflammation
  • Muscle pain and spasms
  • Osteoarthritis
  • Tooth pain
  • Bone and joint pain
  • Headache and migraine
  • Period pain (dysmenorrhea)
  • Rheumatic pain and backache
  • Fever associated with muscular pain

• Dosage and Administration Take NOBEL MR TAB orally with or without food, as advised by your doctor. It should be swallowed whole with water and not crushed, chewed, or broken. Do not exceed the recommended dosage, and follow the duration of treatment prescribed by your doctor. Taking it with food can help prevent an upset stomach.

• Side Effects Common side effects may include:

  • Nausea, vomiting, diarrhea
  • Dizziness, drowsiness, sleepiness
  • Dry mouth
  • Stomach discomfort or upset
  • Weakness
  • Increased liver enzymes
  • Skin rash

  Serious side effects, though rare, warrant immediate medical attention:

  • Persistent nausea and vomiting
  • Yellowing of the skin or eyes (jaundice, indicating possible liver problems)
  • Severe abdominal pain
  • Black or bloody stools
  • Difficulty breathing, chest pain
  • Unusual muscle weakness

• Precautions

  • Pregnancy and Breastfeeding: Not recommended during pregnancy, especially in the first and third trimesters, due to potential risks to the developing baby. Avoid during breastfeeding as safety in infants is not established. Consult a doctor for alternative options.
  • Alcohol: Avoid or limit alcohol consumption as it can increase the risk of stomach problems, liver injury, and dizziness.
  • Driving: May cause dizziness and drowsiness; avoid activities requiring mental alertness, such as driving, if affected.
  • Medical Conditions: Inform your doctor if you have liver, kidney, or heart problems, high blood pressure, high cholesterol, diabetes, asthma, inflammatory bowel disease, stomach ulcers, bleeding disorders, or a history of alcohol abuse. Dosage adjustments may be needed for those with liver or kidney disease.
  • Children and Elderly: Not recommended for children as safety and efficacy have not been established. Caution is advised in the elderly due to increased susceptibility to side effects.
  • Drug Interactions: Inform your doctor about all other medications you are taking to avoid potential drug-drug interactions, especially other painkillers or muscle relaxants.

• Storage Store NOBEL MR TAB in a cool and dry place, away from direct sunlight and moisture, at room temperature (20-25°C). Keep out of reach and sight of children.

NOBEL MR TAB by MANKIND PHARMA LTD is a combination medicine used to relieve pain and inflammation, particularly that associated with muscle spasms. It contains Nimesulide (a non-steroidal anti-inflammatory drug), Paracetamol (an analgesic and antipyretic), and Tizanidine (a muscle relaxant).

Here are some frequently asked questions about NOBEL MR TAB:

What is NOBEL MR TAB used for?

NOBEL MR TAB is primarily used to alleviate pain due to muscle spasms and inflammation. It is prescribed for conditions such as osteoarthritis, muscle pain, tooth pain, bone and joint pain, headaches, and period pain.

How does NOBEL MR TAB work?

This medicine combines three active ingredients: Nimesulide, Paracetamol, and Tizanidine. Nimesulide and Paracetamol work by blocking chemical messengers in the brain that cause pain and inflammation. Tizanidine acts as a muscle relaxant, working on the spinal cord and brain to reduce muscle stiffness and improve muscle movement.

What is the usual dosage for NOBEL MR TAB?

The dosage of NOBEL MR TAB should be taken exactly as advised by your doctor. It is generally recommended to take the tablet with food to prevent stomach upset. The tablet should be swallowed whole and not chewed, crushed, or broken.

What are the possible side effects of NOBEL MR TAB?

Common side effects may include nausea, vomiting, diarrhea, sleepiness, weakness, increased liver enzymes, and dry mouth. If these side effects persist or worsen, it is advisable to consult your doctor.

Is NOBEL MR TAB safe during pregnancy or breastfeeding?

NOBEL MR TAB is generally not recommended during pregnancy, especially during the first and third trimesters, as there is evidence of risk to the developing baby. It should also be avoided during breastfeeding because the safety of its components in infants has not been established, and it is unknown if Nimesulide is secreted in breast milk. Always consult your doctor before taking this medicine if you are pregnant or breastfeeding.

Can NOBEL MR TAB be taken with other medications?

There is a potential for drug-drug interactions with NOBEL MR TAB. It is crucial to inform your doctor about all other medications you are currently taking to avoid unwanted interactions. Taking other pain relievers or NSAIDs with NOBEL MR TAB is generally not advisable without medical consultation, as it may increase the risk of side effects like gastric ulceration and bleeding. Critical interactions with Tizanidine-containing medications and certain other drugs like Piroxicam and Indomethacin have been noted.

What precautions should be taken while using NOBEL MR TAB?

Avoid consuming alcohol while taking NOBEL MR TAB as it can increase the risk of stomach problems and dizziness. This medicine may cause dizziness or sleepiness, so caution is advised when driving or operating machinery. It should be used with caution in elderly patients and those with pre-existing liver or kidney conditions. The medicine is not recommended for children, and the prescribed dosage should not be exceeded.

What happens if a dose of NOBEL MR TAB is missed?

If you miss a dose of NOBEL MR TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should NOBEL MR TAB be stored?

NOBEL MR TAB should be stored in a cool and dry place, away from direct sunlight, and out of the reach and sight of children. It is recommended to store it below 30°C and protect it from moisture and light.