Zedocef Cv 200 ( 10 Tablet )

ZEDOCEF CV 200 (10 TABLET)

ZEDOCEF CV 200 is a broad-spectrum antibiotic manufactured by Macleods Pharmaceuticals Ltd., used to combat a variety of bacterial infections. It is a combination medicine designed to effectively treat infections while countering bacterial resistance.

• Name:

  • Brand Name: ZEDOCEF CV 200
  • Manufacturer: MACLEODS PHARMACEUTICALS LTD.

• Composition:

  • Each tablet contains Cefpodoxime Proxetil 200 mg and Clavulanic Acid 125 mg.
  • Cefpodoxime is a third-generation cephalosporin antibiotic that works by inhibiting bacterial cell wall synthesis.
  • Clavulanic Acid is a beta-lactamase inhibitor that prevents bacteria from deactivating Cefpodoxime, thereby enhancing its effectiveness.

• Uses: ZEDOCEF CV 200 is prescribed for the treatment of various bacterial infections, including:

  • Respiratory tract infections (e.g., acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, community-acquired pneumonia, pharyngitis, tonsillitis).
  • Ear infections (otitis media).
  • Sinus infections (sinusitis).
  • Urinary tract infections.
  • Skin and skin structure infections.
  • Sexually transmitted infections such as gonorrhoea and anorectal infections in women.

• Dosage and Administration:

  • Typically, it is advised to swallow the tablet whole with a glass of water.
  • It can be taken with or without food, but it is better to take it at a fixed time daily for optimal efficacy.
  • The exact dose and duration will be determined by a healthcare professional based on the patient's condition and infection severity. For sinusitis, a common dosage mentioned is 1 tablet, twice daily for 10 days.
  • It is crucial to complete the entire course of treatment, even if symptoms improve, to prevent re-infection and antibiotic resistance.

• Side Effects: Common side effects may include:

  • Diarrhoea, nausea, vomiting, abdominal pain, indigestion.
  • Headache.
  • Vaginal fungal infections or vulvovaginal infections.
  • Less common: Dizziness, hives, insomnia, decreased appetite. Serious allergic reactions (e.g., itchy rash, swelling of the face, throat, or tongue, difficulty breathing) require immediate medical attention.

• Precautions:

  • Allergies: Contraindicated in patients with known allergies to Cefpodoxime, Clavulanic Acid, or other cephalosporin or penicillin antibiotics.
  • Kidney/Liver Disease: Use with caution in patients with severe kidney disease, as dosage adjustments may be necessary. Caution is also advised for patients with liver disease.
  • Gastrointestinal Diseases: Use cautiously if there is a history of gastrointestinal diseases, particularly colitis, due to the potential risk of Clostridium difficile-associated diarrhoea.
  • Pregnancy and Breastfeeding: Pregnant women should use this medicine with caution only if clearly necessary. It is not recommended for breastfeeding women as it may pass into breast milk.
  • Drug Interactions: May interact with probenecid (increasing Cefpodoxime levels), oral contraceptives (reducing effectiveness), and warfarin (enhancing its blood-thinning effect).
  • Alcohol: While there's no known interaction between alcohol and ZEDOCEF CV 200, it's advised to avoid alcohol if dizziness occurs.
  • Driving/Operating Machinery: May cause dizziness; exercise caution when driving or operating machinery.
  • Pediatric Use: Generally indicated for use in children and adolescents aged above 12 years, but not recommended for children below 8 years.

• Storage:

  • Store ZEDOCEF CV 200 in its original container at room temperature, ideally between 20 to 25°C or below 30°C.
  • Protect from direct sunlight and excessive moisture.
  • Keep out of sight and reach of children.
  • Do not use expired medicine.

What is Zedocef CV 200 Tablet used for?

Zedocef CV 200 Tablet is an antibiotic primarily used to treat various bacterial infections. These include infections of the respiratory tract (such as acute otitis media, pharyngitis/tonsillitis, acute bacterial sinusitis, chronic bronchitis, and community-acquired pneumonia), urinary tract, skin, throat, ear, and sinuses. It is also effective against certain sexually transmitted diseases like gonorrhoea and anorectal infections in women.

How does Zedocef CV 200 Tablet work?

Zedocef CV 200 Tablet is a combination of two active ingredients: Cefpodoxime Proxetil (200 mg) and Clavulanic Acid (125 mg). Cefpodoxime Proxetil is a cephalosporin antibiotic that works by preventing the formation of the bacterial cell wall, which is essential for the bacteria's survival. This action stops the growth and multiplication of bacteria, ultimately killing them. Clavulanic Acid is a beta-lactamase inhibitor. Some bacteria produce beta-lactamase enzymes that can break down antibiotics like Cefpodoxime Proxetil, making them ineffective. Clavulanic Acid blocks these enzymes, reducing bacterial resistance and enhancing Cefpodoxime's activity against a broader range of bacteria.

What is the usual dosage for Zedocef CV 200 Tablet?

The dosage of Zedocef CV 200 Tablet is determined by a doctor based on the severity of the condition, the patient's age, weight, and response to treatment. For conditions like sinusitis, a typical dosage might be one tablet twice daily for 10 days. It should be taken orally, whole with a glass of water, and not chewed or crushed. The medicine can be taken with or without food, but it is often advised to take it at a fixed time daily for better efficacy.

What are the possible side effects of Zedocef CV 200 Tablet?

Common side effects can include nausea, vomiting, diarrhea, indigestion, abdominal pain, and headache. Less common side effects may include vaginal fungal infections or vulvovaginal infections. If you experience severe diarrhea, an itchy rash, swelling of the face, throat, or tongue, or breathing difficulties, you should seek immediate medical attention as these could be signs of an allergic reaction.

Is Zedocef CV 200 Tablet safe during pregnancy or breastfeeding?

Zedocef CV 200 Tablet should be used with caution during pregnancy and only if clearly necessary, after consulting a doctor to weigh the potential benefits against risks. It is generally not recommended for use in breastfeeding women as it may pass into breast milk and affect the baby. Always consult your doctor before taking this medicine if you are pregnant or breastfeeding.

Can Zedocef CV 200 Tablet be taken with other medications?

Zedocef CV 200 Tablet can interact with certain medications. Probenecid might increase the levels of Cefpodoxime Proxetil in your blood, potentially leading to more side effects. It could also reduce the effectiveness of oral contraceptives, so additional contraceptive methods may be advised. There is a possibility that Cefpodoxime Proxetil could enhance the blood-thinning effect of warfarin, increasing the risk of bleeding. Concomitant use of acid-lowering medicines like antacids (e.g., sodium bicarbonate, aluminium hydroxide, ranitidine, cimetidine) can decrease the effect of Zedocef CV 200 Tablet. It may also interact with live vaccines. It is crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid possible interactions.

What precautions should be taken while using Zedocef CV 200 Tablet?

Avoid Zedocef CV 200 Tablet if you are allergic to cefpodoxime, clavulanic acid, penicillins, or other cephalosporin antibiotics. Use with caution if you have severe kidney disease, liver disease, or a history of gastrointestinal diseases, particularly colitis, as dosage adjustments or close monitoring may be necessary. It's important to complete the full prescribed course of treatment even if you start to feel better, to prevent the infection from returning and to avoid antibiotic resistance. While there's no known interaction with alcohol, excessive consumption might reduce its effectiveness. Zedocef CV 200 Tablet may cause dizziness, so caution is advised when driving or operating machinery.

What happens if a dose of Zedocef CV 200 Tablet is missed?

If you miss a dose of Zedocef CV 200 Tablet, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should Zedocef CV 200 Tablet be stored?

Zedocef CV 200 Tablet should be stored in its original container at room temperature, ideally between 20 to 25°C or below 30°C. It should be protected from direct sunlight and excessive moisture. Always keep the medicine out of the reach and sight of children. Ensure the medicine is used before its expiry date.