Citistar 2ml Inj

CITISTAR 2ML INJ by LUPIN LTD

CITISTAR 2ML INJ is a medication primarily used for its neuroprotective and neurogenerative properties.

• Name:

  • Brand Name: CITISTAR 2ML INJ, Citistar 2 Injection, Citistar 250mg Injection
  • Common Name: Citicoline Injection

• Composition:

  • Active Ingredient: Citicoline 250mg per 2ml

• Uses: CITISTAR 2ML INJ is prescribed to manage disturbances of consciousness resulting from various neurological conditions in adults. These include:

  • Head injuries
  • Brain operations
  • Acute cerebral infarction (stroke), aiding recovery and diminishing brain damage
  • Alzheimer's disease, to improve cognitive functions and memory
  • Memory loss associated with Parkinson's disease
  • Glaucoma

• Dosage and Administration: This injection should be administered by a healthcare professional only. It can be given as a slow intravenous infusion or a deep intramuscular injection. The dosage and duration are determined by the doctor based on the individual's medical condition and response. It should not be self-administered.

• Side Effects: Common side effects may include:

  • Injection site reactions (pain, redness, swelling)
  • Digestive issues (nausea, vomiting, stomach pain, diarrhoea)
  • Insomnia (difficulty sleeping)
  • Headache
  • Skin rash
  • Decreased blood pressure
  • Irregular heart rate (arrhythmia)
  • Feeling of warmth, loss of appetite, convulsions, transient diplopia (double vision), and dyspnea (shortness of breath) Serious but rare side effects can include signs of shock (e.g., drop in blood pressure, chest distress, shortness of breath).

• Precautions:

  • Not recommended for patients with known allergy to Citicoline or other ingredients.
  • Avoid if experiencing hypertonia (increased muscle spasms and rigidity) or persistent intracranial haemorrhages (brain bleed).
  • Caution is advised in pregnant and breastfeeding women; use only if clearly necessary after consulting a doctor.
  • Patients with a history of epilepsy/fits, liver, or severe kidney problems should use with caution.
  • Inform your doctor about all current medications, especially levodopa (used for Parkinson's disease), as it may increase its effect, and meclofenoxate (oral contraceptives or dietary supplement) which should not be used concurrently.
  • May cause irregular body movement and double vision, so caution is advised when driving or operating machinery.

• Storage: Store in a cool and dry place, protected from light, and below 25°C or 30°C. Do not freeze. Keep out of reach of children and pets.

Here are some frequently asked questions about CITISTAR 2ML INJ (Citicoline injection) along with concise answers:

What is CITISTAR 2ML INJ used for?

CITISTAR 2ML INJ, which contains Citicoline, is primarily used to manage disturbances of consciousness resulting from conditions like head injuries, brain operations, and acute cerebral infarction (stroke). It is also used in the treatment of Alzheimer's disease, memory loss associated with Parkinson's disease, cerebrovascular disorders, cognitive impairment, vascular dementia, and glaucoma.

How does CITISTAR 2ML INJ work?

Citicoline works by increasing the synthesis of phosphatidylcholine, a crucial component of nerve cell membranes. This action helps to repair and stabilize damaged neuronal membranes. It also reduces the accumulation of free fatty acids at injury sites, enhances the synthesis of neurotransmitters like acetylcholine and dopamine, and improves blood flow and oxygen consumption in the brain, thereby protecting nerve cells and promoting recovery.

What is the usual dosage for CITISTAR 2ML INJ?

The dosage is individualized based on the severity of the condition. For injections (intramuscular or slow intravenous), common dosages range from 500mg to 1000mg per 24 hours, often administered as one to two injections daily. Slow intravenous administration (over 3-5 minutes) or intravenous infusion (at a rate of 40-60 drops/minute) is typically preferred. For acute cerebral infarction, 1000mg once daily for two consecutive weeks may be prescribed.

What are the possible side effects of CITISTAR 2ML INJ?

Common side effects are generally mild and temporary, and may include headache, sleeplessness (insomnia), dizziness, nausea, diarrhea, stomach pain, restlessness, blurred vision, or reactions at the injection site. Less common effects can include irregular heartbeat, low blood pressure (hypotension), high blood pressure, tachycardia, bradycardia, rash, fatigue, loss of appetite, convulsions, or feeling of warmth.

Is CITISTAR 2ML INJ safe during pregnancy or breastfeeding?

The safety and efficacy of Citicoline during pregnancy and breastfeeding have not been clinically established, and there isn't enough reliable information. It should only be used if the potential benefits clearly justify the potential risks to the fetus or infant. It is crucial to consult your doctor if you are pregnant, planning pregnancy, or breastfeeding before taking this medicine.

Can CITISTAR 2ML INJ be taken with other medications?

Citicoline should not be administered with medications containing meclofenoxate (clophenoxate). It also potentiates the effects of L-dopa (levodopa, carbidopa, and entacapone), which are used to manage Parkinson's disease. Always inform your doctor about all other medications, including herbal supplements, you are currently taking to avoid potential drug interactions.

What precautions should be taken with CITISTAR 2ML INJ?

Inform your doctor if you have any allergies to Citicoline, have kidney or liver problems, epilepsy/fits, depression, or if you have hypertonia (muscle overactivity) of the parasympathetic nervous system. In cases of persistent intracranial hemorrhage, the injection should be administered very slowly. It is advised to avoid alcohol during treatment as it can reduce the effectiveness and worsen neurological conditions. CITISTAR 2ML INJ is not generally recommended for children. This medication is administered by a healthcare professional and should not be self-administered.

What happens if a dose of CITISTAR 2ML INJ is missed?

Since CITISTAR 2ML INJ is an injectable medication administered by a qualified healthcare professional in a hospital or clinic setting, the likelihood of missing a dose is very low. If an appointment for the injection is missed, contact your doctor or nurse as soon as possible to reschedule and receive the replacement dose. Do not attempt to take a double dose to compensate for a missed one.

How should CITISTAR 2ML INJ be stored?

CITISTAR 2ML INJ should be stored in a cool and dry place, protected from light and moisture, at a temperature not exceeding 25°C or 30°C. It should not be frozen. Always keep this medicine out of the reach of children.