Pivasta 1 Mg Tablet (10 Tab)

PIVASTA 1 MG TABLET

PIVASTA 1 MG Tablet, manufactured by Zydus Healthcare Limited, is a medication used to manage cholesterol levels in the body. It belongs to a class of drugs known as statins.

• Name:

  • Brand Name: Pivasta 1 MG Tablet
  • Common Name: Pitavastatin

• Composition:

  • Each tablet contains Pitavastatin 1 mg.

• Uses: PIVASTA 1 MG Tablet is primarily used for:

  • Reducing high levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood.
  • Boosting levels of "good" cholesterol (high-density lipoprotein, or HDL).
  • Lowering overall blood cholesterol for a healthier heart.
  • Preventing heart attacks and strokes by managing cholesterol levels.
  • Managing heterozygous familial hypercholesterolemia (HeFH), a genetic condition causing high cholesterol levels, in children over 8 years old.

• Dosage and Administration:

  • Pivasta 1 MG Tablet is taken orally.
  • It is typically taken once daily, with or without food, but preferably at a fixed time each day.
  • Tablets should be swallowed whole with a glass of water and not chewed, crushed, or broken.
  • The starting dose for adults is often 1 to 2 mg once daily, with a maximum recommended dose of 4 mg daily, adjusted based on individual response and cholesterol levels.
  • Dosage adjustments may be required for patients with kidney or liver problems.

• Side Effects:

  • Common Side Effects: Muscle pain, back pain, diarrhea, constipation, pain in extremities (arms and legs), and memory problems.
  • Serious Side Effects: Liver problems (signs include dark urine, pale stools, severe nausea, loss of appetite, stomach pain, unusual tiredness, yellowing of skin or eyes), muscular problems such as myopathy or rhabdomyolysis (severe muscle pain, tenderness, or weakness), and severe allergic reactions (rash, hives, itching, difficulty breathing, tightness in the chest, swelling of the mouth, face, lips, or tongue).

• Precautions:

  • Pregnancy and Breastfeeding: Pivasta 1 MG Tablet is contraindicated during pregnancy and breastfeeding. Women of childbearing potential should use effective birth control measures.
  • Liver Disease: Avoid use in patients with active liver disease or unexplained, persistent elevations in liver enzymes.
  • Kidney Disease: Use with caution in patients with kidney disease; dose adjustments may be necessary.
  • Alcohol Consumption: Caution is advised when consuming alcohol, as it may increase the risk of liver problems.
  • Diabetes: Monitor blood sugar levels closely in diabetic patients, as this medicine may increase blood glucose.
  • Muscle Disorders: Use with caution in patients with a history of muscle disorders. Report any unexplained muscle pain or weakness promptly.
  • Drug Interactions: Inform your doctor about all medications, including other cholesterol-lowering drugs (fibrates), immunosuppressants (cyclosporine), and certain antibiotics (erythromycin, rifampin), as interactions can occur.
  • Regular monitoring of liver function tests is recommended before and during treatment.

• Storage:

  • Store below 30°C.
  • Keep in a dry place and away from light.
  • Keep out of reach of children.

What is Pivasta 1 MG Tablet used for?

Pivasta 1 MG Tablet is primarily used in adults, along with a healthy diet and exercise, to lower high levels of "bad" cholesterol (Low-Density Lipoprotein or LDL) and triglycerides in the blood. It also helps to increase "good" cholesterol (High-Density Lipoprotein or HDL) and reduce high total cholesterol. By improving cholesterol levels, it aims to reduce the risk of heart attack and stroke. It can also be prescribed for children aged 8 years and older with heterozygous familial hypercholesterolemia (HeFH), an inherited condition causing high cholesterol.

How does Pivasta 1 MG Tablet work?

Pivasta 1 MG Tablet contains the active ingredient Pitavastatin, which belongs to a class of medicines called statins. It works by inhibiting an enzyme in the liver called HMG-CoA reductase. This enzyme is crucial for the body to produce cholesterol. By blocking this enzyme, Pitavastatin slows down the production of cholesterol, thereby lowering the levels of bad cholesterol (LDL) and triglycerides and increasing good cholesterol (HDL) in the blood.

What is the usual dosage for Pivasta 1 MG Tablet?

For adults, the typical dosage of Pitavastatin (the active ingredient in Pivasta) ranges from 1 mg to 4 mg, taken once per day. The specific dose is individualized based on the patient's cholesterol levels, the goals of therapy, and their response to the medication. It can be taken with or without food, but it's advisable to take it at the same time each day. For patients with moderate to severe kidney impairment or those on hemodialysis, the recommended starting dose is 1 mg once daily, with a maximum dose of 2 mg once daily.

What are the possible side effects of Pivasta 1 MG Tablet?

Common side effects of Pivasta 1 MG Tablet may include back pain, constipation, diarrhea, muscle aches, and pain in the arms or legs. More serious side effects, though rare, can include:

• Muscle problems: This can manifest as unexplained muscle pain, tenderness, or weakness, and in severe cases, can lead to rhabdomyolysis, a serious muscle breakdown that can cause kidney failure.
• Liver problems: Pitavastatin can cause increases in liver enzymes and, rarely, lead to liver failure. Symptoms may include extreme tiredness, loss of appetite, pain in the upper right abdomen, dark urine, or yellowing of the skin or eyes.
• High blood sugar: It can increase blood sugar levels, especially in individuals with diabetes.
• Allergic reactions: Symptoms can include rash, itching, hives, or swelling of the face, lips, tongue, or throat.

It is important to report any serious or persistent side effects to your doctor immediately.

Is Pivasta 1 MG Tablet safe during pregnancy or breastfeeding?

Pivasta 1 MG Tablet (Pitavastatin) is generally not safe for use during pregnancy and is contraindicated. It may cause fetal harm because cholesterol products are essential for fetal development, and this medication decreases cholesterol synthesis. Similarly, it is not recommended during breastfeeding. Although it is unknown if Pitavastatin passes into human milk, other drugs in its class have been detected, and there is a potential for serious adverse reactions in breastfed infants. Women of childbearing potential should use effective contraception while taking this medication.

Can Pivasta 1 MG Tablet be taken with other medications?

Pivasta 1 MG Tablet can interact with several other medications, which may increase the risk of side effects. It is important to inform your doctor about all prescription, non-prescription, herbal products, and dietary supplements you are taking. Some significant interactions include:

• Cyclosporine: Concomitant use is contraindicated as it significantly increases pitavastatin exposure and the risk of muscle problems.
• Gemfibrozil (and other fibrates): Concomitant use is not recommended due to an increased risk of myopathy and rhabdomyolysis.
• Erythromycin: The dosage of Pitavastatin should not exceed 1 mg once daily when taken with erythromycin.
• Rifampin: The dosage of Pitavastatin should not exceed 2 mg once daily when taken with rifampin.
• Warfarin: Using Pitavastatin with this blood-thinning drug may increase the effects of warfarin, raising the risk of bleeding.
• Niacin and Colchicine: Concomitant use may increase the risk of muscle problems.
• Alcohol: Large amounts of alcohol can increase the risk of serious liver damage when taken with Pitavastatin.

Your doctor may need to adjust doses or monitor you closely for side effects if you are taking interacting medications.

What precautions should be taken while taking Pivasta 1 MG Tablet?

Before taking Pivasta 1 MG Tablet, inform your doctor if you have or have had:

• Liver disease or drink large amounts of alcohol: Pitavastatin can cause liver problems, and active liver disease or significant alcohol consumption is a contraindication.
• Kidney disease: Dose adjustments may be necessary, and you may be at increased risk for muscle problems.
• Underactive thyroid (hypothyroidism) that is not well controlled: This can increase the risk of muscle problems.
• Diabetes: Pitavastatin can increase blood sugar levels, and these should be monitored closely.
• Unexplained muscle pain, tenderness, or weakness: Report these symptoms immediately to your doctor, especially if accompanied by fever or unusual tiredness, as they could indicate serious muscle injury. Regular blood and urine tests may be needed to monitor progress and check for unwanted effects.

What happens if a dose is missed?

If you miss a dose of Pivasta 1 MG Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. Some sources suggest if it's been more than 12 hours since you missed your last dose, you should skip it.

How should Pivasta 1 MG Tablet be stored?

Pivasta 1 MG tablets should be stored at room temperature, typically between 15°C and 30°C (59°F to 86°F). Keep the medicine in its closed container, away from heat, moisture, and direct light. Do not freeze the tablets. Always keep this and all medications out of the reach of children and pets. Discard any unused medication after the expiration date.