Ampoxindry Syrup (30 Ml)

AMPOXIN DRY SYRUP (30 ML) by TORRENT PHARMACEUTICALS LTD

AMPOXIN DRY SYRUP is an antibiotic medication manufactured by Torrent Pharmaceuticals Ltd, specifically formulated to treat a wide range of bacterial infections. It is primarily used in children.

Composition

AMPOXIN DRY SYRUP contains a combination of two penicillin antibiotics:

• Ampicillin (125 mg)
• Cloxacillin (125 mg)

Ampicillin is a broad-spectrum antibiotic that inhibits bacterial cell wall synthesis. Cloxacillin also works by preventing bacteria from forming cell walls and is effective against penicillinase-producing bacteria, enhancing the overall efficacy against resistant strains.

Uses

AMPOXIN DRY SYRUP is prescribed for various bacterial infections, including:

• Respiratory Tract Infections: Such as bronchopneumonia, acute exacerbations of chronic bronchitis, pneumonia, and tonsillitis.
• Ear, Nose, and Throat Infections: Including otitis media, sinusitis, and throat infections.
• Skin and Soft Tissue Infections: Like cellulitis, impetigo, and infected wounds.
• Urinary Tract Infections (UTIs).
• Bone and Joint Infections, including osteomyelitis.
• Post-operative Infections: Such as wound infections and lung infections following surgery.
• Other infections: Including septicaemia, puerperal fever, typhoid fever, dental infections, and endocarditis.

Dosage and Administration

The dosage of AMPOXIN DRY SYRUP is determined by a physician based on the severity of the infection, the patient's age, weight, and kidney function.

• The dry powder should be dissolved in sterile water and shaken well before use.
• It is typically administered three times a day.
• For optimal absorption, it is best given on an empty stomach, ideally 30 minutes to one hour before a meal. However, if stomach upset occurs, it can be given with food.
• A calibrated measuring device (syringe or medicine cup) should be used for accurate dosing.
• It is crucial to complete the entire prescribed course of antibiotics, even if symptoms improve, to prevent recurrence and antibiotic resistance.
• If a child vomits within 30 minutes of taking a dose, repeat the dose once they feel better. Do not double the dose if it is close to the next scheduled dose.

Side Effects

Common side effects may include:

• Diarrhea
• Nausea and vomiting
• Abdominal pain
• Skin rash, urticaria, and pruritus
• Headache

Serious or less common side effects that require immediate medical attention include severe allergic reactions (e.g., anaphylaxis, facial swelling, difficulty breathing), liver problems, blood disorders, and severe diarrhea with bleeding or abdominal cramps (indicating superinfection).

Precautions

• Inform your doctor about any allergies, especially to penicillin antibiotics (Ampicillin, Cloxacillin) or other beta-lactam antibiotics (e.g., cephalosporins).
• Use with caution in patients with liver or kidney disease; dose adjustments and regular monitoring may be necessary.
• There is no proper information on its use during pregnancy and breastfeeding; consult a doctor.
• Caution is advised in neonates with jaundice and in elderly patients (65 years and above).
• This medicine is only effective against bacterial infections and should not be used for viral infections like the common cold or flu.
• Long-term or improper use can lead to the overgrowth of non-susceptible organisms, severe gastrointestinal infections, and antibiotic resistance.
• Inform your doctor about all other medications your child is taking to avoid potential drug interactions.

Storage

AMPOXIN DRY SYRUP should be stored in a cool, dry place, away from direct sunlight and moisture, at room temperature (15-25ºC or below 30ºC). Keep it out of reach of children. The prepared suspension typically needs to be used within 7-14 days; discard any unused portion after this period. Ensure the bottle is tightly closed when not in use.

AMPOXINDRY SYRUP (30 ML) by TORRENT PHARMACEUTICALS LTD is an antibiotic medication containing a combination of Ampicillin and Cloxacillin. It is used to treat various bacterial infections.

What is Ampoxin Dry Syrup used for?

Ampoxin Dry Syrup is primarily used to treat a wide range of bacterial infections. These include infections of the respiratory tract (such as bronchitis, pneumonia, and tonsillitis), ear, nose, and throat (like sinusitis and otitis media), skin and soft tissues (e.g., cellulitis, impetigo, infected wounds), urinary tract, bone infections (osteomyelitis), and post-operative wound infections. It is a broad-spectrum antibiotic effective against both gram-positive and gram-negative bacteria.

How does Ampoxin Dry Syrup work?

Ampoxin Dry Syrup contains two antibiotics: Ampicillin and Cloxacillin. Both belong to the penicillin class and work by preventing the formation of bacterial cell walls, which are vital for the bacteria's survival. Cloxacillin also helps by counteracting the penicillinase enzyme, produced by some bacteria, that can make Ampicillin ineffective. This combined action ensures broader coverage and enhanced efficacy against various bacterial strains.

What is the usual dosage for Ampoxin Dry Syrup?

The dosage of Ampoxin Dry Syrup is determined by a physician, based on the severity of the infection, the patient's age, and kidney function. Generally, it is advised to take the medication on an empty stomach, at least 30 minutes before meals, to improve absorption. For specific guidance, particularly for children, a doctor or pharmacist should be consulted.

What are the possible side effects of Ampoxin Dry Syrup?

Common side effects include diarrhea, nausea, vomiting, stomach upset, and skin rash. If you experience persistent or severe diarrhea with abdominal pain, or signs of a serious allergic reaction such as an itchy rash, swelling of the face, throat, or tongue, or difficulty breathing, seek immediate medical attention.

Is Ampoxin Dry Syrup safe during pregnancy or breastfeeding?

During Pregnancy: Ampoxin Dry Syrup can be taken during pregnancy, but it's important to consult your doctor. They may want to assess its suitability, especially in certain situations like if your waters break early. During Breastfeeding: It is generally considered acceptable to use while breastfeeding, as it passes into breast milk in small amounts and is unlikely to cause significant side effects in the baby. However, mild side effects such as the baby not feeding as well, vomiting, diarrhea, oral thrush, skin rash, or restlessness have been reported in some infants. It is advisable to consult your doctor or health visitor and monitor the baby for any unusual symptoms.

Can Ampoxin Dry Syrup be taken with other medications?

It's crucial to inform your doctor about all other medications you are taking. Ampoxin Dry Syrup should be avoided with methotrexate due to the risk of serious side effects. Medications like probenecid and allopurinol can increase the levels of ampicillin in the blood, potentially increasing side effects. It may also reduce the effectiveness of oral contraceptives. Bacteriostatic antibiotics (such as chloramphenicol, erythromycin, and tetracycline) may interfere with its action. Avoiding alcohol while taking this medication is also recommended.

What precautions should be taken while using Ampoxin Dry Syrup?

Do not use this medicine if you have a known allergy to penicillin or cephalosporins. Inform your doctor if you have had diarrhea after taking antibiotics previously or have inflammation of the bowel. It is essential to complete the entire prescribed course of treatment, even if you start to feel better, to ensure the infection is fully eradicated and to prevent antibiotic resistance. If stomach upset occurs, taking it with food might help.

What happens if a dose of Ampoxin Dry Syrup is missed?

If a dose is missed, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should Ampoxin Dry Syrup be stored?

Ampoxin Dry Syrup should be stored in a cool, dry place, away from direct sunlight, and out of the reach of children. Once reconstituted with water, the suspension should be stored below 25°C and must be consumed within 3 days. Do not freeze the liquid form of the medication.