Rozat 40 Mg Tablet (15 Tab)

ROZAT 40 MG TABLET is a medication manufactured by Dr. Reddy's Laboratories Ltd., primarily used to manage high cholesterol and triglyceride levels in the blood. This medicine belongs to a class of drugs known as statins.

Name

• Brand Name: ROZAT 40 MG TABLET
• Common Name: Rosuvastatin (a statin)

Composition

The active ingredient in ROZAT 40 MG TABLET is Rosuvastatin 40 mg.

Uses

ROZAT 40 MG TABLET is prescribed for:

• Lowering high cholesterol levels (hyperlipidemia).
• Reducing elevated triglyceride levels (hypertriglyceridemia).
• Preventing cardiovascular diseases such as heart attack and stroke by reducing the buildup of fatty deposits in arteries (atherosclerosis).
• Managing Type 3 Hyperlipoproteinemia.
• Increasing levels of "good" cholesterol (HDL).

Dosage and Administration

The typical dosage for adults is one tablet taken orally once a day, with or without food. It is advisable to take the medicine at the same time each day for consistency. Do not crush or chew the tablet; swallow it whole with a glass of water. The dosage may be adjusted by a healthcare professional based on individual cholesterol levels, medical history, and response to treatment.

Side Effects

Common side effects include:

• Headache
• Muscle pain/weakness (myalgia, asthenia)
• Nausea
• Constipation
• Dizziness
• Abdominal pain/stomach discomfort

Serious side effects are less common, but if muscle pain or weakness persists or is accompanied by dark urine, or if there are signs of liver problems (e.g., yellowing of eyes/skin, stomach pain), a doctor should be consulted.

Precautions

• Pregnancy and Breastfeeding: ROZAT 40 MG TABLET is contraindicated during pregnancy and breastfeeding as it may harm the fetus or nursing infant. Women of childbearing age should use effective contraception.
• Liver Disease: Avoid use in individuals with severe or active liver disease. Caution is advised for those with liver impairment.
• Kidney Disease: Use with caution in patients with kidney problems; a lower dose may be required in severe renal impairment.
• Alcohol: Limit alcohol consumption as it may increase the risk of liver side effects and can increase triglyceride levels.
• Drug Interactions: Inform your doctor about all medicines you are taking, especially immunosuppressants (like cyclosporine), fibrates (like gemfibrozil), certain antiviral medications, and blood thinners (like warfarin), as interactions can occur.
• Other Conditions: Use with caution in patients with diabetes, hypothyroidism, or a family history of muscle disorder. Diabetic individuals should monitor blood sugar levels.
• Children: Not recommended for children under 6 years of age. For children 8 years or older with familial hypercholesterolemia, it may be prescribed under medical supervision.
• Elderly Patients: Use with caution in older adults, especially those above 70, as they may be more susceptible to side effects.

Storage

Store ROZAT 40 MG TABLET at a cool room temperature, below 30°C. Protect from moisture and light, and keep it in a dry area away from heat sources. Keep out of reach and sight of children.

ROZAT 40 MG Tablet contains rosuvastatin, which belongs to a class of medicines called statins. It is primarily used to manage high cholesterol levels and reduce the risk of cardiovascular events.

What is ROZAT 40 MG Tablet used for?

ROZAT 40 MG Tablet is used to lower high levels of "bad" cholesterol (LDL) and triglycerides in the blood, while also increasing "good" cholesterol (HDL). By doing so, it helps to reduce the risk of heart disease, heart attacks, and strokes, and slows down the progression of atherosclerosis (hardening of the arteries).

How does ROZAT 40 MG Tablet work?

This medicine works by inhibiting an enzyme in the liver called HMG-CoA reductase, which is crucial for cholesterol production. By blocking this enzyme, ROZAT 40 MG Tablet reduces the liver's production of harmful cholesterol and improves its ability to remove existing cholesterol from the blood.

What is the usual dosage for ROZAT 40 MG Tablet?

For adults, the typical dose of rosuvastatin ranges from 5 mg to 40 mg once daily. The 40 mg dose is generally reserved for patients whose cholesterol levels are not adequately lowered by a 20 mg dose and who are at a high risk of heart attacks or strokes. It can be taken at any time of day, with or without food, but it's best to take it at the same time daily to maintain consistency.

What are the possible side effects of ROZAT 40 MG Tablet?

Common side effects can include headache, muscle pain (myalgia), weakness (asthenia), constipation, dizziness, nausea, and abdominal pain. If these effects persist or worsen, consult your doctor. More serious, though rare, side effects may include severe muscle problems like rhabdomyolysis (muscle breakdown that can lead to kidney damage) and liver problems (signs include yellowing of the skin or eyes, dark urine). If you experience unexplained muscle pain, tenderness, weakness, or symptoms of liver issues, seek immediate medical attention. ROZAT 40 MG Tablet may also lead to small increases in blood sugar levels, particularly in individuals with diabetes.

Is ROZAT 40 MG Tablet safe during pregnancy or breastfeeding?

No, ROZAT 40 MG Tablet is contraindicated during pregnancy as it can harm the developing fetus. Women of childbearing age should use effective contraception while taking this medication. It is also not recommended during breastfeeding because rosuvastatin can pass into breast milk and potentially harm the infant.

Can ROZAT 40 MG Tablet be taken with other medications?

ROZAT 40 MG Tablet can interact with certain medications. It should not be taken with cyclosporine (an immunosuppressant), and its dose should not exceed 5 mg daily if co-administered. Concomitant use with gemfibrozil (another cholesterol-lowering drug) should be avoided, or the rosuvastatin dose should not exceed 10 mg daily. Certain HIV protease inhibitors (like atazanavir and lopinavir), blood thinners (e.g., warfarin), erythromycin, aluminium hydroxide, ketoconazole, fusidic acid, and colchicine may also interact with ROZAT 40 MG Tablet. Antacids containing aluminum and magnesium should be taken at least 2 hours after ROZAT 40 MG Tablet. Always inform your doctor about all other medications you are taking.

What precautions should be taken while taking ROZAT 40 MG Tablet?

Inform your doctor if you have any pre-existing conditions such as liver disease (it is contraindicated in active liver disease), severe kidney disease, muscle disorders, diabetes, or thyroid problems. Regular monitoring of your cholesterol levels, liver function, and kidney function is recommended during treatment. Limit alcohol consumption, as it can increase the risk of liver problems. If you experience dizziness, avoid driving or operating heavy machinery.

What happens if a dose of ROZAT 40 MG Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should ROZAT 40 MG Tablet be stored?

ROZAT 40 MG Tablet should be stored in a cool and dry place, away from direct sunlight.