Voglistar Gm 1/0.3 Tab

VOGLISTAR GM 1/0.3 TAB by MANKIND PHARMA LTD.

Name

• Brand Name: VOGLISTAR GM 1/0.3 TAB (also known as Voglistar-GM 1/0.3 Tablet, Voglistar GM 1mg/500mg/0.3mg Tablet)
• Manufacturer: Mankind Pharma Ltd.

Composition VOGLISTAR GM 1/0.3 TAB is a fixed-dose combination medication containing three active ingredients:

• Glimepiride (1 mg): A sulfonylurea that stimulates the pancreas to release more insulin, thereby lowering blood sugar levels.
• Metformin (500 mg): A biguanide that reduces glucose production in the liver, delays glucose absorption from the intestines, and enhances the body's response to insulin.
• Voglibose (0.3 mg): An alpha-glucosidase inhibitor that slows down the digestion of complex carbohydrates into simple sugars in the intestine, reducing post-meal blood sugar spikes.

Uses VOGLISTAR GM 1/0.3 TAB is prescribed for the treatment of Type 2 Diabetes Mellitus in adults. It is used when diet, exercise, and single-agent or dual therapy with other antidiabetic drugs are not sufficient to achieve adequate blood sugar control. This medication helps manage blood glucose levels and can reduce the risk of long-term diabetes complications such as kidney damage, eye damage, nerve problems, and cardiovascular events like heart attack or stroke.

Dosage and Administration Take VOGLISTAR GM 1/0.3 TAB orally with meals, as directed by your doctor. The tablet should be swallowed whole with a glass of water and not crushed or chewed. For optimal results, it is recommended to take it at the same time each day. Your doctor will determine the appropriate dosage based on your individual medical condition. Avoid skipping meals while on this medication.

Side Effects

• Common side effects include low blood glucose levels (hypoglycemia), taste changes, nausea, diarrhea, stomach pain, headache, upper respiratory symptoms, loss of appetite, metallic taste, and weight gain.
• Serious side effects that require immediate medical attention include severe hypoglycemia and lactic acidosis (symptoms like extreme fatigue, body weakness, and diarrhea).

Precautions

• Do not take VOGLISTAR GM 1/0.3 TAB if you are allergic to its components, have Type 1 diabetes, diabetic ketoacidosis, severe kidney or liver disease, acute conditions like severe infection, heart problems, are pregnant or breastfeeding, or are a child under 18.
• Avoid alcohol consumption as it increases the risk of hypoglycemia and lactic acidosis.
• Use with caution in elderly patients, and those with a history of liver disease, kidney disease, heart disease, or pancreatitis.
• Inform your doctor about all other medications you are taking, as interactions can occur with other antidiabetic drugs, certain antibiotics, antifungals, corticosteroids, diuretics, and blood thinners.
• Do not stop taking the medication abruptly without consulting your doctor, as this can lead to increased blood sugar levels and associated risks.
• If you experience symptoms of hypoglycemia, consume a source of fast-acting glucose immediately.
• This medication may cause dizziness or blurred vision, so exercise caution when driving or operating machinery.

Storage Store VOGLISTAR GM 1/0.3 TAB in a cool and dry place, away from direct sunlight. Keep it out of sight and reach of children. The medication should be stored at room temperature, typically between 10°C and 25°C, or below 30°C, and protected from moisture and light.

Voglistar GM 1/0.3 Tablet is a combination medication used to manage Type 2 Diabetes Mellitus. It contains Glimepiride, Metformin, and Voglibose, working together to help control blood sugar levels.

Here are some frequently asked questions about Voglistar GM 1/0.3 Tablet:

What is Voglistar GM 1/0.3 Tablet used for?

Voglistar GM 1/0.3 Tablet is used in adults to manage Type 2 Diabetes Mellitus. It is prescribed when diet, exercise, and single-agent or dual therapies are not sufficient to adequately control blood sugar levels.

How does Voglistar GM 1/0.3 Tablet work?

This medicine combines three active ingredients:

• Glimepiride: Stimulates the pancreas to release more insulin, which helps lower blood sugar.
• Metformin: Decreases the amount of glucose produced by the liver and improves the body's sensitivity to insulin, allowing cells to use glucose more effectively.
• Voglibose: Inhibits enzymes in the gut that break down complex carbohydrates into simple sugars, thereby slowing down the absorption of sugar from food and preventing post-meal blood sugar spikes.

Together, these mechanisms help to control blood sugar levels throughout the day.

What is the usual dosage for Voglistar GM 1/0.3 Tablet?

The dosage of Voglistar GM 1/0.3 Tablet should be taken exactly as prescribed by your doctor. It is typically taken with or immediately before meals. The tablet should be swallowed whole with a glass of water and not crushed or chewed. Your doctor will determine the best dose for you based on your medical condition and blood sugar levels.

What are the possible side effects of Voglistar GM 1/0.3 Tablet?

Common side effects may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and hypoglycemia (low blood sugar). More serious but rare side effects can include lactic acidosis, characterized by symptoms like exhaustion, extreme fatigue, body weakness, diarrhea, and headache. If you experience severe side effects or symptoms of hypoglycemia or lactic acidosis, contact your doctor immediately.

Is Voglistar GM 1/0.3 Tablet safe during pregnancy or breastfeeding?

Voglistar GM 1/0.3 Tablet is generally not recommended for use during pregnancy or while breastfeeding, as it may cause harm to the developing fetus or nursing child. It is important to consult your doctor for safer alternatives if you are pregnant, planning a pregnancy, or breastfeeding.

Can Voglistar GM 1/0.3 Tablet be taken with other medications?

This medicine can interact with several other medications. Inform your doctor about all medicines you are taking, including over-the-counter drugs, herbal supplements, and other antidiabetic medications or insulin. Specific interactions can occur with antibacterials, antifungals, certain anticancer drugs, beta-blockers, ACE inhibitors, NSAIDs, corticosteroids, diuretics, and some blood thinners.

What precautions should be taken while using Voglistar GM 1/0.3 Tablet?

• Alcohol: Avoid alcohol consumption, as it can increase the risk of hypoglycemia and a rare but serious condition called lactic acidosis.
• Medical Conditions: Do not take this medicine if you have Type 1 diabetes, severe kidney or liver disease, diabetic ketoacidosis, acute conditions (like severe infection or dehydration), severe ketosis, severe trauma, or certain lung or heart problems.
• Monitoring: Regularly monitor your blood sugar levels as advised by your doctor.
• Meals: Do not skip meals, especially when taking this medication, to avoid low blood sugar.
• Elderly Patients: Use with caution in elderly patients, as they may be more susceptible to side effects.
• Surgeries/Tests: Inform your doctor if you have an upcoming surgery or diagnostic tests involving contrast media, as the medication may need to be stopped temporarily.

What happens if a dose of Voglistar GM 1/0.3 Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should Voglistar GM 1/0.3 Tablet be stored?

Store Voglistar GM 1/0.3 Tablet in a cool and dry place, typically below 30°C, away from direct sunlight and moisture. Keep the medication out of reach of children.