Flucos 150 Tab

FLUCOS 150 TAB

Name:

• Common Name: Fluconazole
• Brand Name: FLUCOS 150 TAB (by OAKNET HEALTH (PHARMA))

Composition: Each tablet contains Fluconazole 150 mg as the active ingredient.

Uses: FLUCOS 150 TAB is an antifungal medication primarily used to treat a variety of fungal and yeast infections. It is effective against infections caused by Candida species. Specific conditions it is prescribed for include:

• Vaginal candidiasis (vaginal thrush) and associated candidal balanitis (penile thrush)
• Mucosal candidiasis, such as oral thrush (oropharyngeal candidiasis), esophageal candidiasis, and chronic mucocutaneous candidiasis
• Systemic candidiasis (invasive candidiasis) affecting the blood, brain, heart, eyes, or other parts of the body
• Cryptococcal meningitis (a fungal infection mainly affecting the lungs and brain)
• Fungal infections of the skin (dermatomycosis) including tinea pedis (athlete's foot), tinea corporis (ringworm), tinea cruris (jock itch), tinea versicolor, and dermal candida infections
• Nail infections (tinea unguinium/onychomycosis)
• Urinary tract infections (UTI) caused by Candida It can also be used for prophylaxis to prevent candidal infections in immunocompromised patients, such as those undergoing bone marrow transplants or individuals with HIV who are at high risk of recurrence.

Dosage and Administration: The dosage and duration of treatment for FLUCOS 150 TAB depend on the type and severity of the fungal infection. It should be taken exactly as prescribed by a doctor.

• Typical Guidance: Swallow the tablet whole with a glass of water. It can be taken with or without food.
• For vaginal candidiasis, a single 150 mg dose is often prescribed.
• For other infections, daily doses may range from 50 mg to 400 mg, and treatment should continue for the full prescribed duration, even if symptoms improve, to ensure complete eradication of the infection and prevent recurrence. Do not double doses if one is missed.

Side Effects: Common side effects of FLUCOS 150 TAB may include:

• Headache
• Nausea and Vomiting
• Diarrhea
• Abdominal pain
• Dizziness
• Skin rash

Serious side effects, though rare, require immediate medical attention:

• Severe allergic reactions (anaphylaxis), indicated by rash, itching, hives, swelling of the face, lips, tongue, or throat, and difficulty breathing.
• Heart rhythm changes (fast or irregular heartbeat, dizziness, fainting).
• Liver injury, characterized by right upper belly pain, loss of appetite, dark urine, yellowing of skin or eyes.
• Serious skin reactions, including widespread rash, high body temperature, and enlarged lymph nodes (DRESS syndrome).
• Adrenal gland problems, with symptoms like unusual tiredness, weakness, nausea, vomiting, or loss of appetite.

Precautions:

• Allergies: Do not take FLUCOS 150 TAB if you are allergic to fluconazole, other antifungal medicines, or any of its ingredients.
• Medical Conditions: Inform your doctor if you have liver or kidney problems, heart conditions (especially irregular heart rhythm or QT prolongation), or abnormal levels of potassium, calcium, or magnesium in your blood.
• Pregnancy and Breastfeeding: FLUCOS 150 TAB is generally not recommended during pregnancy as it may increase the risk of miscarriage; use effective contraception during treatment and for at least one week after the last dose. Breastfeeding may be maintained after a single dose of 150 mg, but is not recommended after repeated or high doses.
• Drug Interactions: FLUCOS 150 TAB can interact with numerous medications, potentially leading to serious side effects. Avoid concomitant use with certain antihistamines (terfenadine, astemizole), cisapride, pimozide, quinidine, and erythromycin. Consult your doctor about all medicines, supplements, and herbal products you are taking, especially blood thinners (e.g., warfarin), oral contraceptives, certain diabetes medications, NSAIDs, statins, and certain medications for depression or seizures.
• Alcohol: Avoid alcohol consumption during treatment, as it may worsen side effects and potential liver damage.
• Driving and Machinery: This medicine may cause dizziness or fits; caution is advised when driving or operating machinery.

Storage: Store FLUCOS 150 TAB below 30°C. Keep this medicine out of the reach of children.

FLUCOS 150 TAB, containing Fluconazole 150 mg, is an antifungal medication manufactured by OAKNET HEALTH (PHARMA). It is widely used to treat various fungal and yeast infections throughout the body.

What is FLUCOS 150 TAB used for?

FLUCOS 150 TAB is primarily used to treat a wide range of fungal infections. These include vaginal yeast infections, oral thrush (infections of the mouth and throat), fungal infections of the skin (such as ringworm and jock itch), nail infections, and infections of the urinary tract. It is also prescribed for more serious conditions like cryptococcal meningitis and systemic candidiasis (fungal infections affecting the blood, brain, heart, eyes, or other organs). Additionally, it can be used to prevent fungal infections in individuals with weakened immune systems, such as those with HIV, or undergoing chemotherapy, radiotherapy, or bone marrow transplants.

How does FLUCOS 150 TAB work?

FLUCOS 150 TAB contains fluconazole, which is an antifungal agent belonging to the triazole class. It works by inhibiting a fungal enzyme called ergosterol, which is a vital component of the fungal cell membrane. By disrupting the formation of the cell membrane, FLUCOS 150 TAB increases its permeability, preventing the fungi from growing and multiplying, ultimately leading to their death and clearing the infection.

What is the usual dosage for FLUCOS 150 TAB?

The dosage of FLUCOS 150 TAB varies depending on the type and severity of the infection. For vaginal candidiasis (vaginal yeast infection), the typical adult dosage is a single 150 mg oral tablet. For other infections, a doctor may prescribe daily doses ranging from 50 mg to 400 mg, or 150 mg thrice weekly, with treatment duration extending for several weeks to months. The tablet can be taken with or without food, preferably at a fixed time each day for optimal effectiveness.

What are the possible side effects of FLUCOS 150 TAB?

Common side effects may include headache, nausea, vomiting, diarrhea, abdominal pain, dizziness, upset stomach, and changes in the way food tastes. These are usually mild to moderate and temporary.

More serious side effects, though rare, require immediate medical attention. These include severe allergic reactions (such as skin rash, hives, itching, swelling of the face, lips, tongue, or throat, and difficulty breathing), liver problems (indicated by dark urine, yellowing of the skin or eyes, pale stools, unusual fatigue, loss of appetite, or stomach pain), severe skin reactions (like blistering or peeling skin with fever), changes in heart rhythm (fast or irregular heartbeat, dizziness, or fainting), adrenal gland problems, and seizures.

Is FLUCOS 150 TAB safe during pregnancy or breastfeeding?

Pregnancy: FLUCOS 150 TAB is generally not recommended during pregnancy, especially in the first trimester, as studies suggest a potential risk of miscarriage and specific birth defects, particularly with higher or prolonged doses. While a single 150 mg dose for vaginal candidiasis is considered to have a low risk of birth defects, it is still advised to consult a doctor. It is recommended to use reliable contraception during treatment and for at least one week after the last dose if you are of childbearing age.

Breastfeeding: Fluconazole passes into breast milk. A single dose of FLUCOS 150 TAB is generally considered compatible with breastfeeding. However, if repeated doses or high doses are prescribed, breastfeeding is generally not recommended, and infants should be monitored for gastrointestinal symptoms. Always consult your doctor before using this medication if you are breastfeeding.

Can FLUCOS 150 TAB be taken with other medications?

FLUCOS 150 TAB can interact with several other medications. It is crucial to inform your doctor about all prescription, over-the-counter, and herbal medicines you are taking. Significant interactions can occur with medications such as:

• Hypoglycemic agents (e.g., glipizide, glyburide) which may increase the risk of low blood sugar.
• Anticoagulants (e.g., warfarin) which can enhance their blood-thinning effects.
• Benzodiazepines (e.g., midazolam, triazolam) leading to increased effects of these medicines.
• Calcium channel blockers (e.g., amlodipine, nifedipine).
• Immunosuppressants (e.g., cyclosporine, tacrolimus, sirolimus).
• Certain antihistamines (e.g., astemizole, terfenadine).
• Oral contraceptive pills may have reduced effectiveness; barrier methods of contraception are advised.
• Medicines that can affect heart rhythm (e.g., amiodarone, pimozide, quinidine). Additionally, it's advised to avoid antacid treatments within one hour before or two hours after taking FLUCOS 150 TAB.

What precautions should be taken with FLUCOS 150 TAB?

Before taking FLUCOS 150 TAB, inform your doctor if you have a history of liver disease, kidney disease, heart problems (especially irregular heart rhythm), abnormal electrolyte levels (potassium, calcium, or magnesium), severe skin reactions, or adrenal insufficiency. Avoid alcohol consumption as it may worsen side effects like dizziness. If you experience dizziness or fits, do not drive or operate machinery. Do not stop the medication suddenly, even if symptoms improve, as the infection may return or become resistant. For prolonged treatment (over a month), your doctor may recommend regular monitoring of your liver function.

What happens if a dose of FLUCOS 150 TAB is missed?

If you miss a dose of FLUCOS 150 TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects.

How should FLUCOS 150 TAB be stored?

FLUCOS 150 TAB should be stored at room temperature, typically below 30°C (86°F). Keep the tablets in their original packaging, in an airtight container, and protect them from heat and moisture. Do not store the medicine in damp places such as bathrooms. Always keep FLUCOS 150 TAB out of the reach of children.