Thyrox 112 Mcg Tablet (100 Tab)

THYROX 112 MCG TABLET (100 TAB) by MACLEODS PHARMACEUTICALS LTD.

Thyrox 112 MCG Tablet is a medication used in thyroid hormone replacement therapy, manufactured by Macleods Pharmaceuticals Ltd.

• Name:

  • Brand Name: Thyrox 112 Tablet
  • Common Name: Levothyroxine Sodium

• Composition:

  • Each tablet contains Thyroxine (as Thyroxine Sodium) 112 mcg.

• Uses: Thyrox 112 Tablet is primarily prescribed for the management of:

  • Hypothyroidism: A condition where the thyroid gland does not produce sufficient thyroid hormones. It replaces the deficient hormones to restore normal thyroid function, improving metabolism, energy levels, mood, and other bodily functions.
  • Euthyroid Goitre: To suppress pituitary TSH secretion, which can help prevent or manage an abnormal enlargement of the thyroid gland.
  • Thyrotropin-dependent, well-differentiated thyroid cancer: As an adjunctive therapy.

• Dosage and Administration:

  • Thyrox 112 Tablet is typically taken orally once daily, on an empty stomach, preferably 30 minutes to 1 hour before breakfast, with a full glass of water.
  • The tablet should be swallowed whole and not crushed or chewed.
  • Dosage is individualized by a doctor based on the patient's age, weight, medical condition, lab test results, and response to treatment.
  • It is crucial not to stop taking the medicine without consulting a doctor, as thyroid replacement therapy is often a lifelong requirement.
  • Allow a gap of at least 4 hours between taking Thyrox 112 Tablet and certain medications or supplements like antacids, calcium, or iron supplements, as these can interfere with its absorption.

• Side Effects: Common side effects, especially if the dose is higher than needed, may include:

  • Nervousness, irritability, restlessness, mood swings.
  • Tremors (shaking or trembling).
  • Palpitations, fast or irregular heartbeat.
  • Headache.
  • Insomnia (difficulty sleeping).
  • Diarrhea, vomiting.
  • Weight loss, increased appetite.
  • Sweating, sensitivity to heat, fever.
  • Hair loss (especially in children, usually reversible).
  • Muscle cramps, muscle weakness.
  • Changes in the menstrual cycle.

  Serious side effects requiring immediate medical attention include very high temperature, confusion, low blood pressure, yellowness in the eye/skin, or fits.

• Precautions:

  • Untreated Conditions: Avoid use in patients with untreated adrenal insufficiency or hyperthyroidism.
  • Cardiovascular Disorders: Caution is advised for patients with cardiovascular conditions such as angina, coronary artery disease, or hypertension, as thyroid hormones can increase the heart's workload. Close monitoring is necessary.
  • Diabetes Mellitus: Thyrox 112 Tablet may affect blood sugar levels, requiring dose adjustments of antidiabetic medications. Regular blood sugar monitoring is recommended.
  • Osteoporosis: Long-term use, particularly in post-menopausal women, may impact bone mineral density. Doctors may prescribe calcium or vitamin D supplements.
  • Pregnancy and Breastfeeding: Pregnant women may require dose adjustments under medical supervision. It is generally considered safe for lactating women if prescribed by a doctor.
  • Drug Interactions: Inform your doctor about all medications, including over-the-counter drugs and herbal products, as Thyrox 112 Tablet can interact with antidepressants, antidiabetic agents, calcium carbonate, iron supplements, antacids, anti-ulcer medicines, cholesterol-reducing agents (e.g., cholestyramine), antipsychotic medicines, anti-epileptic medicines (e.g., Phenytoin), and oral contraceptives.
  • Not for Weight Loss: This medication should not be used for weight loss, as normal doses are ineffective, and large doses can cause serious, potentially fatal side effects.

• Storage:

  • Store in a cool and dry place, below 25°C or 30°C.
  • Keep away from direct sunlight, heat, and humidity.
  • Store in the original container and keep out of sight and reach of children.

Here are frequently asked questions about THYROX 112 MCG TABLET:

What is THYROX 112 MCG TABLET used for?

THYROX 112 MCG TABLET is primarily used to treat an underactive thyroid gland, a condition known as hypothyroidism. It works by replacing the thyroid hormone (thyroxine) that your body isn't producing enough of. This helps to regulate the body's energy, metabolism, mood, and other vital functions that are affected by low thyroid hormone levels. It can also be used to manage euthyroid goitre and as an adjunctive therapy for certain types of thyroid cancer.

How does THYROX 112 MCG TABLET work?

THYROX 112 MCG TABLET contains Levothyroxine sodium, which is a synthetic version of thyroxine (T4), a hormone naturally produced by your thyroid gland. Once in the body, it is converted into triiodothyronine (T3), the active form of the hormone. This hormone then works to restore normal thyroid function by regulating various physiological processes such as metabolism, growth, body temperature, and heart rate.

What is the usual dosage of THYROX 112 MCG TABLET?

The dosage of THYROX 112 MCG TABLET is highly individualized and determined by your doctor based on your medical condition, age, weight, and regular thyroid function test results. It is typically taken once daily on an empty stomach, ideally 30 to 60 minutes before breakfast, with a full glass of water. For most people, this medication is a lifelong treatment.

What are the possible side effects of THYROX 112 MCG TABLET?

Side effects are usually experienced when the dose is too high. Common side effects may include headache, vomiting, sweating, weight loss, tremors, restlessness, excitability, nervousness, irritability, difficulty sleeping (insomnia), increased appetite, diarrhea, muscle cramps, muscle weakness, and palpitations (irregular or fast heartbeat). In children, temporary hair loss can occur. If you experience very high temperature, a very fast or irregular heart rate, low blood pressure, confusion, or yellowness of the eyes/skin, seek immediate medical attention. It is important to note that this medication should not be used for weight loss.

Is THYROX 112 MCG TABLET safe during pregnancy or breastfeeding?

Pregnancy: THYROX 112 MCG TABLET is generally considered safe for use during pregnancy if prescribed by your doctor. It is crucial to inform your doctor if you are pregnant or planning to conceive, as your dose may need to be adjusted to ensure proper fetal development. Breastfeeding: This medication is also generally safe to use while breastfeeding. Levothyroxine passes into breast milk in very small amounts that are unlikely to harm the nursing infant. Adequate thyroid hormone levels are essential for normal milk production.

Can THYROX 112 MCG TABLET be taken with other medications?

Yes, but several medications and supplements can interact with THYROX 112 MCG TABLET, affecting its absorption or effectiveness. These include antacids, calcium or iron supplements, multivitamins, proton pump inhibitors, sucralfate, cholesterol-lowering drugs, and certain antibiotics (e.g., ciprofloxacin). Other medications like antidiabetic drugs, blood thinners, oral contraceptives, and some anti-epileptic medicines may require a dose adjustment of Thyrox. Always inform your doctor about all medicines, supplements, and herbal products you are taking. It is recommended to maintain a gap of at least 4 hours between taking Thyrox and antacids, calcium or iron supplements, and multivitamins.

What precautions should be taken while on THYROX 112 MCG TABLET?

Do not stop taking THYROX 112 MCG TABLET without consulting your doctor. Inform your doctor if you have existing heart conditions (such as high blood pressure, angina, or irregular heart rhythm), diabetes mellitus, or osteoporosis, as the medication may require careful monitoring and dose adjustments. It should not be used if you have untreated adrenal insufficiency or hyperthyroidism. Regular monitoring of your thyroid hormone levels is essential to ensure the medication is working effectively and to adjust the dose as needed.

What happens if a dose of THYROX 112 MCG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one unless specifically instructed by your doctor. Due to the long half-life of levothyroxine, missing a single dose usually does not cause significant problems. Contact your doctor if you miss two or more doses consecutively.

How should THYROX 112 MCG TABLET be stored?

THYROX 112 MCG TABLET should be stored below 25°C in a cool and dry place, away from direct sunlight and moisture. Keep the tablets in their original container and ensure they are out of the sight and reach of children and pets.