Lacotide 200 Mg Tablet (10 Tab)

LACOTIDE 200 MG TABLET

LACOTIDE 200 MG TABLET, manufactured by INTAS PHARMACEUTICALS LTD., is an antiepileptic medication used to manage seizures.

• Name:

  • Brand Name: LACOTIDE 200 MG TABLET
  • Common Name: Lacosamide

• Composition:

  • Each tablet contains 200 mg of Lacosamide as the active ingredient.

• Uses: LACOTIDE 200 MG TABLET is primarily used for the treatment and prevention of partial-onset seizures in patients with epilepsy. It can be prescribed as a monotherapy or as an add-on (adjunctive) therapy when other medications are not sufficient to control seizures in adults and adolescents (typically 4 years and older, though some sources mention 1 month and older for partial-onset seizures).

• Dosage and Administration: LACOTIDE 200 MG TABLET should be taken orally with a glass of water, with or without food, preferably at the same time each day to maintain consistent levels in the body. The tablet should be swallowed whole and not broken, cut, or chewed. The exact dose and frequency are determined by a medical professional based on individual factors like age, weight, condition severity, and response to treatment. For adults, an initial recommended dosage is typically 50 mg twice daily, which can be gradually increased to a maximum of 400 mg per day as directed by the doctor. Do not exceed the prescribed dose or stop the medicine suddenly without consulting a doctor, as this may increase seizure frequency.

• Side Effects:

  • Common Side Effects: Dizziness, headache, nausea, vomiting, double vision (diplopia), fatigue, blurred vision, sleepiness, dry mouth, and muscle spasms. Most of these are usually mild and temporary.
  • Serious Side Effects: Symptoms of abnormal heartbeat (such as rapid, irregular, or slow heartbeat, palpitations, shortness of breath, feeling lightheaded, fainting), suicidal thoughts or behaviors, and changes in mood or cognitive function. Report any persistent or unusual symptoms to your doctor immediately.

• Precautions:

  • Inform your doctor about any pre-existing health conditions, especially heart rhythm issues, liver or kidney problems, or a history of substance use disorder.
  • Caution is advised during pregnancy and breastfeeding; LACOTIDE 200 MG TABLET is generally not recommended unless clearly necessary and advised by a healthcare provider.
  • Avoid consuming alcohol as it may increase the risk of side effects like dizziness and drowsiness.
  • This medicine may cause dizziness, drowsiness, or blurred vision, so avoid driving or operating heavy machinery until you know how it affects you.
  • Do not abruptly discontinue the medication without medical supervision.

• Storage: Store LACOTIDE 200 MG TABLET in a cool and dry place, ideally at room temperature below 30°C. Protect it from direct sunlight and moisture, and ensure it is out of reach and sight of children. Always check the expiry date before use.

LACOTIDE 200 MG TABLET contains Lacosamide, an anticonvulsant medication. It is used to manage and prevent seizures in individuals with epilepsy.

What is LACOTIDE 200 MG TABLET used for?

LACOTIDE 200 MG TABLET is primarily used to treat partial-onset seizures in adults and children aged 4 years and older. It can be used alone (monotherapy) or as an add-on therapy with other antiepileptic drugs, especially when other medications are not sufficient to control seizures. It is also used as adjunctive therapy for primary generalized tonic-clonic seizures in patients 4 years and older.

How does LACOTIDE 200 MG TABLET work?

LACOTIDE 200 MG TABLET works by selectively enhancing the slow inactivation of voltage-gated sodium channels in the brain. This action stabilizes hyperexcitable neuronal membranes and reduces abnormal electrical activity, thereby helping to control and prevent seizures. Unlike some other antiepileptic drugs, it does not affect the fast inactivation of voltage-gated sodium channels.

What is the usual dosage of LACOTIDE 200 MG TABLET?

The exact dose and frequency are determined by a medical professional based on individual patient response, age, and body weight. For adults, a typical starting dose for adjunctive therapy for partial-onset seizures or primary generalized tonic-clonic seizures is 50 mg twice daily. For monotherapy, an initial dosage of 100 mg twice daily is common. The maximum recommended dosage for both monotherapy and adjunctive therapy is generally 200 mg twice daily (400 mg per day). It is usually taken orally with water, with or without food, at the same time each day for consistency. Tablets should be swallowed whole and not crushed or chewed.

What are the possible side effects of LACOTIDE 200 MG TABLET?

Common side effects may include dizziness, headache, nausea, vomiting, fatigue, blurred vision, double vision (diplopia), dry mouth, and coordination difficulties. Most of these are mild and temporary. More serious but rare side effects can include changes in heart function (e.g., slow or irregular heartbeat), mood changes (depression, suicidal thoughts), and allergic reactions. It may also cause weight gain in some individuals.

Is it safe during pregnancy or breastfeeding?

LACOTIDE 200 MG TABLET is generally not recommended for use in pregnant women unless considered clearly necessary and advised by a doctor after assessing the benefits and risks. For breastfeeding women, LACOTIDE 200 MG TABLET is generally not recommended as it may pass into breast milk. Limited information suggests low levels in milk with a 200 mg daily maternal dose, but careful monitoring for drowsiness and adequate weight gain in the infant is advised if used during breastfeeding.

Can it be taken with other medications?

LACOTIDE 200 MG TABLET may interact with certain other medications. It's important to inform your doctor about all medications you are taking, including prescription, over-the-counter, herbal products, and supplements.

• Other antiepileptic drugs (AEDs): Drugs like carbamazepine or phenytoin may affect LACOTIDE's effectiveness, and LACOTIDE may slightly increase their levels.
• Medicines affecting heart rhythm: Taking LACOTIDE with drugs like metoprolol, amiodarone, or digoxin may increase the risk of irregular heart rhythms.
• CNS depressants: Combining with sedatives, anti-anxiety medicines, or sleep aids (e.g., diazepam, clonazepam) can increase drowsiness, dizziness, or trouble concentrating.
• CYP2C9 inducers and inhibitors: As lacosamide is metabolized by CYP2C9, medications that induce or inhibit this enzyme could alter its metabolism and effectiveness.
• Alcohol: Alcohol can enhance sedative and dizziness-related side effects and should be avoided or limited.

What precautions should be taken?

• Heart conditions: Inform your doctor about any existing heart rhythm issues, heart failure, or a history of heart attack, as LACOTIDE can affect heart conduction.
• Liver and kidney problems: Use with caution in patients with liver or kidney disease; dosage adjustments may be necessary. Severe liver disease may contraindicate its use.
• Dizziness and drowsiness: LACOTIDE can cause dizziness, drowsiness, or blurred vision. Avoid driving or operating heavy machinery until you know how it affects you.
• Sudden discontinuation: Do not stop taking LACOTIDE suddenly without consulting your doctor, as this can increase the risk of seizures.
• Mental health: Be aware of potential mood changes, including suicidal thoughts or behaviors, and report these to your doctor immediately.
• Allergies: Do not take LACOTIDE if you are allergic to lacosamide or any of its ingredients.

What happens if a dose is missed?

If you miss a dose of LACOTIDE 200 MG TABLET, take it as soon as you remember. However, if it is close to the time for your next scheduled dose (e.g., more than 6 hours past the scheduled time), it is best to skip the missed one and continue with your regular dosing routine. Do not take a double dose to make up for the missed tablet, as this could lead to unwanted side effects. Missing doses can reduce the consistency of nerve signal support and potentially trigger seizures, so it's advisable to take the tablet at the same time every day.

How should it be stored?

LACOTIDE 200 MG TABLET should be stored in a cool and dry place, ideally at room temperature (below 30°C or between 20°C to 25°C). Keep it away from direct sunlight, moisture, and out of reach and sight of children. Always check the expiry date on the packet before use.