Trifluxy P-5mg Tab

TRIFLUXY P-5MG TAB: Detailed Product Description

TRIFLUXY P-5MG TAB, manufactured by Tripada Healthcare, is a medication primarily used in the management of certain psychiatric and neurological conditions.

Name

• Common Names: Trifluoperazine and Trihexyphenidyl
• Brand Name: TRIFLUXY P-5MG TAB

Composition

Each tablet of TRIFLUXY P-5MG contains:

• Trifluoperazine: 5 mg
• Trihexyphenidyl: 2 mg

Uses

TRIFLUXY P-5MG TAB is prescribed for the treatment of:

• Schizophrenia: This medicine helps manage symptoms such as hallucinations, delusions, disorganized thinking, and emotional disturbance by inhibiting dopamine receptors in the brain.
• Anxiety: It may be used for short-term treatment of anxiety, particularly when other anxiety medications have not been effective.
• Depression: It can be used for short periods to relieve symptoms of depression.
• Nausea and Vomiting: The trifluoperazine component blocks dopamine receptors in the chemoreceptor trigger zone (CTZ), helping to control nausea and vomiting.
• Parkinson's Disease and Drug-induced Extrapyramidal Symptoms (EPS): Trihexyphenidyl helps to increase muscle control and decrease muscle stiffness, addressing symptoms of Parkinson's disease and extrapyramidal symptoms that can be caused by other antipsychotic medications, including trifluoperazine.

Dosage and Administration

The dosage should be as directed by a healthcare professional. For schizophrenia, the recommended dosage for Trifluxy P 5mg Tablet is typically one tablet daily. It can be taken with or without food, and it is best taken at the same time each day to maintain a consistent level of medicine in the body. Due to potential drowsiness, taking it at night may be advised.

Side Effects

Common Side Effects:

• Drowsiness, dizziness, or feeling unsteady
• Dry mouth, constipation, nausea, vomiting, loss of appetite
• Blurred vision
• Restlessness, weakness, fatigue, sleeplessness
• Headache, abdominal pain
• Difficulty urinating
• Skin reactions/rash, increased sweating
• Weight gain
• Orthostatic hypotension (sudden drop in blood pressure upon standing)
• Increased prolactin levels (may cause breast enlargement or milk production)

Serious Side Effects (Seek immediate medical attention if experienced):

• Neuroleptic Malignant Syndrome (NMS): Symptoms include high fever, stiff muscles, confusion, sweating, and changes in heart rate and blood pressure.
• Tardive Dyskinesia: Uncontrollable and repetitive body movements, especially of the face, tongue, or other body parts. This risk increases with long-term use and can be permanent.
• Extrapyramidal Symptoms (EPS): Muscle stiffness, spasms, tremors, loss of balance or coordination, restlessness, shuffling walk.
• Liver injury (yellowing of skin or eyes, right upper belly pain, unusual weakness)
• Severe low blood pressure
• Seizures
• Sudden eye pain or changes in vision, such as blurry vision or seeing halos around lights
• Allergic reactions (skin rash, hives, swelling of the face, lips, tongue, or throat)

Precautions

• Elderly Patients with Dementia: There is an FDA black box warning for an increased risk of death in elderly patients with dementia-related psychosis treated with antipsychotic drugs like trifluoperazine.
• Discontinuation: Do not stop taking this medication suddenly without consulting a healthcare professional, as it can worsen symptoms or lead to severe withdrawal reactions.
• Alcohol: Avoid consuming alcohol during treatment, as it can increase drowsiness and other side effects.
• Alertness: This medication may cause drowsiness, dizziness, and affect thinking and movements. Do not drive or operate machinery until you know how it affects you.
• Sun Sensitivity: This medication can make you more sensitive to the sun. Wear protective clothing and use sunscreen when outdoors.
• Body Temperature Regulation: It may make it harder for your body to regulate temperature. Use caution in extreme heat or cold.
• Pre-existing Conditions: Inform your doctor if you have heart disease, liver disease, kidney disease, glaucoma, seizure disorders, low blood counts, Parkinson's disease, prostate disease, diabetes, or a history of neuroleptic malignant syndrome.
• Pregnancy and Breastfeeding: The safety of this medication during pregnancy and breastfeeding has not been definitively established, and it may pose risks to the newborn. Discuss potential risks and benefits with your doctor.
• Diabetes: Monitor blood glucose levels regularly if you have diabetes, as this medicine may affect sugar levels.
• Drug Interactions: Inform your healthcare provider about all other medications, herbs, non-prescription drugs, or dietary supplements you are taking, as interactions can occur.

Storage

Store TRIFLUXY P-5MG TAB below 30°C. Keep the container tightly closed and out of the reach of children.

TRIFLUXY P-5MG TAB is a medicine manufactured by TRIPADA HEALTHCARE. It is a combination medication containing Trifluoperazine 5mg and Trihexyphenidyl 2mg.

Here are some frequently asked questions about TRIFLUXY P-5MG TAB:

What is TRIFLUXY P-5MG TAB used for?

TRIFLUXY P-5MG TAB is primarily used to prevent and treat relapses of schizophrenia, a mental illness that affects a person's ability to think, feel, and behave clearly. It may also be used for short-term relief of anxiety and depression, to manage nausea and vomiting, and to treat Parkinson's disease and drug-induced extrapyramidal symptoms.

How does TRIFLUXY P-5MG TAB work?

This medicine contains two active ingredients. Trifluoperazine, an antipsychotic, works by inhibiting dopamine receptors in the brain, which are involved in regulating mood, behavior, and emotions. Trihexyphenidyl is included to help manage potential side effects of Trifluoperazine, such as involuntary movements like hand shaking and muscle spasms.

What is the usual dosage of TRIFLUXY P-5MG TAB?

The dosage should be taken as prescribed by your doctor. For adults, the usual dose for schizophrenia can range from 2-5 mg orally twice a day, while for anxiety, it might be 1-2 mg orally twice a day. For children aged 6-12 years, up to 4 mg daily in divided doses may be prescribed. It can be taken with or without food, but it is best to take it at the same time every day to maintain a consistent level of medication in the body.

What are the possible side effects of TRIFLUXY P-5MG TAB?

Common side effects may include restlessness, weakness, drowsiness, dizziness, dry mouth, loss of appetite, blurred vision, muscle weakness, fainting on standing up, confusion, weight gain, water retention, nausea, constipation, sedation, orthostatic hypotension (sudden drop in blood pressure upon standing), urinary retention, increased prolactin levels, and nervousness. If side effects persist or worsen, consult your doctor. More serious side effects, though rare, can include Neuroleptic Malignant Syndrome and Tardive Dyskinesia.

Is TRIFLUXY P-5MG TAB safe during pregnancy or breastfeeding?

TRIFLUXY P-5MG TAB is generally not recommended during pregnancy, particularly in the third trimester, as it may cause adverse effects in the baby. It is also generally not recommended during breastfeeding. Always consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding before taking this medication.

Can TRIFLUXY P-5MG TAB be taken with other medications?

It's important to inform your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements, to avoid potential interactions. Critical interactions have been noted with medications such as Metoclopramide, Ziprasidone, Potassium citrate, and Potassium chloride. Additionally, consuming alcohol with TRIFLUXY P-5MG TAB is not recommended as it can increase drowsiness and dizziness.

What precautions should be taken while using TRIFLUXY P-5MG TAB?

Avoid driving or operating machinery if you experience drowsiness, dizziness, or blurred vision. Use with caution in elderly patients due to an increased risk of adverse reactions. The tablet form is not recommended for children below 6 years of age. Inform your doctor if you have pre-existing conditions such as liver, kidney, or heart problems, glaucoma, prostate problems, urination difficulties, stomach ulcers, myasthenia gravis, tardive dyskinesia, alcoholism, high blood pressure, diabetes, blood disorders, or a history of seizures. Do not stop taking this medicine abruptly without consulting your doctor, as it can worsen symptoms. This medicine may also make you sweat less, increasing the risk of heatstroke, so drink plenty of fluids and dress lightly in hot weather.

What happens if a dose of TRIFLUXY P-5MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double or extra dose to make up for a missed one.

How should TRIFLUXY P-5MG TAB be stored?

TRIFLUXY P-5MG TAB should be stored in a cool, dry place, away from direct sunlight, and out of the sight and reach of children. It should be kept at temperatures between 10ºC to 25ºC or below 30ºC.